Data Analysis Core
Data Analysis Core
批准号:
10701912
负责人:
GEORGE A KUCHEL
金额:
$33.88万
依托单位国家:
美国
项目类别:
财政年份:
2021
资助国家:
美国
项目状态:
未结题
起止时间:
2021-09-30 至 2026-08-31
关键词:
AddressAffectAgeAgingAtlasesBenchmarkingBiologicalBiological MarkersCellsChargeClassificationClinical DataCollaborationsCommon Data ElementCommunitiesComplementComplexComputer AnalysisComputing MethodologiesCytometryDataData AnalysesData Coordinating CenterData SetDevelopmentEnsureEvaluationFAIR principlesFatty acid glycerol estersGenomicsHeterogeneityHistopathologyImageIndividualKidneyLeadLeadershipLinear ModelsMapsMethodsModalityOutputPancreasPathway AnalysisPatientsPatternPlacentaPoliciesPopulationProceduresProcessProteinsProteomicsQuality ControlRLK5-associated protein phosphataseReproducibilityResearchResolutionSamplingSecureSiteStandardizationTestingTissuesUnited States National Institutes of Healthanalysis pipelinecomputerized data processingdata integrationdata managementdata sharingdata sharing networksdeep learningdesignhigh dimensionalityimaging Segmentationneural networkprospectivesenescencesingle nucleus RNA-sequencingsingle-cell RNA sequencingspatial integrationtissue mappingtranscriptometranscriptomics
中文摘要
点击翻译按钮获取中文摘要
英文摘要
The KAPP-Sen Data Analysis core will curate, process, share, and analyze the rich expression
and imaging datasets from the KAPP-Sen projects on kidney, fat, pancreas, and placenta tissues.
Our team (led by Drs. Ucar and Chuang) has broad and extensive expertise in management,
integration, and interpretation of complex high-resolution cellular datasets which will allow us to
centralize the output of the core teams.
The core will be in charge of processing of datasets, analyses and integration, including the
construction of senescence maps.
The Data Analysis Core will interact closely with the Biospecimen Core and the Biological
Analysis Core to systematically receive, assess, organize, and share data from the contributing
sites to ensure FAIR (findability, accessibility, interoperability, and reusability) principles
throughout this project. Pipelines and analysis methods will be developed with a focus on
reproducibility of workflows and robustness of results.
Our team has broad and extensive expertise in management, integration, and interpretation of
complex high-resolution cellular datasets which will allow us to centralize the output of the core
teams. This centralization will maximize the value of the data generated for the KAPP-Sen, for
the overall SenNet, and for the broader research community.
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会议论文
Administrative Core
-
批准号:10376628
-
项目类别:
-
资助金额:$44.98万
-
财政年份:2021
-
负责人:GEORGE A KUCHEL
-
依托单位:
Data Analysis Core
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批准号:10376630
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项目类别:
-
资助金额:$38.3万
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财政年份:2021
-
负责人:GEORGE A KUCHEL
-
依托单位:
Leadership and Administrative Core
-
批准号:10294029
-
项目类别:
-
资助金额:$11.52万
-
财政年份:2021
-
负责人:GEORGE A KUCHEL
-
依托单位:
Bio-Analysis Core
-
批准号:10701913
-
项目类别:
-
资助金额:$138.79万
-
财政年份:2021
-
负责人:GEORGE A KUCHEL
-
依托单位:
Administrative Core
-
批准号:10701908
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项目类别:
-
资助金额:$88.96万
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财政年份:2021
-
负责人:GEORGE A KUCHEL
-
依托单位:
Bio-Analysis Core
-
批准号:10376631
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项目类别:
-
资助金额:$153.67万
-
财政年份:2021
-
负责人:GEORGE A KUCHEL
-
依托单位:
Leadership and Administrative Core
-
批准号:10668311
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项目类别:
-
资助金额:$11.37万
-
财政年份:2021
-
负责人:GEORGE A KUCHEL
-
依托单位:
Role of Senolytics in Lower Urinary Tract Aging and Voiding Disorders
-
批准号:9765752
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项目类别:
-
资助金额:$23.53万
-
财政年份:2019
-
负责人:GEORGE A KUCHEL
-
依托单位:
Detrusor Underactivity as an HCN-mediated Failure of Resilience in Aging
-
批准号:10341070
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项目类别:
-
资助金额:$57.51万
-
财政年份:2019
-
负责人:GEORGE A KUCHEL
-
依托单位:
Role of Senolytics in Lower Urinary Tract Aging and Voiding Disorders
-
批准号:9902307
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项目类别:
-
资助金额:$20.5万
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财政年份:2019
-
负责人:GEORGE A KUCHEL
-
依托单位:
Detrusor Underactivity as an HCN-mediated Failure of Resilience in Aging
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批准号:10556327
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项目类别:
-
资助金额:$57.6万
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财政年份:2019
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负责人:GEORGE A KUCHEL
-
依托单位:
Immune Response to High-Dose vs. Standard Dose Influenza Vaccine
-
批准号:8891347
-
项目类别:
-
资助金额:$38.4万
-
财政年份:2014
-
负责人:GEORGE A KUCHEL
-
依托单位:
Immune Response to High-Dose vs. Standard Dose Influenza Vaccine
-
批准号:8625971
-
项目类别:
-
资助金额:$42.12万
-
财政年份:2014
-
负责人:GEORGE A KUCHEL
-
依托单位:
Immune Response to High-Dose vs. Standard Dose Influenza Vaccine
-
批准号:9339003
-
项目类别:
-
资助金额:$12.3万
-
财政年份:2014
-
负责人:GEORGE A KUCHEL
-
依托单位:
Immune Response to High-Dose vs. Standard Dose Influenza Vaccine
-
批准号:9282386
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项目类别:
-
资助金额:$37.66万
-
财政年份:2014
-
负责人:GEORGE A KUCHEL
-
依托单位:
Immune Response to High-Dose vs. Standard Dose Influenza Vaccine
-
批准号:9069720
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项目类别:
-
资助金额:$38.63万
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财政年份:2014
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负责人:GEORGE A KUCHEL
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依托单位:
Conference Series in Geriatrics: From Bedside to Bench
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批准号:8522110
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项目类别:
-
资助金额:$5.0万
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财政年份:2012
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负责人:GEORGE A KUCHEL
-
依托单位:
Conference Series in Geriatrics: From Bedside to Bench
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批准号:8707920
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项目类别:
-
资助金额:$5.0万
-
财政年份:2012
-
负责人:GEORGE A KUCHEL
-
依托单位:
Conference Series in Geriatrics: From Bedside to Bench
-
批准号:8400001
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项目类别:
-
资助金额:$5.0万
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财政年份:2012
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负责人:GEORGE A KUCHEL
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依托单位:
Pathogenesis of Detrusor Underactivity and Urinary Retention in the Frail Elderly
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批准号:7913513
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项目类别:
-
资助金额:$14.24万
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财政年份:2009
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负责人:GEORGE A KUCHEL
-
依托单位:
海外基金