Personalized Cystic Fibrosis Therapy and Research Center

项目总结：《试点和可行性方案》将促进新的和早期的发展 为创新和前沿项目提供种子支持，以快速推进 个性化囊性纤维化治疗研究中心的科研兴趣 (PCFC)。 该计划旨在支持与个性化配置文件相关的高度创新研究 并协助新的和早期阶段的调查人员过渡以获得外部资金 并维持他们的个人研究计划。我们有几个新的和早期的调查人员在 CCHMC热衷于个性化的慢性阻塞性肺疾病药物研究。他们目前没有NIH RO1 资助，但有其他类型的资助，如NIH K型奖和R03奖，来自私人的支持 基金会(即Parker B Francis、CFF、美国心脏协会(AHA)、辛辛那提儿童研究 基金会(CCRF，仅举几例)。此外，我们还将鼓励那些希望 将他们的研究计划扩展到个性化的CF药物研究。筹委会的目的是 鼓励这些研究人员开发一项创新的研究计划，在 与CF/CFTR相关的基础研究领域，并开发个性化的CF医学翻译程序 主题。

PROJECT SUMMARY: The “Pilot and Feasibility Program” will foster the development of new and early stage investigators and to provide seed-support for innovative and cutting edge projects to rapidly advance the scientific and research interests of the Personalized Cystic Fibrosis Therapy and Research Center (PCFC). This program is designed to support highly innovative research relevant to personalized CF medicine and to facilitate the transition of new and early stage investigators to obtain extramural funding and to sustain their individual research program. We have several new and early stage investigators at CCHMC who are passionate in personalized CF medicine research. They currently do not have NIH RO1 funding, but have other types of funding such as NIH K-type award and RO3 award, support from private foundations (i.e., Parker B Francis, CFF, American Heart Association (AHA), Cincinnati Children’s Research Foundation (CCRF), to name a few). In addition, we will also encourage established investigators who wish to extend their research program into personalized CF medicine research. It is the intention of the PCFC to encourage these investigators to develop an innovative research program that would blaze new trails in the area of CF/CFTR related basic research and develop translational program with personalized CF medicine theme.