Characterizing the relationship between objective physical activity and momentary pain in cognitive behavioral interventions for chronic pain

描述慢性疼痛认知行为干预中客观身体活动与瞬时疼痛之间的关系

基本信息

  • 批准号:
    10679870
  • 负责人:
  • 金额:
    $ 4万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2023
  • 资助国家:
    美国
  • 起止时间:
    2023-08-01 至 2025-07-31
  • 项目状态:
    未结题

项目摘要

PROJECT SUMMARY Chronic pain (CP), a highly prevalent, costly, and disabling biopsychosocial condition, is being increasingly addressed with cognitive behavioral interventions such as Acceptance and Commitment Therapy (ACT) and Cognitive Behavioral Therapy (CBT). Such interventions seek to maximize physical, social, and occupational functioning by changing how one manages pain via addressing pain-related thoughts, beliefs, and behaviors. The current CP literature is limited by the use of between-subject designs and self-report measures that lack ecological validity and may be subject to bias. One component of function, physical activity, is able to be objectively measured in an ecologically valid way using accelerometry. In fact, prior research has combined accelerometry and pain ratings collected using ecological momentary assessment (EMA) to better reflect the real-time, real-world relationship between pain and physical activity. Such research has indicated cross- sectionally a dynamic within-person pain-physical activity relationship. We hypothesize that this dynamic relationship is alterable by cognitive behavioral intervention and seek to examine this research question in Veterans with CP, as they represent an underserved and apt population for CP research given disproportionately high rates of this condition. In Aim 1, we model the relationship between EMA-assessed pain and objective physical activity over a 7-day baseline period, within-person, using parallel latent growth curve modelling (LGCM). We hypothesize that at baseline, the growth trajectories of pain and physical activity will be related such that increases in pain will be associated with decreases in physical activity. In Aim 2, we use multigroup analysis to examine if participation in a cognitive behavioral intervention alters the relationship between the growth trajectories of EMA pain and objective physical activity. We hypothesize that, post- intervention, the relationship between the growth trajectories of pain and physical activity will be significantly altered compared to baseline. In our Exploratory Aim, we conduct follow-up interviews to qualitatively explore how treatment impacts how individuals relate to their pain. Therefore, the proposed research will examine the relationship between pain and physical activity and if and how it changes after cognitive behavioral intervention. The use of structural equation modelling (i.e., LGCM) and qualitative methods will be combined to portray a more complete picture of the experience of CP and treatment. Thus, findings from this study will address existing limitations in the understanding and conceptualization of function in CP, provide information on how to improve function in individuals with CP, and promote the improvement and refinement of cognitive behavioral interventions for the treatment of CP. Importantly, this project will advance the applicant’s long-term goal of becoming an independent clinical researcher committed to applying advanced technological and statistical tools to the improvement of treatments for CP.
项目摘要 慢性疼痛(CP)是一种非常普遍、昂贵和致残的生物心理社会疾病, 认知行为干预,如接受和承诺疗法(ACT), 认知行为疗法(CBT)。这些干预措施寻求最大限度地提高身体、社会和职业 通过解决与疼痛相关的想法、信念和行为来改变一个人管理疼痛的方式。 目前的CP文献受到受试者间设计和自我报告措施的限制, 生态有效性,并可能受到偏见。功能的一个组成部分,身体活动,能够 使用加速度计以生态有效的方式进行客观测量。事实上,先前的研究已经结合了 使用生态瞬时评估(EMA)收集的加速度和疼痛评级,以更好地反映 疼痛和身体活动之间的实时真实关系。这一研究表明,交叉- 分段地动态的人内疼痛-身体活动关系。我们假设这种动态 关系是可以通过认知行为干预来改变的,并试图在 患有CP的退伍军人,因为他们代表了CP研究中服务不足且适合的人群, 不成比例的高发病率。在目标1中,我们建立了EMA评估之间的关系模型 7天基线期内的疼痛和客观体力活动,使用平行潜伏生长法 曲线建模(LGCM)。我们假设在基线时,疼痛和体力活动的增长轨迹 疼痛的增加将与体力活动的减少相关。在目标2中, 使用多组分析来检验参与认知行为干预是否改变了 EMA疼痛的增长轨迹和客观的身体活动之间的关系。我们假设,在- 干预,疼痛和身体活动的增长轨迹之间的关系将显着 与基线相比有所改变。在我们的探索性目标中,我们进行了后续访谈,以定性地探索 治疗如何影响个人与疼痛的关系。因此,拟议的研究将审查 疼痛和体力活动之间的关系,以及在认知行为后疼痛是否以及如何变化 干预使用结构方程模型(即,LGCM)和定性方法相结合, 描绘一个更完整的图片的经验,CP和治疗。因此,这项研究的结果将 解决CP中功能理解和概念化的现有局限性,提供信息 如何改善CP患者的功能,促进认知功能的改善和完善, 行为干预治疗CP。重要的是,该项目将推进申请人的长期 目标是成为一名独立的临床研究人员,致力于应用先进的技术和 统计工具来改善CP的治疗。

