Mouse Phenotyping Informatics Infrastructure - Data acquisition, integration, analysis and translation of high throughput mammalian phenotyping data.

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PROJECT SUMMARY The International Mouse Phenotyping Consortium (IMPC) is a critical resource for biomedical research providing novel gene-phenotype associations for genes with little or no known function, supplying strains for thousands of mechanistic studies and delivering integration with genomic, phenomic and human disease- relevant information providing improved understanding into the underlying causes of rare and common disease. This project aims to improve the FAIR-ness and TRUST-worthiness of the resource by: ● Improving resource identification with a focus on the actual model organisms produced by the consortium ● Increasing the exposure and adoption of the resource by publishing an IMPC knowledge graph ● Developing a proof of concept to capture cost metrics for long-term sustainability