Mentored Training in Molecular Epidemiology of Chronic Kidney Disease in Diverse Populations

不同人群慢性肾脏病分子流行病学指导培训

• 批准号: 10799234
• 负责人: Nora Franceschini
• 金额: $ 6.92万
• 依托单位: UNIV OF NORTH CAROLINA CHAPEL HILL
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-15 至 2028-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10799234
• 关键词: Adult; Affect; American Heart Association; American Indians; Area; Atherosclerosis Risk in Communities; Award; Black Populations; Cardiovascular Diseases; Cause of Death; Cessation of life; Chronic Kidney Failure; Cohort Studies; Data; Dedications; Developing Countries; Disease; Diverse Workforce; Education; Educational process of instructing; Enrollment; Epidemiologist; Epidemiology; Epigenetic Process; Etiology; Faculty; Funding; Genetic; Genetic Research; Goals; Grant; Heart; Hispanic Community Health Study/Study of Latinos; Hispanic Populations; Individual; International; Intervention; Kidney; Latino Population; Leadership; Learning; Mentors; Mentorship; Methods; Molecular; Molecular Epidemiology; Nephrology; North Carolina; Paper; Population; Population Heterogeneity; Positioning Attribute; Postdoctoral Fellow; Prevention; Principal Investigator; Proteomics; Public Health; Publications; Research; Research Personnel; Research Project Grants; Research Support; Risk; Risk Factors; Science; Scientist; Societies; Source; Therapeutic; Time; Training; Trans-Omics for Precision Medicine; Underrepresented Populations; United States National Institutes of Health; Universities; Women' s Health; Work; Writing; agricultural community; base; burden of illness; cardiovascular disorder epidemiology; career; design; disability; epidemiology study; experience; genetic epidemiology; genetic variant; graduate school; graduate student; improved; meetings; member; metabolomics; molecular marker; multidisciplinary; next generation; pre-doctoral; premature; programs; recruit; skills; tool; transcriptome

ABSTRACT Chronic kidney disease affects one in seven U.S. adults and is a leading cause of death and disability. Chronic kidney disease has a substantial impact on U.S. diverse populations, including Blacks, Hispanics/Latinos and American Indians. Research on the epidemiology and molecular risk factors contributing to chronic kidney disease in diverse populations is much needed to guide public health prevention and interventions, and to develop therapeutic tools for clinicians to effectively treat the disease. This K26 application will support protected time for Nora Franceschini, MD MPH, to mentor junior investigators from underrepresented groups in science on molecular epidemiology research of chronic kidney disease in diverse populations. Dr. Franceschini is a nephrologist and an epidemiologist with a 20-year experience conducting multidisciplinary studies in chronic kidney disease and mentoring graduate students and early-stage investigators, including those from underrepresented groups. Dr. Franceschini has developed a strong National Institutes of Health supported research program on chronic kidney disease at the University of North Carolina focused on diverse populations. This research program offers multiple opportunities for trainees to learn rigorous research skills in state-of-art approaches for research in the epidemiology, molecular epidemiology and biomarkers of chronic kidney disease. Proposed activities and enhanced mentoring skills support the goals to increase high-quality mentoring for the next generation of scientists (including URGs) in chronic kidney disease research within her research program.

摘要 慢性肾脏疾病影响七分之一的美国成年人，是死亡和残疾的主要原因。慢性 肾脏疾病对美国不同人群有重大影响，包括黑人、西班牙裔/拉丁裔和 美洲印第安人慢性肾脏病的流行病学及分子危险因素研究 非常需要在不同人群中预防疾病，以指导公共卫生预防和干预， 为临床医生开发治疗工具，以有效治疗疾病。此K26应用程序将支持 保护诺拉弗兰切斯基尼，医学博士公共卫生硕士的时间，指导初级研究人员从代表性不足的群体， 在不同人群中开展慢性肾脏病分子流行病学研究的科学。弗兰切斯基尼博士 是一位肾脏病学家和流行病学家，在以下方面进行了20年的多学科研究： 慢性肾脏疾病和指导研究生和早期研究人员，包括来自 代表性不足的群体。Franceschini博士已经建立了一个强大的国立卫生研究院支持 北卡罗来纳州大学的慢性肾脏疾病研究项目侧重于 人口。该研究计划为学员提供多种机会，学习严格的研究技能， 流行病学、分子流行病学和生物标志物研究的最新方法 肾病拟议的活动和增强的辅导技能支持提高高质量的目标， 指导下一代科学家（包括URG）在她的慢性肾脏疾病研究 研究计划。