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Data Processing and Analysis Core

Data Processing and Analysis Core
数据处理与分析核心
批准号:
10688171
负责人:
ARPANA GUPTA
金额:
$30.11万
依托单位国家:
美国
项目类别:
财政年份:
2020
资助国家:
美国
项目状态:
未结题
起止时间:
2020-05-01 至 2025-04-30

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英文摘要
ABSTRACT The proposed Data Processing and Analysis Core (DPAC) will provide the advanced microbiome, metabolomics and neuroimaging tools and technologies necessary to analyze the interactions of neurobiological and molecular mechanisms underlying the brain-gut-microbiome axis, sex differences in this system, the influence of hormones on systems, and sex related differences in the effect of cognitive behavioral therapy on emotion and salience circuits. Elucidation of brain-gut-microbiome pathways cannot be achieved by analysis of microbiome and neuroimaging data sets in isolation. Integration of these distinctive `omics data sets to find biologically meaningful relationships, represents a frontier in bioinformatics that will be critical to identify novel diagnostic and therapeutic targets for IBS.
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Social Isolation and Discrimination as Stressors Influencing Brain-Gut Microbiome Alterations among Filipino and Mexican American
Social Isolation and Discrimination as Stressors Influencing Brain-Gut Microbiome Alterations among Filipino and Mexican American
Social Isolation and Discrimination as Stressors Influencing Brain-Gut Microbiome Alterations among Filipino and Mexican American
Role of the Gut Microbiome in Reward Network Alterations in Obesity
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