Medical Scientist National Research Service Award

医学科学家国家研究服务奖

• 批准号: 10703834
• 负责人: Marcus Ramsay Clark
• 金额: $ 127.72万
• 依托单位: UNIVERSITY OF CHICAGO
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-07-01 至 2028-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10703834
• 关键词: Medical; National Research Service Awards; Scientist

PROJECT SUMMARY The mission of The University of Chicago (UChicago) Medical Scientist Training Program (MSTP) is to train the next generation of clinician-scientists for impactful careers in the biomedical sciences. Impact is broadly defined as: providing fundamental insights into disease and relevant biological mechanisms, leading or making substantial contributions to translational efforts to identify better therapies and/or filling leadership roles that will determine how limited resources can best be used to improve human health. Our overall objective is to train outstanding and self-directed clinician scientists who can formulate and answer biologically and medically- important questions. To ensure the greatest impact, our program must reflect the diversity of the U.S. population in both who it trains and who it serves. To accomplish our mission and overall objective, we defined 15 specific and measurable objectives that stress the technical, operational and professional skills that support science identity and self-efficacy and are critical for a successful career as an independent biomedical investigator. Two unique features of the program enable our mission and provide an optimal training environment for the development of clinician-scientists. First, we are our own graduate program, the Interdisciplinary Scientist Training Program (ISTP). The ISTP allows integration of graduate and medical school classes in MS1, development of tailored curricula for each trainee, coordination across training transitions and uniform oversight and expectations during the graduate phase. Second, most trainees pursue a 1-4-3 progression of study rather than the traditional 2-4-2 progression. While trainees may pursue a 2-4-2, the 1-4-3 provides a continuous and in-depth graduate experience where trainees become well-trained scientists who can propose and rigorously test hypotheses. The 1-4-3 also provides a seamless transition between the preclinical and clinical phases which facilitates overall success in medical school. Multiple programmatic features ensure that fundamental scientific and clinical knowledge are interwoven to foster the development of impactful clinician-scientists. The UChicago MSTP enjoys sustained and substantial University financial backing including generous direct investment and support of facilities that cultivate innovative science. We are requesting 25 training slots to supplement University investments to support trainees for six of the typical eight years they spend in the MSTP. This requested investment by the NIH would constitute only 13% of total anticipated cost for our MSTP. We anticipate a program size of approximately 80 trainees and expect, based on our track record, that our trainees will contribute significantly to the U.S. biomedical enterprise.

项目摘要 芝加哥大学（UChicago）医学科学家培训计划（MSTP）的使命是培养 下一代临床科学家在生物医学科学的影响力的职业生涯。影响广泛 定义为：提供对疾病和相关生物机制的基本见解， 为翻译工作做出实质性贡献，以确定更好的疗法和/或填补领导角色， 确定如何最好地利用有限的资源来改善人类健康。我们的总体目标是训练 杰出和自我指导的临床科学家谁可以制定和回答生物学和医学- 重要的问题为了确保最大的影响，我们的计划必须反映美国的多样性。 它所训练的人和它所服务的人。为了完成我们的使命和总体目标，我们定义了 15个具体和可衡量的目标，强调技术、业务和专业技能， 科学身份和自我效能，是一个成功的职业生涯作为一个独立的生物医学的关键 调查员该计划的两个独特功能使我们的使命，并提供最佳的培训 为临床科学家的发展创造环境。首先，我们是我们自己的研究生课程， 跨学科科学家培训计划（ISTP）。ISTP允许研究生和医学的整合 MS 1的学校课程，为每个受训者制定量身定制的课程，协调培训 过渡和统一的监督和期望在毕业阶段。其次，大多数学员追求的是 1-4-3的学习进度，而不是传统的2-4-2的进度。虽然学员可以追求2-4-2， 1-4-3提供了一个持续和深入的研究生经验，学员成为训练有素的科学家 能够提出并严格检验假设的人1-4-3还提供了一个无缝过渡之间的 临床前和临床阶段，促进在医学院的整体成功。多方案 功能确保基础科学和临床知识交织在一起，以促进发展 有影响力的临床科学家芝加哥大学MSTP享有持续和大量的大学财政 支持，包括慷慨的直接投资和支持培养创新科学的设施。我们 要求25个培训名额，以补充大学的投资，以支持典型的8个培训名额中的6个 他们在MSTP中花费的时间。美国国立卫生研究院要求的投资仅占总投资的13 我们的MSTP的预期成本。我们预计计划规模约为80名学员，并预计，基于 在我们的业绩记录中，我们的学员将为美国生物医学企业做出重大贡献。