Interpersonal Stress, Social Media, and Risk for Adolescent Suicidal Thoughts and Behaviors

人际压力、社交媒体以及青少年自杀想法和行为的风险

• 批准号: 10815112
• 负责人: RANDY PATRICK AUERBACH
• 金额: $ 95.72万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-14 至 2028-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10815112
• 关键词: 17 year old; Address; Adolescent; Age; Amygdaloid structure; Anterior; Biological; Biological Markers; Biological Process; Buffers; Cause of Death; Characteristics; Chronic; Clinical; Clinical assessments; Coupling; Data; Development; Emergency department visit; Enrollment; Evaluation; Event; Exhibits; Exposure to; Feedback; Feeling suicidal; Functional Magnetic Resonance Imaging; Future; Generations; Goals; Hair; Hate; Hospitalization; Hydrocortisone; Insula of Reil; Interruption; Interview; Lead; Life; Link; Measures; Mediating; Mental disorders; Methods; Natural Language Processing; Pathway interactions; Patient Self-Report; Persons; Physiological; Physiological Processes; Predisposition; Process; Public Health; Recording of previous events; Reporting; Research; Risk; Risk Behaviors; Risk Factors; Sampling; Severities; Social Environment; Social Network; Social Processes; Social support; Speech; Stress; Suicide; Suicide attempt; Testing; Time; Victimization; Violence; Youth; adolescent suicide; digital; experience; follow up assessment; high risk; hypothalamic-pituitary-adrenal axis; ideation; innovation; neural; neural correlate; neural network; novel; peer; preventive intervention; recruit; response; social; social capital; social media; suicidal; suicidal adolescent; suicidal behavior; suicidal risk; suicide rate; temporal measurement; theories

Project Summary Over the past 15 years, suicide rates among adolescents have increased ~60%. Recently, problematic social media use has been linked to the emergence of suicidal thoughts and behaviors (STB), perhaps reflecting greater interpersonal stress exposure. Understanding the type, timing, and severity of interpersonal stress exposure is critical to understand STB risk, which requires carefully characterizing exposures present in their digital lives through a deep interrogation of real-time interactions within social media. In line with the Stress Generation Framework, adolescents experiencing psychiatric disorders possess characteristics that increase the occurrence of interpersonal stress, which may include negative social media exposures. Accordingly, this project will identify social neural susceptibilities that may increase the occurrence of negative social media exposures and examine physiological processes that are impacted by negative social media exposures over time. Our study will include adolescents ages 14-17 (N=300), which will be oversampled for youth at high risk for suicide (n=200), defined as STB in the past 3 months and/or a past-year suicide attempt. Additionally, we will recruit adolescents with psychiatric disorders but without a lifetime history of STB (n=100), providing an opportunity to identify biological markers and temporally refined social media exposures that characterize risk for STB as opposed to identifying risk factors that associate with psychiatric disorders more broadly. Comprehensive clinical assessments will be completed at baseline, and additionally, we will probe past-year user-generated content to assess dynamic changes in negative exposures to characterize core interpersonal processes across social media platforms, including: (a) online victimization (e.g., harassment, hate speech), (b) reduced social capital (e.g., reduced social network size), and (c) reduced social support (e.g., reduced engagement, reciprocity of messaging). We also will collect baseline fMRI neural responses characterizing social processes and assess chronic HPA axis activity. At the 2-, 4-, and 6-month follow-up assessments, interviews, social media data, HPA axis activity, and self-reports will be re-assessed. The overarching goals is to examine the relationship between biological processes and social media exposures, particularly with regards to elucidating suicide risk. First, we will test whether social neural network alterations increase susceptibility to negative social media exposures. Second, we will test whether negative social media exposures negatively impact HPA axis activity. Last, we will test whether negative social media exposures, social neural alterations, HPA axis activity, and their interactions lead to the emergence of suicide events (i.e., actual, interrupted, or aborted attempts; active suicidal ideation with method, intent, or plan; emergency department visits or psychiatric hospitalizations for STB). Through this comprehensive approach, we will address a critical public health initiative by identifying those who are susceptible to negative social media exposures, and providing actionable markers to reduce the needless loss of life among young people.

项目摘要 在过去的15年里，青少年的自杀率上升了60%。最近，有问题的 社交媒体的使用与自杀念头和行为（STB）的出现有关，这或许反映了 更大的人际压力暴露了解人际压力的类型、时间和严重程度 暴露对于了解STB风险至关重要，这需要仔细描述其 通过对社交媒体中实时互动的深入询问来改善数字生活。根据压力 一代框架，经历精神障碍的青少年具有增加的特征， 人际压力的发生，可能包括负面的社交媒体曝光。因此，这 该项目将确定可能增加负面社交媒体发生率的社交神经敏感性 暴露和检查生理过程受到负面社交媒体曝光的影响， 时间我们的研究将包括14-17岁的青少年（N=300），这将是高风险青少年的过采样 自杀（n=200），定义为过去3个月内的STB和/或过去一年的自杀企图。此外，我们将 招募患有精神疾病但没有STB终身史的青少年（n=100），提供 有机会识别生物标志物和时间上精确的社交媒体暴露，以表征风险 而不是更广泛地识别与精神疾病相关的风险因素。 将在基线时完成全面的临床评估，此外，我们将调查过去一年的情况。 用户生成的内容，以评估负面暴露的动态变化， （a）网上受害（例如，骚扰、仇恨言论），（B） 减少的社会资本（例如，减少的社交网络大小），以及（c）减少的社交支持（例如，减少 参与，消息传递的互惠性）。我们还将收集基线功能磁共振成像神经反应， 过程和评估慢性HPA轴活动。在2个月、4个月和6个月的随访评估、访谈中， 将重新评估社交媒体数据、HPA轴活动和自我报告。总体目标是检查 生物过程和社交媒体曝光之间的关系，特别是关于 说明自杀风险。首先，我们将测试社交神经网络的改变是否会增加对以下疾病的易感性 社交媒体负面曝光其次，我们将测试负面社交媒体曝光是否会产生负面影响， 影响HPA轴活动。最后，我们将测试是否负面的社交媒体曝光，社交神经改变， HPA轴活动，以及它们的相互作用导致自杀事件的出现（即，实际、中断或 流产企图;主动自杀意念与方法，意图或计划;急诊科就诊或精神科就诊 因STB住院）。通过这一全面的方法，我们将处理一项重要的公共卫生倡议， 通过识别那些容易受到负面社交媒体曝光的人，并提供可操作的标记， 减少年轻人不必要的生命损失。