2023 Stem Cells and Cancer Gordon Research Conference and Seminar

2023年干细胞与癌症戈登研究会议暨研讨会

• 批准号: 10683590
• 负责人: Kathrin Plath
• 金额: $ 0.7万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-03-06 至 2024-02-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10683590
• 关键词: Academia; Address; Advanced Development; Area; Automobile Driving; Basic Science; COVID-19 pandemic; Cancer Biology; Cancer Detection; Cellular biology; Collaborations; Communities; Country; Data; Development; Developmental Biology; Disease; Environment; Experimental Models; Feedback; Female; Fertilization; Future; Goals; Growth; Homeostasis; Industry; Italy; Knowledge; Learning; Malignant Neoplasms; Mentors; Mentorship; Metabolic; Metabolism; Methods; Michigan; Minority Groups; Molecular; Molecular Analysis; Neoplasm Metastasis; Organogenesis; Patient Care; Principal Investigator; Productivity; Regenerative Medicine; Request for Proposals; Research; Research Personnel; Role; Science; Scientist; Structure; Technology; Therapeutic; Tissues; Tumor Promotion; Underrepresented Minority; United States National Institutes of Health; Work; cancer cell; cancer initiation; cancer stem cell; cancer therapy; career; catalyst; cell behavior; cell growth; doctoral student; epigenomics; improved; in vivo; interest; meetings; member; neoplastic cell; novel; organ repair; patient prognosis; peer; peer networks; programs; repaired; stem cell aging; stem cell biology; stem cell fate; stem cells; symposium; synergism; tissue regeneration; training opportunity; tumor; tumor eradication; tumor growth; tumor heterogeneity; tumor initiation; tumor progression; tumorigenesis

PROJECT SUMMARY This proposal requests partial support for the eighth Gordon Research Conference on Stem Cells and Cancer, which will take place on May 14-19, 2023 in Lucca (Italy). The goal of this conference is to provide a forum for presentation, discussion and interaction among a diverse, interdisciplinary group of researchers with interests in stem cell biology, development, and cancer. In particular, we wish to highlight how principles taken from development can be used to better understand tumor initiation and metastasis. The meeting is chaired by Dr. Cedric Blanpain (Université Libre de Bruxelles), with Drs. Leanne Jones (UCSF) and Kathrin Plath (UCLA) serving as vice chairs. The planned agenda includes presentations from key leaders in the fields of cancer biology, stem cell biology and regenerative medicine, and thus will attract a highly interdisciplinary group of researchers who do not frequently interact at meetings. This meeting will, therefore, act as a catalyst for new collaborations and cross-fertilization of ideas, which is, of course, a long-term goal of the Gordon Research Conferences. The outstanding scientific program for the meeting highlights the diversity of contributors to this research area (48% of invited speakers are female and/or members of under-represented minority groups) and explores cutting-edge topics of particular interest to the National Institutes of Health (NIH), including but not limited to: developmental mechanisms known to regulate stem cell fate decisions and tissue homeostasis that are usurped for tumor formation, the role of metabolism in regulating stem cells, tissue homeostasis and tumor growth, and emerging therapies to promote tumor cell clearance, eradicate tumor-propagating stem cells and enhance organ repair. Additional speakers will be chosen from the submitted abstracts, with particular consideration given to those investigators from backgrounds traditionally underrepresented in the sciences. The 2023 Gordon Research Conference on Stem Cells and Cancer will also include a Gordon Research Seminar (GRS), a 2-day “pre-meeting” of early career scientists in a highly stimulating and inclusive environment that promotes the open exchange of information and establishment and growth of peer networks. The GRS will be held from May 12-13, 2023 at the same venue in Lucca, and is chaired by Dr. Tugba Topal (Univ. of Michigan) and supported by an organizing committee of three doctoral students: Clara Cano (UCLA), Andrea Pérez González (Université Libre de Bruxelles), and Nicholas Jackson (UCSF). The GRS provides additional opportunities for junior trainees to present their work and receive crucial feedback and mentorship both from their peers and from more established investigators, making this meeting a particularly valuable training opportunity for junior investigators. The specific set of integrated and complementary research topics that will be addressed in the 2023 Stem Cells and Cancer GRS/GRC is distinct from other conferences, and the unique structure of the GRS and GRC provides for productive interactions among scientists and trainees at different career stages in industry and academia who are addressing fundamental questions in the area using different experimental approaches.

项目总结 这项提议要求部分支持第八届戈登干细胞研究会议和 癌症，将于2023年5月14日至19日在意大利卢卡举行。这次会议的目标是提供一个 为不同的跨学科研究人员小组提供演示、讨论和互动的论坛 对干细胞生物学、发育和癌症感兴趣。我们特别要强调的是，原则是如何 可以用来更好地了解肿瘤的起始和转移。会议由以下人员主持 塞德里克·布兰佩恩博士(自由大学)、利安·琼斯博士(加州大学洛杉矶分校)和凯瑟琳·普拉斯博士(加州大学洛杉矶分校) 担任副主席。计划中的议程包括癌症领域主要领导人的演讲 生物学、干细胞生物学和再生医学，因此将吸引一个高度跨学科的小组 不经常在会议上互动的研究人员。因此，这次会议将成为新的 当然，这是戈登研究中心的长期目标 会议。这次会议杰出的科学计划突显了贡献者的多样性。 研究区(48%的受邀发言者是女性和/或代表性不足的少数群体成员)和 探索美国国立卫生研究院(NIH)特别感兴趣的前沿话题，包括但不是 仅限于：已知的调节干细胞命运决定的发育机制和组织动态平衡 被篡夺用于肿瘤形成、新陈代谢在调节干细胞、组织动态平衡和肿瘤中的作用 生长，以及促进肿瘤细胞清除、根除肿瘤增殖干细胞和 加强器官修复。其他发言者将从提交的摘要中选出，特别是 考虑到那些来自传统上在科学界代表性较低的背景的调查人员。这个 2023年戈登干细胞与癌症研究会议还将包括戈登研究研讨会 (GRS)，这是一个为期两天的早期职业科学家在高度刺激和包容的环境中的“预会”， 促进信息的公开交流和同行网络的建立和发展。GRS将是 于2023年5月12日至13日在卢卡的同一地点举行，由Tugba Topal博士(Uni.密歇根州) 并得到了由三名博士生组成的组织委员会的支持：克拉拉·卡诺(加州大学洛杉矶分校)、安德里亚·佩雷斯 González(自由大学)和Nicholas Jackson(加州大学旧金山分校)。GRS提供了额外的 初级实习生有机会介绍他们的工作，并从以下两个方面获得重要的反馈和指导 他们的同行和更成熟的调查人员，使这次会议成为一次特别有价值的培训 初级调查员的机会。一套具体的综合性和互补性研究主题将是 在2023年干细胞和癌症GRS/GRC上发表的演讲有别于其他会议，并且是独一无二的 GRS和GRC的结构为不同领域的科学家和受训者提供了富有成效的互动 在工业界和学术界的职业生涯阶段，他们正在使用不同的方法解决该领域的基本问题 实验方法。