Data Processing and Analysis Core
Data Processing and Analysis Core
批准号:
10688171
负责人:
ARPANA GUPTA
金额:
$30.11万
依托单位国家:
美国
项目类别:
财政年份:
2020
资助国家:
美国
项目状态:
未结题
起止时间:
2020-05-01 至 2025-04-30
关键词:
16S ribosomal RNA sequencingAffectAnatomyArousalBehavioralBig DataBile AcidsBioinformaticsBiologicalBiometryBrainBrain StemBrain imagingCell NucleusCentral Nervous SystemChronicClinicalClinical DataCognitive TherapyComplexConstipationDataData AnalysesData CollectionData SetDiffusionDiseaseEmotionalEmotionsEnsureEstrogensFailureFatty AcidsFunctional Magnetic Resonance ImagingFunctional disorderGenerationsGonadal Steroid HormonesHormonesHumanImageImaging technologyIndividualInformation SystemsIrritable Bowel SyndromeKnowledgeLinkMagnetic Resonance ImagingMeasuresMediatingMenopausal StatusMenopauseMenstruationMetagenomicsMethodologyMissionModelingMolecularMonitorMultimodal ImagingMultiomic DataNeurobiologyPainPathway interactionsPhasePhenotypeProtocols documentationPublic HealthQuality ControlResearch PersonnelResolutionRestRoleSeveritiesSex DifferencesShotgunsStructureSymptomsSystemTechnologyTestingTryptophanVolatile Fatty AcidsWritingbiological systemscomputerized data processingdata acquisitiondata integrationdesignfrontiergut microbiomemetabolomicsmicrobiomemicrobiome analysismicrobiotamultimodalitymultiple omicsmultisensoryneuroimagingnew therapeutic targetnovel diagnosticspsychosocialresponsesexspectrographstatisticstherapy outcometooltreatment response
中文摘要
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英文摘要
ABSTRACT
The proposed Data Processing and Analysis Core (DPAC) will provide the advanced microbiome,
metabolomics and neuroimaging tools and technologies necessary to analyze the interactions of
neurobiological and molecular mechanisms underlying the brain-gut-microbiome axis, sex differences in this
system, the influence of hormones on systems, and sex related differences in the effect of cognitive behavioral
therapy on emotion and salience circuits. Elucidation of brain-gut-microbiome pathways cannot be achieved by
analysis of microbiome and neuroimaging data sets in isolation. Integration of these distinctive `omics data sets
to find biologically meaningful relationships, represents a frontier in bioinformatics that will be critical to identify
novel diagnostic and therapeutic targets for IBS.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Social Isolation and Discrimination as Stressors Influencing Brain-Gut Microbiome Alterations among Filipino and Mexican American
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批准号:10850290
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项目类别:
-
资助金额:$5.57万
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财政年份:2023
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负责人:ARPANA GUPTA
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依托单位:
Social Isolation and Discrimination as Stressors Influencing Brain-Gut Microbiome Alterations among Filipino and Mexican American
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批准号:10541209
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项目类别:
-
资助金额:$76.55万
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财政年份:2021
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负责人:ARPANA GUPTA
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依托单位:
Social Isolation and Discrimination as Stressors Influencing Brain-Gut Microbiome Alterations among Filipino and Mexican American
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批准号:10376764
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项目类别:
-
资助金额:$77.44万
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财政年份:2021
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负责人:ARPANA GUPTA
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依托单位:
Role of the Gut Microbiome in Reward Network Alterations in Obesity
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批准号:9895068
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项目类别:
-
资助金额:$11.7万
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财政年份:2020
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负责人:ARPANA GUPTA
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依托单位:
Data Processing and Analysis Core
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批准号:10461216
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项目类别:
-
资助金额:$30.24万
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财政年份:2020
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负责人:ARPANA GUPTA
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依托单位:
Role of Inflammatory Processes in Reward Network Alterations in Obesity
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批准号:9897563
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项目类别:
-
资助金额:$20.29万
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财政年份:2016
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负责人:ARPANA GUPTA
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依托单位:
Role of Inflammatory Processes in Reward Network Alterations in Obesity
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批准号:9108126
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项目类别:
-
资助金额:$19.03万
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财政年份:2016
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负责人:ARPANA GUPTA
-
依托单位:
Role of Inflammatory Processes in Reward Network Alterations in Obesity
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批准号:9265841
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项目类别:
-
资助金额:$20.25万
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财政年份:2016
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负责人:ARPANA GUPTA
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依托单位:
海外基金