UAB CFRC Pilot and Feasibility Program

项目总结/摘要 UAB P30中心内的试点项目有助于我们校园的多学科研究，提高 教师发展，广泛利用科学核心，并与全球研究主题， UAB中心一个强有力和得到良好支持的试点和可行性机制使中心能够 解决新的研究重点，扩大其科学范围。P30试点项目的目标和可行性 通过四个具体目标来描述组成部分。首先，试点计划确定并支持新的 优秀的质量和创新的研究项目。每个项目通常持续一到两年， 与UAB P30的总体目标一致，旨在从以下方面获得进一步的赠款支持 NIH、囊性纤维化（CF）基金会或其他资助机构。二是试点方案支持 通过资助优秀的试点研究，在职业发展方面有前途的初级教师。中心 强化计划，CF中心内的强大指导，强大的强化计划，以及广泛的 通过临床和转化科学中心（UAB的NIH- 资助的CTSA研究计划）也被用于这一目的。第三，试点方案扩大了 CF研究的广度和质量，通过资助具有宝贵价值的知名研究人员的创新项目， 专家谁是新的CF研究，或者从建立CF调查谁想要测试新的 高影响力的假设第四，试点方案提供了一个审查和 监督试点和可行性研究。这包括广泛征求和严格的同行审查试点 申请，向内部咨询委员会提出关于试点项目第二年供资的建议， 协助和指导试点PI，并记录有关出版物和赠款结果， 从试点资金中提取资金，为持续的流程改进提供证据。总的来说，试点项目已经 对UAB的CF研究产生了重要影响，在早期帮助多个教师方面非常成功， 职业成功地获得CF研究的校外资金，并扩大了我们的研究基地， 新的创新方向。

PROJECT SUMMARY / ABSTRACT Pilot projects within the UAB P30 Center contribute to multidisciplinary research on our campus, enhance faculty development, extensively utilize Scientific Cores, and integrate well with the global research themes of the UAB Center. A strong and well-supported Pilot and Feasibility mechanism has allowed the Center to address new research priorities and expand its scientific purview. The goals of the P30 Pilot and Feasibility Component are delineated through four Specific Aims. First, the Pilot Program identifies and supports new research projects of outstanding quality and innovation. Projects typically last one to two years each, are concordant with the overall objectives of the UAB P30 and are intended to result in further grant support from NIH, Cystic Fibrosis (CF) Foundation, or other funding agencies. Second, the Pilot Program supports promising junior faculty in career development through funding of outstanding pilot research. The Center Enrichment Program, strong mentoring within the CF Center, a robust Enrichment program, and extensive training resources available at UAB through the Center for Clinical and Translational Science (UAB’s NIH- funded CTSA research program) are also employed toward this end. Third, the Pilot Program augments the breadth and quality of CF research by funding innovative projects from established researchers with valuable expertise who are new to CF research, or alternatively from established CF investigators who want to test new high-impact hypotheses. And fourth, the Pilot Program provides an administrative framework for review and oversight of Pilot and Feasibility Studies. This includes broad solicitation and rigorous peer review of Pilot applications, recommendations regarding 2nd-year funding of Pilots to the Internal Advisory Committee, assistance and mentoring to pilot PIs, and record-keeping regarding publication and grant outcomes that result from pilot funding to provide evidence for continuous process improvement. Overall, the Pilot Program has had an important impact on CF research at UAB, has been very successful in assisting multiple faculty early in their careers to successfully obtain extramural funding for CF research, and has enlarged our Research Base in new innovative directions.