Advanced Visualization Branch

高级可视化分支

• 批准号: 10706199
• 负责人: Patricia Brennan
• 金额: $ 71.25万
• 依托单位: NATIONAL INSTITUTE OF NURSING RESEARCH
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10706199
• 关键词: 3-Dimensional; Acceleration; Age; American; Appointment; Behavior; Behavior assessment; Big Data; Calendar; Care given by nurses; Chronic; Chronic Disease; Clinical; Clinical Nursing; Clinical Research; Cognition; Cognitive; Collaborations; Common Data Element; Communities; Complement; Complex; Computer software; Computers; Contractor; Country; Custom; Data; Data Analyses; Development; Diet; Disease; Engineering; Environment; Environmental Risk Factor; Evaluation; Fatigue; Fatty acid glycerol esters; Food; Frozen Sections; Future; Geography; Goals; Healthcare; Home; Home Care Services; Home environment; Immersion; Individual; Lead; Learning; Locomotion; Manuscripts; Measurement; Measures; Medical; Medical Informatics; Medication Management; Minor; Modification; Motion; Movement; Music; National Institute of Drug Abuse; National Institute on Minority Health and Health Disparities; Noise; Nurses; Outcome Assessment; Participant; Patient Recruitments; Patients; Performance; Persons; Phase; Play; Population; Principal Investigator; Process; Protocols documentation; Research; Research Personnel; Research Project Grants; Role; Schedule; Scientist; Self Care; Self Management; Self Medication; Slide; Sodium; Sodium-Restricted Diet; Sorting; Technology; Time; Training; United States National Aeronautics and Space Administration; United States National Institutes of Health; User-Computer Interface; Visualization; Waiting Lists; Woman; Work; base; behavior measurement; biomedical informatics; cognitive load; cognitive process; design; dietary; dietary restriction; digital; disability; experience; falls; human subject; improved; informant; instrument; instrumental activity of daily living; interest; meetings; men; nutrition; phase 2 study; pill; posters; programs; racial and ethnic; racial diversity; recruit; side effect; social health determinants; sound; square foot; standard measure; statistics; sugar; summer internship; telework; tool; usability; virtual; virtual environment; virtual reality environment

The purpose of the AVB is to improve self-management among persons with complex chronic disease. The primary research instrument we use is immersive virtual reality (IVR, VR), which allows the participant to experience familiar environments and conduct self-management activities in a highly controlled space that allows for precise measurement of movement and assessment of the cognitive and behavioral task effort. To this aim, we develop virtual environments that depict scenes familiar to the lay person (homes, grocery stores) and insure that these are accessible to a broad range of individuals including those with limited digital experience, across a broad age-range, diverse backgrounds, and potentially those with some cognitive or physical limitation. Now that we have demonstrated that the virtual shopping environment and interface works for a broad range of individuals, we will submit additional protocols evaluating specific aspects of self-management. We completed our first study over a period of 10 weeks and are in the process of analyzing the data collected from the study and are in the process of preparing presentations and manuscripts to disseminate the findings. The results of our first study support our aims to create accessible experiences to a broad range of participants, even those with minor disabilities. Phase 2 of the study has been postponed to Fall, 2022. Phase 2 will explore participants abilities to demonstrate compliance with dietary restrictions, including food choice selection and compliance with sodium restrictions. We already have an extensive wait-list of individuals wanting to participate. For outcome assessment we employ standard measures of cognitive burden (VAS-Cognition) and task burden (NASA TLX). We empty observational measures such as time to perform tasks, duration of IVR immersion, and simulator sickness assessment to evaluate the acceptability of the IVR experience on participants. We applied the same multipurpose immersive VR platform to create a second environment to assess participants abilities to perform medication self management within the home environment. As correctly placing pills in a pillbox is a complex cognitive process, we have created a simple version of the task to identify individual cognitive factors that may contribute to errors in pill sorting. Our current environment enables us to determine if individuals can visually differentiate pill types, match to a calendar showing proper pill placement and then determining how quickly this information is processed. A subset of participants completed the pillbox task during phase 1 of the protocol. Each participant successfully learned and performed the task with minimal difficulty. The pillbox task will be used as a performance decrement indicator in phase 2 of our cognitive fatigue study. This task and virtual environment are a jumping off point for a future protocol evaluating the cognitive and environmental factors influencing medication management. Our lab has a strong commitment to training, including hosting two post-bac trainees (Sara Flash and Allyson Ferguson) and one summer intern (Nikhil Pradeep). Trainees participate in all phased of design and evaluation of our IVR environments, and gain additional experiences using big data, and supporting common data elements work. Sara Flash worked closely with our nurse consultant, Denise Goldsmith, to evaluate locomotion in IRV space (poster presented at NIH) and completed NIH presentations based on data extracted from the All of Us project. We presented posters at the American Medical Informatics Association annual meeting, thus integrating VR into the biomedical informatics community. Our trainees each have an experience proposing and answering questions using the All of Us Researchers workbench. The data provided a platform for training in research statistics using existing data and scientific presenting. Additionally, our studies have included data that supports NINR common data elements and initiatives including the social determinants of health and PROMIS measures. We are interested in extending our research through collaborations and are exploring options with NIMHD and NIDA. Our current staff includes the Principal Investigator, two post-bac trainees, and 3 remote contractors including a full-time graphic designer, a part-time engineer, and a part-time clinical nurse. Our team is geographically spread across the country in different time zones and varying work schedules. We lost our lead scientist and have been unsuccessful in recruiting a computer engineer. We have temporarily paused engaging human subjects in our research and will resume as soon as our staffing complement is complete. We will add an additional post-bac (Will Thompson) to aid in the next phase of research protocols and to increase our training efforts. Despite a small staff, under mostly remote telework, the AVB has moved forward with a complex research agenda and has completed proof of concept that immersive technology has potential to be a useful tool in the healthcare arena. We anticipate an acceleration of our scientific program over the next year.

