Acute traumatic coagulopathy- mechanisms and measurement

急性创伤性凝血病 - 机制和测量

• 批准号: nhmrc : 1072579
• 负责人: Prof Biswadev Mitra
• 金额: $ 12.55万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Early Career Fellowships
• 财政年份: 2014
• 资助国家: 澳大利亚
• 起止时间: 2014-01-01 至 2017-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/acute-traumatic-coagulopathy-mechanisms-measurement/455521
• 关键词: Acute; traumatic; coagulopathy; mechanisms; measurement

Acute traumatic coagulopathy (ATC) refers to impaired blood clotting post major trauma and is associated with high, early mortality. Inability to predict this disorder and poor knowledge regarding its detailed biochemical mechanism has hindered development of evidence based guidelines to manage patients with ATC. This project aims to correlate early biochemical disorders with clinical management and outcomes post trauma to determine mechanisms leading to ATC and determine management strategies.

急性创伤性凝血病 (ATC) 是指重大创伤后凝血功能受损，与高早期死亡率相关。无法预测这种疾病以及对其详细生化机制的了解不足，阻碍了 ATC 患者管理循证指南的制定。该项目旨在将早期生化疾病与临床管理和创伤后结果相关联，以确定导致 ATC 的机制并确定管理策略。