Towards Cervical cancer elimination: Implementation and scale-up of a single-visit, screen-and-treat approach with thermal ablation for sustainable cervical cancer prevention services in Kenya

消除宫颈癌:在肯尼亚实施和扩大单次就诊、筛查和治疗的热消融方法,以提供可持续的宫颈癌预防服务

基本信息

  • 批准号:
    10843625
  • 负责人:
  • 金额:
    $ 12.45万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2021
  • 资助国家:
    美国
  • 起止时间:
    2021-09-21 至 2026-08-31
  • 项目状态:
    未结题

项目摘要

ABSTRACT This application is submitted in response to the Notice of Special Interest (NOSI) identified as NOT-CA-23- 038 “Administrative Supplements for NCI Global Oncology Mentored Research” and proposes an administrative supplement to our parent award R01CA258590. Background While prevention and treatment strategies exist for cervical cancer, it remains the leading cause of mortality in Sub-Saharan Africa. The timely screening, early diagnosis and treatment of precancerous cervical lesions is key in reducing the disease burden. Current treatment goals have focused on ablative methods but there are women who require different treatment either by excision, hysterectomy, or radiotherapy. We will conduct a mixed methods study on Kenyan women with precancerous cervical lesions who are not amendable to ablative therapy and referred by our study for other treatment- little research is available for this group. Women will be recruited from the parent grant TIBA clinics. We will evaluate this via the following two aims: AIM 1: Evaluate the barriers and facilitators (health system, health care provider and client levels) in the referral and linkage to care for women who screen positive for pre-cancerous lesions and not amenable to ablative therapy. We shall conduct semi-structured surveys, focused group discussions and in-depth interviews to gain information on the barriers and facilitators from the health care providers and clients. AIM 2a: Determine the proportion of women with pre-cancerous cervical lesions and not amenable to ablation therapy who access treatment within a four-month period. All women who are screen-positive and not eligible for ablative therapy will be invited to participate in this study and followed up for a period of four months to determine whether they are treated or not. AIM 2b: Conduct flow mapping of existing referral services for women who screen positive for pre-cancer lesions and not amenable for ablative therapy with a focus on identifying the steps that create barriers to treatment access. A sample of four to five women who screen positive for pre-cancer lesions but who are not amenable to thermal ablation and health care providers will be interviewed to perform flow mapping. Barriers and facilitators to treatment access will be catalogued during the flow mapping process The objective of this study is to understand the bottlenecks in the cervical cancer care continuum following referral and linkage of these women. This will form the basis of future studies that will enhance seamless integration for women with precancerous cervical lesions referred for treatment.
摘要

项目成果

期刊论文数量(1)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Implementation and scale-up of a single-visit, screen-and-treat approach with thermal ablation for sustainable cervical cancer prevention services: a protocol for a stepped-wedge cluster randomized trial in Kenya.
  • DOI:
    10.1186/s13012-023-01282-3
  • 发表时间:
    2023-06-26
  • 期刊:
  • 影响因子:
    7.2
  • 作者:
    Shin, Michelle B.;Oluoch, Lynda Myra;Barnabas, Ruanne V.;Baynes, Colin;Fridah, Harriet;Heitner, Jesse;Kerubo, Mary Bernadette;Ngure, Kenneth;Pinder, Leeya F.;Thomas, Katherine K.;Mugo, Nelly Rwamba;Gimbel, Sarah
  • 通讯作者:
    Gimbel, Sarah
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Sarah Odell Gimbel其他文献

Sarah Odell Gimbel的其他文献

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{{ truncateString('Sarah Odell Gimbel', 18)}}的其他基金

Systems analysis and improvement to optimize opioid use disorder care quality and continuity for patients exiting jail (SAIA-MOUD).
系统分析和改进,以优化出狱患者的阿片类药物使用障碍护理质量和连续性 (SAIA-MOUD)。
  • 批准号:
    10832930
  • 财政年份:
    2023
  • 资助金额:
    $ 12.45万
  • 项目类别:
Towards Cervical cancer elimination: Implementation and scale-up of a single-visit, screen-and-treat approach with thermal ablation for sustainable cervical cancer prevention services in Kenya
消除宫颈癌:在肯尼亚实施和扩大单次就诊、筛查和治疗的热消融方法,以提供可持续的宫颈癌预防服务
  • 批准号:
    10180713
  • 财政年份:
    2021
  • 资助金额:
    $ 12.45万
  • 项目类别:
Towards Cervical cancer elimination: Implementation and scale-up of a single-visit, screen-and-treat approach with thermal ablation for sustainable cervical cancer prevention services in Kenya
消除宫颈癌:在肯尼亚实施和扩大单次就诊、筛查和治疗的热消融方法,以提供可持续的宫颈癌预防服务
  • 批准号:
    10491699
  • 财政年份:
    2021
  • 资助金额:
    $ 12.45万
  • 项目类别:
Towards Cervical cancer elimination: Implementation and scale-up of a single-visit, screen-and-treat approach with thermal ablation for sustainable cervical cancer prevention services in Kenya
消除宫颈癌:在肯尼亚实施和扩大单次就诊、筛查和治疗的热消融方法,以提供可持续的宫颈癌预防服务
  • 批准号:
    10693340
  • 财政年份:
    2021
  • 资助金额:
    $ 12.45万
  • 项目类别:
Systems Analysis and Improvement Approach to Optimize the Hypertension Diagnosis and Care Cascade for HIV-infected Individuals (SAIA-HTN)
优化 HIV 感染者高血压诊断和护理级联的系统分析和改进方法 (SAIA-HTN)
  • 批准号:
    10392907
  • 财政年份:
    2019
  • 资助金额:
    $ 12.45万
  • 项目类别:
Systems Analysis and Improvement Approach to Optimize the Hypertension Diagnosis and Care Cascade for HIV-infected Individuals (SAIA-HTN)
优化 HIV 感染者高血压诊断和护理级联的系统分析和改进方法 (SAIA-HTN)
  • 批准号:
    10617293
  • 财政年份:
    2019
  • 资助金额:
    $ 12.45万
  • 项目类别:
Systems Analysis and Improvement Approach to Optimize the Hypertension Diagnosis and Care Cascade for HIV-infected Individuals (SAIA-HTN)
优化 HIV 感染者高血压诊断和护理级联的系统分析和改进方法 (SAIA-HTN)
  • 批准号:
    10153876
  • 财政年份:
    2019
  • 资助金额:
    $ 12.45万
  • 项目类别:
Systems Analysis and Improvement Approach to Optimize the Hypertension Diagnosis and Care Cascade for HIV-infected Individuals (SAIA-HTN)
优化 HIV 感染者高血压诊断和护理级联的系统分析和改进方法 (SAIA-HTN)
  • 批准号:
    9924633
  • 财政年份:
    2019
  • 资助金额:
    $ 12.45万
  • 项目类别:
Usability and Feasibility of a Phone-based Decision Support Tool for Option B+
选项 B 的基于电话的决策支持工具的可用性和可行性
  • 批准号:
    9116602
  • 财政年份:
    2016
  • 资助金额:
    $ 12.45万
  • 项目类别:

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