AVB的目的是改善患有复杂慢性病的人的自我管理。我们使用的主要研究工具是沉浸式虚拟现实（IVR，VR），它允许参与者体验熟悉的环境，并在高度受控的空间中进行自我管理活动，从而可以精确测量运动并评估认知和行为任务的努力。 为了实现这一目标，我们开发了虚拟环境，描绘了外行人（家庭，杂货店）熟悉的场景，并确保这些场景可以被广泛的个人访问，包括那些数字经验有限的人，跨越广泛的年龄范围，不同的背景，以及可能有一些认知或身体限制的人。既然我们已经证明了虚拟购物环境和界面适用于广泛的个人，我们将提交额外的协议，评估自我管理的具体方面。 我们在10周内完成了第一项研究，目前正在分析从研究中收集的数据，并正在编写报告和手稿，以传播研究结果。我们第一项研究的结果支持我们的目标，即为广泛的参与者创造无障碍体验，即使是那些有轻微残疾的人。该研究的第二阶段已推迟至2022年秋季。 第二阶段将探索参与者证明遵守饮食限制的能力，包括食物选择和遵守钠限制。我们已经有一个广泛的等待名单的个人希望参加。 对于结果评估，我们采用认知负担（VAS-认知）和任务负担（NASA TLX）的标准测量。 我们空的观察措施，如执行任务的时间，IVR沉浸的持续时间，和模拟器疾病评估，以评估参与者的IVR体验的可接受性。 我们应用相同的多用途沉浸式VR平台来创建第二个环境，以评估参与者在家庭环境中进行药物自我管理的能力。由于正确地将药丸放入药丸盒是一个复杂的认知过程，我们创建了一个简单版本的任务，以识别可能导致药丸分类错误的个体认知因素。我们目前的环境使我们能够确定个人是否可以在视觉上区分药丸类型，匹配显示正确药丸放置的日历，然后确定处理这些信息的速度。一部分参与者在方案的第1阶段完成了药盒任务。每个参与者都成功地学习并以最小的难度完成了任务。在我们的认知疲劳研究的第2阶段，将使用药盒任务作为性能递减指标。 这个任务和虚拟环境是一个跳跃点，为未来的协议评估认知和环境因素影响药物管理。 我们的实验室对培训有很强的承诺，包括接待两名后bac学员（Sara Flash和Allyson Ferguson）和一名暑期实习生（Nikhil Pradeep）。 学员参与我们IVR环境的设计和评估的所有阶段，并获得使用大数据和支持常见数据元素工作的额外经验。Sara Flash与我们的护士顾问Denise金匠密切合作，评估IRV空间中的运动（在NIH展示的海报），并根据从All of Us项目中提取的数据完成了NIH演示。我们在美国医学信息学协会年会上展示了海报，从而将VR整合到生物医学信息学领域。我们的每个学员都有使用All of Us Researchers工作台提出和回答问题的经验。 这些数据为利用现有数据和科学列报进行研究统计培训提供了一个平台。此外，我们的研究还包括支持NINR共同数据要素和举措的数据，包括健康的社会决定因素和PROMIS措施。我们有兴趣通过合作扩展我们的研究，并正在探索与NIMHD和NIDA的选择。 我们目前的工作人员包括主要研究者，两名后bac学员和3名远程承包商，包括全职平面设计师，兼职工程师和兼职临床护士。我们的团队在地理上分布在不同的时区和不同的工作时间表。 我们失去了我们的首席科学家，一直未能招募到一名计算机工程师。我们已经暂时停止了在我们的研究中与人类受试者的接触，一旦我们的人员补充完成，我们就会恢复。 我们将增加一个额外的后bac（将汤普森），以帮助在下一阶段的研究方案，并增加我们的培训工作。尽管工作人员很少，但在大多数远程工作的情况下，AVB已经推进了一项复杂的研究议程，并完成了概念验证，即沉浸式技术有可能成为医疗保健竞技场中的有用工具。我们预计明年我们的科学计划将加速进行。