Institutional Career Development Core

机构职业发展核心

• 批准号: 10674613
• 负责人: NILUFER ERTEKIN-TANER
• 金额: $ 104.44万
• 依托单位: MAYO CLINIC ROCHESTER
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-09-18 至 2027-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10674613
• 关键词: Active Learning; Address; Appointment; Biological; Charge; Clinic; Clinical Competence; Clinical Research; Clinical Sciences; Communities; Competence; Development Plans; Discipline; Doctor' s Degree; Education; Educational Curriculum; Elements; Environment; Extramural Activities; Faculty; Fostering; Funding; Individual; Institution; Lead; Leadership; Learning; Mentors; Mentorship; Process; Program Development; Program Evaluation; Recording of previous events; Research; Research Personnel; Research Project Grants; Role; Science; Structure; Training; Translational Research; career development; community building; educational atmosphere; experience; faculty mentor; improved; innovation; multidisciplinary; novel strategies; peer; programs; recruit; sex; skills; social media; success; translational scientist; visiting scholar

I. INSTITUTIONAL CAREER DEVELOPMENT CORE: Project Summary/Abstract The overall objective of the CCaTS KL2 Institutional Career Development Core is to provide superb training to investigators who can assume leadership roles within multidisciplinary collaborative research teams that conduct outstanding clinical and translational science. The KL2 Program is open to individuals with a doctoral degree in a discipline applicable to clinical and translational research and an existing appointment as Mayo Clinic faculty or under consideration for a Mayo Clinic faculty appointment. After a rigorous selection process, successful applicants and their mentoring team formulate a career development plan based on defined core competencies for clinical and translational science. The plan includes appropriate didactic training; experiential and extramural learning opportunities; and a structured, mentored translational research project. The Specific Aims of this renewal application are to 1) recruit and support a diverse group of Scholars with outstanding potential to lead multidisciplinary, collaborative team science; 2) provide tailored educational experiences based on individual career development needs that include appropriate didactics, experiential activities, and a mentored research experience; and 3) foster a community of Scholars, including partnerships with other career development programs, both within Mayo Clinic and nationally. Key strengths of the KL2 Program include a long history of Program graduates having success as translational scientists, a diverse pool of faculty mentors with strong extramurally funded research programs and a record of mentoring prior Scholars, a large and diverse candidate pool subject to a rigorous selection process, a wide range of curricular options offered without charge, novel strategies to create a positive learning environment for all Scholars, multiple networking and community-building opportunities, options for experiential learning, strong institutional support for the transition to independence after Program completion, and a rigorous evaluation program. Although the KL2 Core has a long history of success, we have identified several opportunities for improvement and innovation, both by crafting new initiatives and by modifying existing program elements as guided by the results of our ongoing rigorous evaluation program. Planned enhancements include new required learning experiences in team science, social media, sex as a biological variable, mentoring (including near-peer cascading mentorship), the hidden curriculum, inclusion and developing a positive working environment for staff, and acting as a visiting scholar. Equipping Scholars with skills addressing these key emerging competencies will prepare them for success as CTS investigators.

