Receptor kinase signal integration in stem cell maintenance and development.
Receptor kinase signal integration in stem cell maintenance and development.
批准号:
10797759
负责人:
Zachary Luke Nimchuk
金额:
$3.85万
依托单位国家:
美国
项目类别:
财政年份:
2016
资助国家:
美国
项目状态:
未结题
起止时间:
2016-08-04 至 2027-05-31
关键词:
AnimalsCell MaintenanceDesiccationDevelopmentDrynessEquipmentEukaryotaFundingGenesImagePeptide Signal SequencesPeptidesPhosphotransferasesPlant PreparationsPlant StemsPlantsPlayProcessRegulationRoleScanning Electron MicroscopySignal TransductionSystemTissue SampleTissuesinstrumentationmutantplant growth/developmentreceptorstem cell nichestem cells
中文摘要
该项目正在为徕卡EM CPD300自动临界点干燥申请资金
用于扫描电子显微镜的植物组织样品制备系统。这项建议
支持R35GM119614,旨在了解CLE肽信号在干细胞中的作用
植物的调控和发展。扫描电子显微镜在超微结构分析中发挥了重要作用。
植物组织在这一项目中,然而缺乏临界点干燥设备,限制了
可以分析的组织类型的范围。因此,徕卡EM CPD300将启用成像
以快速和高产量的方式快速和容易干燥的精致植物组织,并将
协助分析CLE多肽在植物发育中所起的作用。
英文摘要
The project is requesting funds for a Leica EM CPD300 automated Critical Point Drying
system for preparing plant tissue samples for Scanning Electron Microscopy. This proposal
supports R35GM119614 which aims to understand the role of CLE peptide signaling in stem cell
regulation and development in plants. SEM has been instrumental in ultrastructural analysis of
plant tissues in this project, however the lack of critical point drying equipment has limited the
scope of tissue types that can be analyzed. As such Leica EM CPD300 will enable the imaging
of delicate and easily desiccated plant tissues rapidly and in a high throughput manner and will
assist the analysis of the processes CLE peptides play in plant development.
期刊论文(11)
专著(0)
科研奖励(0)
会议论文
DOI:
10.1038/s41477-022-01134-w
发表时间:
2022-04-14
期刊:
NATURE PLANTS
影响因子:
18
作者:
[DeFalco, Thomas A., Anne, Pauline, Nimchuk, Zachary L.]
通讯作者:
Nimchuk, Zachary L.
DOI:
10.1038/s41588-019-0389-8
发表时间:
2019-05-01
期刊:
NATURE GENETICS
影响因子:
30.8
作者:
[Rodriguez-Leal, Daniel, Xu, Cao, Lippman, Zachary B.]
通讯作者:
Lippman, Zachary B.
Receptor kinase signal integration in stem cell maintenance and development.
-
批准号:10406499
-
项目类别:
-
资助金额:$38.22万
-
财政年份:2016
-
负责人:Zachary Luke Nimchuk
-
依托单位:
Receptor kinase signal integration in stem cell maintenance
-
批准号:9326323
-
项目类别:
-
资助金额:$37.51万
-
财政年份:2016
-
负责人:Zachary Luke Nimchuk
-
依托单位:
Receptor kinase signal integration in stem cell maintenance and development.
-
批准号:10618408
-
项目类别:
-
资助金额:$38.2万
-
财政年份:2016
-
负责人:Zachary Luke Nimchuk
-
依托单位:
海外基金