Administrative Core 1

行政核心1：项目摘要/摘要 在孢子框架内，行政核心(核心1)将负责纳入 将孢子调查人员的不同科学学科整合为高度整合的跨学科方法 专注于在翻译黑色素瘤研究方面取得卓越成就，以期对护理产生重大影响 与这种疾病作斗争的病人。该小组的主要目标是确保成功的持续监督 通过专家协调所有项目、核心以及发展和职业提升计划 指导所有活动的财务管理、集中沟通和一般管理。这 CORE将由三名杰出的科学家和知名导师领导，他们目前拥有 在MD Anderson担任行政、研究和/或临床职务，并拥有数十年的 领导经验：Patrick Hwu博士、Elizabeth Grimm博士和Jeffrey E.Lee博士。 行政核心的具体职责包括： ·遵守所有机构、联邦和NIH/NCI的法规和要求。 ·与NCI项目官员和其他NCI工作人员进行沟通和协商，包括准备 所有需要的报告、出版物和其他要求的通信。 ·监测数据质量控制和保证活动，与生物统计和 生物信息学核心(核心3)。 ·优化临床试验工作，包括监测和加强相关的累积进展 孢子临床试验，通过临床试验管理资源(由胡博士和胡博士共同指导) Lee)位于此管理核心内。 ·维持财政和预算责任，包括实行灵活度 通过持续评估计划进展情况和资助理由，酌情选择 分配/重新分配。 ·召开所有必要会议，包括执行委员会、内部和外部咨询 理事会(IAB/EAB)、科学会议、研究会议、讲座和专题讨论会，包括 安排、开发和分发会议材料，并酌情记录会议纪要。 ·协调和资助患者代言人活动。 ·制定和监测招募和留住妇女和少数群体的政策 程序。 ·与其他孢子网站协调，启动和加强合作研究工作，共同主办皮肤癌年度会议，并寻求高潜力发展的机会 研究计划(DRP)和职业提升计划(CEP)申请 合作的调查员。

Adminstrative Core 1: Project Summary/Abstract Within the SPORE framework, the Administrative Core (Core 1) will be responsible for incorporating the diverse scientific disciplines of the SPORE investigators into a highly integrated, interdisciplinary approach focused on achieving excellence in translational melanoma research towards a significant impact on the care of patients battling this disease. The primary goal of this group is to assure the successful continued oversight and coordination of all projects, cores, and developmental and career enhancement programs through expert guidance in fiscal management, centralized communication, and general administration for all activities. This core will be led by three outstanding scientists and well-established mentors who currently hold high-level administrative, research, and/or clinical appointments at MD Anderson and possess decades of combined leadership experience: Drs. Patrick Hwu, Elizabeth Grimm, and Jeffrey E. Lee. Specific responsibilities of the Administrative Core include the following: • Compliance with all institutional, federal, and NIH/NCI regulations and requirements. • Communication and consultation with the NCI project officer and other NCI staff, including preparation of all required reports, publications, and other requested communications. • Monitoring data quality control and assurance activities in conjunction with the Biostatistics and Bioinformatics Core (Core 3). • Optimization of clinical trial efforts, including monitoring and enhancing accrual progress of related SPORE clinical trials, through the Clinical Trials Management Resource (co-directed by Dr. Hwu and Lee) housed within this Administrative Core. • Maintenance of fiscal and budgetary responsibilities, including implementing the SPORE flexibility option as appropriate through ongoing assessments of program progress and justifications for funding allocations/reallocations. • Convening all necessary meetings, including the Executive Committee, Internal and External Advisory Boards (IAB/EAB), scientific meetings, research meetings, lectures, and symposia, including scheduling, development and distribution of meeting materials, and recording minutes as appropriate. • Coordination and funding of Patient Advocate activities. • Establishment and monitoring of policies for recruitment and retention of women and minorities in this program. • Coordination with other SPORE sites to initiate and enhance collaborative research efforts, co-sponsor a yearly Skin Cancer conference, and pursue opportunities for high potential Developmental Research Program (DRP) and Career Enhancement Program (CEP) applications from collaborating investigators.