I. 机构职业发展核心：项目摘要/摘要 CCaTS KL2 机构职业发展核心的总体目标是为 能够在多学科协作研究团队中担任领导角色的研究人员 开展杰出的临床和转化科学。 KL2 计划向拥有博士学位的个人开放 适用于临床和转化研究的学科学位以及梅奥现有任命 诊所教职人员或正在考虑任命梅奥诊所教职人员。经过严格的选拔过程， 成功的申请者及其指导团队根据明确的核心制定职业发展计划 临床和转化科学的能力。该计划包括适当的教学培训；体验式的 和校外学习机会；以及一个结构化的、指导性的转化研究项目。具体 此续签申请的目的是 1) 招募和支持多元化的杰出学者群体 领导多学科、协作团队科学的潜力； 2）提供量身定制的教育体验 基于个人职业发展需求，包括适当的教学、体验活动和 指导研究经验； 3）培养学者社区，包括与其他职业的伙伴关系 梅奥诊所内部和全国范围内的发展计划。 KL2 项目的主要优势包括项目毕业生在转化方面取得成功的悠久历史 科学家、多元化的教师导师库，拥有强大的校外资助研究项目和记录 指导先前的学者、经过严格选拔过程的庞大且多样化的候选人库、广泛的 免费提供一系列课程选择，为学生创造积极的学习环境的新颖策略 所有学者、多种网络和社区建设机会、体验式学习选择、强大 计划完成后向独立过渡的机构支持，以及严格的评估 程序。 尽管 KL2 Core 有着悠久的成功历史，但我们还是发现了一些改进的机会 和创新，通过制定新举措和修改现有计划要素 我们正在进行的严格评估计划的结果。计划的增强功能包括新的所需学习 在团队科学、社交媒体、性别作为生物变量、指导（包括近同伴）方面的经验 级联辅导）、隐性课程、包容性和为员工营造积极的工作环境 工作人员，并担任访问学者。为学者提供解决这些关键新兴问题的技能 能力将为他们作为 CTS 调查员的成功做好准备。

项目成果

Early Post-Hospitalization Hemoglobin Recovery and Clinical Outcomes in Survivors of Critical Illness: A Population-Based Cohort Study.

• DOI: 10.1177/08850666211069098
• 发表时间: 2022-08
• 期刊: Journal of intensive care medicine
• 影响因子: 3.1

Genetic predictors of chemotherapy-related amenorrhea in women with breast cancer.

乳腺癌女性化疗相关闭经的遗传预测因素。

• DOI: 10.1016/j.fertnstert.2019.05.018
• 发表时间: 2019
• 期刊: Fertility and sterility
• 影响因子: 6.7
• 作者: Ruddy,KathrynJ;Schaid,DanielJ;Partridge,AnnH;Larson,NicholasB;Batzler,Anthony;Häberle,Lothar;Dittrich,Ralf;Widschwendter,Peter;Fink,Visnja;Bauer,Emanuel;Schwitulla,Judith;Rübner,Matthias;Ekici,ArifB;Aivazova-Fuchs,Viktoria

Intraoperative Plasma Transfusion Volumes and Outcomes in Cardiac Surgery.

心脏手术中的术中血浆输注量和结果。

• DOI: 10.1053/j.jvca.2019.12.049
• 发表时间: 2020
• 期刊: Journal of cardiothoracic and vascular anesthesia
• 影响因子: 2.8
• 作者: Smith,MarkM;Kor,DarylJ;Frank,RyanD;Weister,TimothyJ;Dearani,JosephA;Warner,MatthewA
• 通讯作者: Warner,MatthewA

Oxybutynin vs Placebo for Hot Flashes in Women With or Without Breast Cancer: A Randomized, Double-Blind Clinical Trial (ACCRU SC-1603).

奥昔布宁与安慰剂治疗患有或不患有乳腺癌的女性潮热：一项随机、双盲临床试验 (ACCRU SC-1603)。

• DOI: 10.1093/jncics/pkz088
• 发表时间: 2020
• 期刊: JNCI cancer spectrum
• 影响因子: 4.4
• 作者: Leon-Ferre,RobertoA;Novotny,PaulJ;Wolfe,EricG;Faubion,StephanieS;Ruddy,KathrynJ;Flora,Daniel;Dakhil,ChristopherSR;Rowland,KendrithM;Graham,MarkL;Le-Lindqwister,Nguyet;Smith,ThomasJ;Loprinzi,CharlesL
• 通讯作者: Loprinzi,CharlesL

Inflammatory Pseudotumor Resembling a Malignant Pancreatic Disease Process.

类似于恶性胰腺疾病过程的炎性假瘤。

• DOI: 10.21873/anticanres.14978
• 发表时间: 2021
• 期刊: Anticancer research
• 影响因子: 2
• 作者: Kaplan,Jamie;Mangum,Catherine;Shoukry,Mira;Gabriel,Emmanuel
• 通讯作者: Gabriel,Emmanuel