The Role of Sleep and Community-Level Supports in the Association between Racial Discrimination and Cardiometabolic Health in Black Adolescents

项目总结 黑人青少年在青春期和以后心脏代谢健康不良的风险都会增加 成年期，包括肥胖、高血压和2型糖尿病。这些心脏代谢结果使布莱克 年轻人患心脏病的风险增加，黑人成年人死于心脏病的比例是 白人成年人。种族歧视和睡眠不良被认为是导致心脏新陈代谢的关键因素 健康。虽然对成年人的研究表明，睡眠可能是歧视的一种途径 影响心脏代谢健康，但在青少年中，我们对这一途径的了解存在严重差距。在……里面 相比之下，社区层面的支持可能会保护黑人青年免受压力，包括种族主义的影响 睡眠不佳。然而，对社区支持的保护性的研究主要集中在 心理社会和行为结果。因此，需要进行研究，以检查社区一级的支持，如 防止种族主义对睡眠不良和心脏新陈代谢结果的影响； 睡眠对黑人青年心脏代谢结果的影响。这项拟议的研究的目标是研究 睡眠和社区支持与黑人种族歧视和心脏代谢风险的关系 青少年。该应用程序响应了NHLBI对促进心脏代谢健康的研究的兴趣 生命过程的早期阶段，包括青春期(非HL-21-020)。这些目标将得到解决 通过对具有全国代表性的11-12岁黑人青少年样本的二次分析， 从青少年大脑认知发展(ABCD)研究的第二年随访中，最大的长期- 美国关于大脑发育和儿童健康的学期研究。具体目标是：(1)：测试睡眠 作为黑人青少年中种族歧视和心脏代谢风险之间关系的调解人， 以及(2)测试社区支持作为种族歧视、睡眠和 黑人青少年的心脏代谢风险。解决我们对睡眠和社区如何理解的差距- 水平支持有助于黑人青少年的心脏代谢结果将有助于发展 预防干预措施，以促进黑人一生中长期的心脏新陈代谢健康。 此外，在这份NRSA F31博士前奖学金申请中概述的研究和培训将使我装备自己 拥有必要的技能和支持，成为一名独立的健康差距研究人员， 重点发展和评估以力量为基础的社区一级干预措施，以解决健康差距问题 在服务不足的人群中。

PROJECT SUMMARY Black adolescents are at an increased risk of poor cardiometabolic health during both adolescence and later adulthood, including obesity, hypertension, and type 2 diabetes. These cardiometabolic outcomes put Black youth at an increased risk for the development of heart disease, which kills Black adults at twice the rate of White adults. Racial discrimination and poor sleep are theorized as key factors contributing to cardiometabolic health. While studies in adults suggest that sleep may serve as a pathway through which discrimination influences cardiometabolic health, there is a critical gap in our knowledge of this pathway in adolescents. In contrast, community level-supports may protect Black youth against stressors, including the influence of racism and poor sleep. However, studies of the protective nature of community supports have largely focused on psychosocial and behavioral outcomes. Thus, research is needed to examine community-level supports as protective against the impact of racism on poor sleep and cardiometabolic outcomes; and the impact of poor sleep on cardiometabolic outcomes in Black youth. The goal of the proposed study is to examine the role of sleep and community support in the association of racial discrimination and cardiometabolic risk in Black adolescents. This application is responsive to NHLBI’s interest in research promoting cardiometabolic health in the early stages of the life course, including adolescence (NOT-HL-21-020). The aims will be addressed through secondary analysis of a nationally representative sample of Black adolescents, aged 11-12 years old, from the second-year follow-up of the Adolescent Brain Cognitive Development (ABCD) study, the largest long- term study of brain development and child health in the United States. The specific aims are to: (1): test sleep as a mediator of the association between racial discrimination and cardiometabolic risk in Black adolescents, and (2) test community support as a moderator of the associations among racial discrimination, sleep and cardiometabolic risk in Black adolescents. Addressing gaps in our understanding of how sleep and community- level supports contribute to cardiometabolic outcomes in Black adolescents will aid in the development of prevention interventions to promote long-term cardiometabolic health for Black individuals across the lifespan. Further, the research and training outlined in this NRSA F31 pre-doctoral fellowship application will equip me with the necessary skills and support needed to become an independent health disparities researcher with a focus on developing and evaluating strength-based community-level interventions to address health disparities among underserved populations.