项目成果

期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)

数据更新时间:{{ journalArticles.updateTime }}

{{ item.title }}
{{ item.translation_title }}
  • DOI:
    {{ item.doi }}
  • 发表时间:
    {{ item.publish_year }}
  • 期刊:
  • 影响因子:
    {{ item.factor }}
  • 作者:
    {{ item.authors }}
  • 通讯作者:
    {{ item.author }}

数据更新时间:{{ journalArticles.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ monograph.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ sciAawards.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ conferencePapers.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ patent.updateTime }}

Mara Tynan其他文献

Mara Tynan的其他文献

{{ item.title }}
{{ item.translation_title }}
  • DOI:
    {{ item.doi }}
  • 发表时间:
    {{ item.publish_year }}
  • 期刊:
  • 影响因子:
    {{ item.factor }}
  • 作者:
    {{ item.authors }}
  • 通讯作者:
    {{ item.author }}

相似海外基金

Rational design of rapidly translatable, highly antigenic and novel recombinant immunogens to address deficiencies of current snakebite treatments
合理设计可快速翻译、高抗原性和新型重组免疫原,以解决当前蛇咬伤治疗的缺陷
  • 批准号:
    MR/S03398X/2
  • 财政年份:
    2024
  • 资助金额:
    $ 4万
  • 项目类别:
    Fellowship
Re-thinking drug nanocrystals as highly loaded vectors to address key unmet therapeutic challenges
重新思考药物纳米晶体作为高负载载体以解决关键的未满足的治疗挑战
  • 批准号:
    EP/Y001486/1
  • 财政年份:
    2024
  • 资助金额:
    $ 4万
  • 项目类别:
    Research Grant
CAREER: FEAST (Food Ecosystems And circularity for Sustainable Transformation) framework to address Hidden Hunger
职业:FEAST(食品生态系统和可持续转型循环)框架解决隐性饥饿
  • 批准号:
    2338423
  • 财政年份:
    2024
  • 资助金额:
    $ 4万
  • 项目类别:
    Continuing Grant
Metrology to address ion suppression in multimodal mass spectrometry imaging with application in oncology
计量学解决多模态质谱成像中的离子抑制问题及其在肿瘤学中的应用
  • 批准号:
    MR/X03657X/1
  • 财政年份:
    2024
  • 资助金额:
    $ 4万
  • 项目类别:
    Fellowship
CRII: SHF: A Novel Address Translation Architecture for Virtualized Clouds
CRII:SHF:一种用于虚拟化云的新型地址转换架构
  • 批准号:
    2348066
  • 财政年份:
    2024
  • 资助金额:
    $ 4万
  • 项目类别:
    Standard Grant
BIORETS: Convergence Research Experiences for Teachers in Synthetic and Systems Biology to Address Challenges in Food, Health, Energy, and Environment
BIORETS:合成和系统生物学教师的融合研究经验,以应对食品、健康、能源和环境方面的挑战
  • 批准号:
    2341402
  • 财政年份:
    2024
  • 资助金额:
    $ 4万
  • 项目类别:
    Standard Grant
The Abundance Project: Enhancing Cultural & Green Inclusion in Social Prescribing in Southwest London to Address Ethnic Inequalities in Mental Health
丰富项目:增强文化
  • 批准号:
    AH/Z505481/1
  • 财政年份:
    2024
  • 资助金额:
    $ 4万
  • 项目类别:
    Research Grant
ERAMET - Ecosystem for rapid adoption of modelling and simulation METhods to address regulatory needs in the development of orphan and paediatric medicines
ERAMET - 快速采用建模和模拟方法的生态系统,以满足孤儿药和儿科药物开发中的监管需求
  • 批准号:
    10107647
  • 财政年份:
    2024
  • 资助金额:
    $ 4万
  • 项目类别:
    EU-Funded
Ecosystem for rapid adoption of modelling and simulation METhods to address regulatory needs in the development of orphan and paediatric medicines
快速采用建模和模拟方法的生态系统,以满足孤儿药和儿科药物开发中的监管需求
  • 批准号:
    10106221
  • 财政年份:
    2024
  • 资助金额:
    $ 4万
  • 项目类别:
    EU-Funded
Recite: Building Research by Communities to Address Inequities through Expression
背诵:社区开展研究,通过表达解决不平等问题
  • 批准号:
    AH/Z505341/1
  • 财政年份:
    2024
  • 资助金额:
    $ 4万
  • 项目类别:
    Research Grant
{{ showInfoDetail.title }}

作者:{{ showInfoDetail.author }}

知道了