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1/4 Powering Genetic Discovery for Severe Mental Illness in Latin American and African Ancestries

1/4 Powering Genetic Discovery for Severe Mental Illness in Latin American and African Ancestries
1/4 推动拉丁美洲和非洲血统中严重精神疾病的基因发现
批准号：
10818964
负责人：
Alicia Martin
金额：
$99.85万
依托单位：
BROAD INSTITUTE, INC.
依托单位国家：
美国
项目类别：
财政年份：
2020
资助国家：
美国
项目状态：
未结题
起止时间：
2020-09-14 至 2025-07-31
来源：
https://reporter.nih.gov/project-details/10818964
关键词：
AccelerationAdministrative SupplementAfricanAfrican ancestryAnhedoniaAsianAwarenessBipolar DisorderCognitionCommunitiesConsensusCountryDataData AnalysesData AnalyticsData CollectionDepositionDiagnosisDimensionsDiscriminationDiseaseEnvironmentEquityEthicsFutureGeneticGenetic ResearchGenetic studyGoalsHealthcare SystemsHeritabilityIndividualKenyaLatin AmericanMeasurementMeasuresMental HealthMental disordersMethodologyNational Institute of Mental HealthObsessive compulsive behaviorPhenotypePopulationPopulation HeterogeneityProceduresProcessPropertyPsychometricsReproducibilityResourcesSchizophreniaSiteStandardizationSymptomsTestingTraining ActivityUgandaUnderrepresented Populationscognitive functioncohortdata archivedisease phenotypeinnovationinstrumentmemberphenotypic datapsychogeneticssevere mental illnesssimulationskillssocial stigmasuicidaltraitworking group

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中文摘要
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英文摘要
PROJECT SUMMARY This project actualizes a primary goal of the Ancestral Populations Network (APN; PAR-20-026 and PAR-20- 027), namely to facilitate measurement and data analytic harmonization efforts across APN members to enhance rigor and reproducibility and generate a resource for network members and the scientific community. Through a consensus process of APN members, measures of anhedonia, cognition, obsessive-compulsive symptoms, suicidality, and discrimination/stigma were selected for harmonization across ongoing studies. These harmonized measures will be collected across an estimated 27,500 individuals representing Asian, Latin American, and African ancestries spanning over 15 countries.
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1/4 Powering Genetic Discovery for Severe Mental Illness in Latin American and African Ancestries
  • 批准号：
    10697312
  • 项目类别：
  • 资助金额：
    $287.98万
  • 财政年份：
    2020
  • 负责人：
    Alicia Martin
  • 依托单位：
    BROAD INSTITUTE, INC.
1/4 Powering Genetic Discovery for Severe Mental Illness in Latin American and African Ancestries
  • 批准号：
    10483138
  • 项目类别：
  • 资助金额：
    $166.47万
  • 财政年份：
    2020
  • 负责人：
    Alicia Martin
  • 依托单位：
    BROAD INSTITUTE, INC.
Generalizing polygenic risk prediction methods across populations for insights into psychiatric disease
  • 批准号：
    10252959
  • 项目类别：
  • 资助金额：
    $24.15万
  • 财政年份：
    2020
  • 负责人：
    Alicia Martin
  • 依托单位：
    MASSACHUSETTS GENERAL HOSPITAL
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