Acute traumatic coagulopathy- mechanisms and measurement

急性创伤性凝血病（ATC）是指严重创伤后凝血功能受损，与早期高死亡率相关。无法预测这种疾病和知识贫乏，其详细的生化机制，阻碍了发展的证据为基础的指南，以管理ATC患者。该项目旨在将早期生化障碍与创伤后临床管理和结果相关联，以确定导致ATC的机制并确定管理策略。

Acute traumatic coagulopathy (ATC) refers to impaired blood clotting post major trauma and is associated with high, early mortality. Inability to predict this disorder and poor knowledge regarding its detailed biochemical mechanism has hindered development of evidence based guidelines to manage patients with ATC. This project aims to correlate early biochemical disorders with clinical management and outcomes post trauma to determine mechanisms leading to ATC and determine management strategies.