Weight Discrimination and Self-Injurious Thoughts and Behaviors Among Sexual and Gender Minority Adolescents and their Peers

项目摘要/摘要 自杀是早期青少年(即10-14岁)和青少年的第二大死亡原因 近年来，自杀率几乎增加了两倍。自残思想和行为(SITB)，如非 自杀的自我伤害、自杀意念和自杀行为通常首先发生在这一时期。已完成 自杀通常发生在SITB之前，这使得对青春期早期SITB的危险因素的了解成为一种 研究优先。2030年，受歧视的经历被健康人确定为一个关键的社会因素 健康的决定因素。各种类型的歧视，包括性别认同和种族/族裔歧视， 已知与青春期早期的SITB风险较高有关。体重歧视是最严重的 常见类型的歧视在青春期早期，也可能与SITBS有关，但现有的 证据是有限的。性少数和性别少数(SGM)早期青少年，NIH健康差距人口， 大约是非SGM早期青少年经历SITB的四倍，而且他们也更多 可能会报告体重歧视。因此，体重歧视可能是一个特别重要的风险因素 SGM个体中的SITB，但这尚未在早期青少年中进行研究。我提议发表以下讲话 通过对青少年大脑和大脑的数据进行二次分析，这些文献中的重要差距 认知发展研究，这是一项对全国青少年进行的大样本研究，是首批 包括体重歧视、SITBS、SGM身份和其他相关变量的测量。由An指导 改编Meyer的少数民族压力模型，我的具体目的是(1)考察 11-12岁和(2)青少年的体重歧视和SITB决定了这种关联 SGM青少年和异性恋、顺性别的体重歧视和SITBS之间的差异 青少年。此外，作为一个探索性的目的，我将探索两者之间的潜在差异 体重歧视、SGM身份和基于SGM相关压力的SITB、种族/民族歧视，以及 出生时指定的性别。研究结果将为未来预防自杀和促进心理健康的干预措施提供依据 在青少年(特别是SGM青少年)中解决健康的社会决定因素，如 歧视。建议的目标与NINR的预防和健康研究镜片一致 促进、健康的社会决定因素和健康公平。为了促进拟议的研究，我将建立 我在青少年心理健康、SGM健康、数据科学、多层次建模以及 适度分析。在NIH资助的专职跨学科赞助团队的指导下， 和哥伦比亚大学资源丰富的环境，我会筑起坚实的基础，从中走出来 我的长期目标是成为一名独立的、跨学科的护士科学家，在 促进青少年心理健康，特别是在SGM青少年中。

PROJECT SUMMARY/ABSTRACT Suicide is the second leading cause of death among early adolescents (i.e., ages 10-14), and adolescent suicide rates have nearly tripled in recent years. Self-injurious thoughts and behaviors (SITBs), such as non- suicidal self-injury, suicidal ideation, and suicidal behavior, commonly first occur during this period. Completed suicide is often preceded by SITBs, making understanding risk factors for SITBs in early adolescence a research priority. Experiences of discrimination are identified by Healthy People 2030 as a key social determinant of health. Various types of discrimination, including due to sexual identity and race/ethnicity, are known to be associated with higher risk of SITBs in early adolescence. Weight discrimination, among the most common types of discrimination in early adolescence, may also be associated with SITBs, but the existing evidence is limited. Sexual and gender minority (SGM) early adolescents, an NIH health disparities population, are about four times as likely as non-SGM early adolescents to experience SITBs, and they are also more likely to report weight discrimination. Thus, weight discrimination may be a particularly important risk factor for SITBs among SGM individuals, but this has yet to be studied among early adolescents. I propose to address these important gaps in the literature through a secondary analysis of data from the Adolescent Brain and Cognitive Development Study, a study of a large national sample of adolescents that is among the first to include measures of weight discrimination, SITBs, SGM identity, and other pertinent variables. Guided by an adaptation of Meyer’s Minority Stress Model, my specific aims are to (1) examine the association between weight discrimination and SITBs in adolescents ages 11-12 and (2) determine whether the association between weight discrimination and SITBs differs for SGM adolescents and heterosexual, cisgender adolescents. Additionally, in an exploratory aim I will explore potential differences in the association between weight discrimination, SGM identity, and SITBs based on SGM-related stress, racial/ethnic discrimination, and sex assigned at birth. Findings will inform future interventions to prevent suicide and promote mental health among adolescents (especially SGM adolescents) by addressing social determinants of health such as discrimination. The proposed aims align with the NINR’s Research Lenses of Prevention and Health Promotion, Social Determinants of Health, and Health Equity. To facilitate the proposed research, I will build my knowledge and skills in adolescent mental health, SGM health, data science, multilevel modelling, and moderation analysis. With the mentorship of a dedicated and NIH-funded interdisciplinary sponsorship team, and the resource-rich environment of Columbia University, I will build a strong foundation from which to move toward my long-term goal of becoming an independent, interdisciplinary nurse scientist with expertise in promoting adolescent mental health, particularly among SGM adolescents.