2023 Cannabinoid Function in the CNS Gordon Research Conference and Gordon Research Seminar

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PROJECT SUMMARY Cannabinoid signaling in the CNS is composed of the types 1 and 2 cannabinoid receptors and their cognate exogenous and endogenous ligands. Cannabinoid signaling is widely distributed throughout the CNS and it is implicated in a wide variety of important neurobiological processes including reward signaling and addiction, regulation of energy homeostasis, learning and memory, motor function, anxiety, and social function. Therefore, understanding the neurobiology of cannabinoid signaling could have broad implications for physiological CNS function and the pathophysiology of neuropsychiatric disorders. The Gordon Research Conference (GRC) on “Cannabinoid Functions in the CNS” and its associated Gordon Research Seminar (GRS) are widely regarded as the best scientific forums in the field of cannabinoid function in the CNS. This GRC meeting has a strong reputation for attracting the most active and renowned scientists in the field and it is an extremely valuable meeting for trainees aiming to become the next generation of cannabinoid neuroscientists. In this application, we request financial support to partially cover expenses for predoctoral and postdoctoral trainees to attend the 2023 and 2025 “Cannabinoid Functions in the CNS” GRS/GRC meetings. The primary aims of this conference are: 1) To provide outstanding scientific programs in the traditions and spirit of the Gordon Research Conferences. These include an emphasis on an environment that fosters inclusivity of a diverse group and the highest level of scientific enquiry in a safe setting. The conference will include cutting-edge unpublished data by leaders in the field; a community atmosphere that fosters informal discussion and stimulates new collaborations; and inclusion of plenary speakers outside of the cannabinoid field who could stimulate new areas of cannabinoid research, and 2) To foster the development of young scientists and trainees in the field. For this aim, a GRS will precede the GRC and will focus on increasing professional networks of young scientists, providing a venue for oral scientific presentation for trainees, and career development seminars. A second approach for this aim will be the implementation of a mentoring system during the GRC to increase 1:1 interactions between trainees and senior scientists in the field. The “Cannabinoid Functions in the CNS” GRS/GRC has several unique qualities including a: 1) focus on the CNS, which is not present at any other cannabinoid-centered meeting; 2) strong emphasis on cutting-edge unpublished data; and 3) continuing commitment to trainees through organization of the GRS, trainee mentoring program, and career development opportunities.