Administrative Core
行政核心
基本信息
- 批准号:10678967
- 负责人:
- 金额:$ 269.24万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2021
- 资助国家:美国
- 起止时间:2021-09-13 至 2026-06-30
- 项目状态:未结题
- 来源:
- 关键词:Artificial IntelligenceAwardBiologicalCardiologyCardiovascular systemClinical DataClinical InvestigatorClinical TrialsCohort StudiesCollaborationsComplexDataData AnalysesData CollectionData Coordinating CenterData ScientistEFRACElectronic Health RecordEnrollmentEnsureEquipmentFellowship ProgramFollow-Up StudiesFundingGenomeGoalsGreenlandHeartHeart failureHuman ResourcesIndustryInfrastructureInstitutionInternationalLaboratoriesLeadershipMedicineMentorsModelingMonitorMulticenter StudiesNational Heart, Lung, and Blood InstituteObservational StudyPatientsPhenotypePostdoctoral FellowProcessProtocols documentationQualifyingRecordsResearchResearch PersonnelResourcesSiteSourceStandardizationSyndromeTrans-Omics for Precision MedicineTranslationsUnited States National Institutes of HealthUniversitiesaugmented intelligencecardiovascular disorder epidemiologyclinical centercomputer sciencedata acquisitiondata repositorydata standardsdesignepidemiology studyexperiencefollow-uphealth datainnovationmHealthoutreachparticipant enrollmentpatient retentionphenomepreservationprogramsprospectiveskillsskills trainingsynergism
项目摘要
PROJECT SUMMARY
The Northwestern HeartShare Data Translation Center (DTC), leverages processes, personnel, and
infrastructure from the Northwestern University (NU) Data Analysis and Coordinating Center (NUDACC), to have
the staffing, equipment, and other resources available to ensure that the Administrative and Outreach Core
meets its goals of (1) designing, implementing, and integrating the HeartShare program components; (2)
coordinating and optimizing the data ascertainment from the electronic health records (EHRs) at the HeartShare
Clinical Centers (CCs); (3) ensuring successful enrollment and retention of heart failure (HF) patients and
controls for the prospective component of HeartShare; (4) supporting a call center and integrating with the Eureka
platform, which will facilitate acquisition of mobile health data and contact with patients; (5) providing consistency
and standardization of data acquisition across the CCs and establishing core laboratories; and (6) developing a
Research Skills Program, which will be modeled after Northwestern’s innovative Computer Science-X (CS-X)
Program, which has successfully bridged the divide between cardiology fellows and post-doctoral data scientists
via integration with Northwestern Bluhm Cardiovascular Institute’s Center for Artificial Intelligence in
Cardiovascular Medicine Fellowship Program. The HeartShare DTC Administrative and Outreach Core also
leverages the resources of the Institute for Augmented Intelligence in Medicine (I.AIM) at Northwestern. The
HeartShare Administrative/Outreach Core is designed to complete the following specific aims. (1) To design,
implement, and coordinate the HeartShare program components to ensure the successful completion of the
retrospective and prospective aspects of the program. We aim to provide guidance to sites and monitor metrics
for HFpEF patient enrollment, engagement, and retention; ensure data consistency and standardization across
sites; and provide administrative, financial, and scientific leadership of HeartShare. (2) To create a state-of-the-
art HeartShare Call Center integrated with the Eureka platform that will facilitate acquisition of mobile health
data, outside records, and longitudinal contact with patients, which will be essential for developing a
comprehensive HeartShare data repository and will facilitate longitudinal follow-up. (3) To create an innovative
Research Skills Program that will provide high-quality mentoring and synergy for early-stage clinical investigators
and data scientists using the successful Northwestern CS-X program as a blueprint.
项目总结
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Sanjiv J Shah其他文献
Semaglutide in obesity-related heart failure with preserved ejection fraction and type 2 diabetes across baseline HbAsub1c/sub levels (STEP-HFpEF DM): a prespecified analysis of heart failure and metabolic outcomes from a randomised, placebo-controlled trial
司美格鲁肽在射血分数保留的肥胖相关心力衰竭和 2 型糖尿病患者中(无论基线糖化血红蛋白水平如何)(STEP-HFpEF DM):一项随机、安慰剂对照试验中心力衰竭和代谢结局的预先指定分析
- DOI:
10.1016/s2213-8587(24)00304-8 - 发表时间:
2025-03-01 - 期刊:
- 影响因子:41.800
- 作者:
Melanie J Davies;Peter van der Meer;Subodh Verma;Shachi Patel;Khaja M Chinnakondepalli;Barry A Borlaug;Javed Butler;Dalane W Kitzman;Sanjiv J Shah;Signe Harring;Afshin Salsali;Søren Rasmussen;Dirk von Lewinski;Walter Abhayaratna;Mark C Petrie;Mikhail N Kosiborod;STEP-HFpEF Trials Committees and Investigators - 通讯作者:
STEP-HFpEF Trials Committees and Investigators
210 - Once-weekly semaglutide in heart failure with preserved ejection fraction and obesity: main results from the STEP-HFpEF trial
- DOI:
10.1016/j.orcp.2024.09.084 - 发表时间:
2024-09-01 - 期刊:
- 影响因子:
- 作者:
Andrew Sindone;Mikhail Kosiborod;Steen Z Abildstrøm;Barry A Borlaug;Javed Butler;Søren Rasmussen;Melanie J Davies;G. Kees Hovingh;Dalane W Kitzman;Marie L Lindegaard;Daniél Vega Møller;Sanjiv J Shah;Marianne Bach Treppendahl;Subodh Verma;Mark C Petrie - 通讯作者:
Mark C Petrie
211 - Once-weekly semaglutide in patients with heart failure with preserved ejection fraction, obesity and type 2 diabetes: main results from the STEP-HFpEF DM trial
- DOI:
10.1016/j.orcp.2024.09.085 - 发表时间:
2024-09-01 - 期刊:
- 影响因子:
- 作者:
Andrew Sindone;Mikhail Kosiborod;Mark C Petrie;Barry A Borlaug;Javed Butler;Melanie J Davies;G. Kees Hovingh;Dalane W Kitzman;Daniél Vega Møller;Marianne Bach Treppendahl;Subodh Verma;Thomas J Jensen;Karoline Liisberg;Marie L Lindegaard;Sanjiv J Shah - 通讯作者:
Sanjiv J Shah
Finerenone and new-onset diabetes in heart failure: a prespecified analysis of the FINEARTS-HF trial
非奈利酮与心力衰竭中新发糖尿病:FINEARTS-HF 试验的预先指定分析
- DOI:
10.1016/s2213-8587(24)00309-7 - 发表时间:
2025-02-01 - 期刊:
- 影响因子:41.800
- 作者:
Jawad H Butt;Pardeep S Jhund;Alasdair D Henderson;Brian L Claggett;Akshay S Desai;Prabhakar Viswanathan;Peter Kolkhof;Patrick Schloemer;Flaviana Amarante;Carolyn S P Lam;Michele Senni;Sanjiv J Shah;Adriaan A Voors;Faiez Zannad;Bertram Pitt;Muthiah Vaduganathan;Scott D Solomon;John J V McMurray;FINEARTS-HF Committees and Investigators - 通讯作者:
FINEARTS-HF Committees and Investigators
Sanjiv J Shah的其他文献
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