Annual Cannabinoid Research Society Symposium on the Cannabinoids

项目总结 大麻素信号通路由大麻素受体CB1和CB2及其同源外源受体组成 和内源性配体。大麻素信号广泛分布于中枢和外周 它与多种重要的神经生物学过程有关，包括能量调节 动态平衡、学习和记忆、运动功能、奖励、焦虑和社会功能。此外，使用 大麻在过去十年中有所增加，预计将继续增加，面对 在美国扩大反禁酒令运动。易受伤害人群和 在关键时期，如青春期和妊娠期，风险不明确，是紧张的焦点 正在进行的科学调查。与这些日益增长的潜在公共卫生问题相称， 大麻素及其与脑相关的内源性大麻素的基础生物学研究 发展、功能和病理越来越受到公众、政策制定者、 研究人员和医疗保健专业人员。因此，了解大麻素的神经生物学 信号可能对生理功能和体细胞和细胞的病理生理学有广泛的影响 神经精神障碍。国际大麻素研究会(ICRS)是唯一的年度 致力于传播有关大麻类科学各方面的科学信息的科学会议。 ICRS将于2021年举行第31届年度研讨会，在这一领域取得了前所未有的成功 大麻素研究。在上一个供资周期中，国家卫生研究院的支持使ICRS能够提供 提供大量差旅支持，以增加学员出席我们年度会议的人数。学生车船津贴 将利用该方案增加早期大麻研究人员对ICRS的参与 关于大麻素的研讨会。一直并将继续特别强调支持 在科学界传统上代表性不足的个人，包括女性和美国种族和民族 少数族裔。除了旅游奖励计划外，我们还建议提供一个职业发展计划 在每次ICRS年度研讨会上，表彰优秀的博士后和博士后 在每次研讨会期间发表演讲并颁发奖项，并出版一本印刷形式的摘要书， 将在年度专题讨论会结束后在ICRS网站上向公众公布。完成这些工作 AIMS将继续通过促进出席和 在开放、包容和平等的论坛上展示他们的原创研究，并提供网络 并在大麻类药物研究的所有领域为年轻科学家提供指导机会。

PROJECT SUMMARY Cannabinoid signaling is composed of Cannabinoid receptors CB1 and CB2 and their cognate exogenous and endogenous ligands. Cannabinoid signaling is widely distributed throughout the CNS and periphery and is implicated in a wide variety of important neurobiological processes including regulation of energy homeostasis, learning and memory, motor function, reward, anxiety, and social function. Moreover, use of cannabis has increases over the past decade and is expected to continue to increase in the face of the expanding anti-prohibition movement in the United States. Cannabis use by vulnerable populations and during critical periods, such as adolescence and pregnancy, carry unclear risk and are the focus of intense ongoing scientific investigation. Commensurate with these growing potential public health concerns, research into the fundamental biology of cannabinoids and endogenous cannabinoids related to brain development, function, and pathology are becoming of greater interest to the public, policymakers, researchers and healthcare professionals. Therefore, understanding the neurobiology of cannabinoid signaling could have broad implications for physiological function and the pathophysiology of somatic and neuropsychiatric disorders. The International Cannabinoid Research Society (ICRS) is the only annual scientific meeting devoted to dissemination of scientific information on all aspects of cannabinoid sciences. The ICRS will hold its 31st annual symposium in 2021 and has been an unparalleled success in the field of cannabinoid research. During the previous funding cycle, NIH support has allowed the ICRS to provide substantial travel support to increase trainee attendance at our annual meeting. The student travel grant program will be used to increase the participation of early stage cannabinoid researchers in the ICRS Symposia on the Cannabinoids. Special emphasis has been, and will continue to be, placed on support for individuals traditionally underrepresented in science, including women and U.S. racial and ethnic minorities. In addition to the travel award program, we propose to provide a career development program at each annual ICRS symposium, recognize outstanding predoctoral and postdoctoral student presentations with awards given during each symposium, and publish an abstract book in printed form that will be made available to the public on the ICRS website after the annual symposium. Completion of these aims will continue to invigorate the next generation of cannabinoid scientists by facilitating attendance and presentation of their original research in an open, inclusive, and egalitarian forum and provide networking and mentorship opportunities to young scientists in all areas of cannabinoid research.