The Role of Perturbed Auditory Information for Self-motion in Gait

扰动听觉信息对步态中自我运动的作用

• 批准号: 10891772
• 负责人: Dobromir Dotov
• 金额: $ 16.15万
• 依托单位: UNIVERSITY OF NEBRASKA OMAHA
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-08-01 至 2024-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10891772
• 关键词: Activities of Daily Living; Address; Adult; Area; Attention; Auditory; Auditory system; Brain imaging; Cognitive; Control Groups; Coupling; Disease; Elderly; Electroencephalography; Event; Exhibits; Feedback; Gait; Individual; Measures; Motion; Motor; Movement; Participant; Persons; Phase; Role; Sensory; Stimulus; System; Testing; Time; Training; Visit; Walking; Work; cognitive system; falls; functional near infrared spectroscopy; gait rehabilitation; hearing impairment; improved; instrument; prevent; response; sound; success; treadmill; virtual reality; young adult

When people interact with objects such as opening a door, their movements make sounds that are associated with the success of the action. Similarly, when people walk their footsteps make sounds that are audible. It is possible that these sounds are used as feedback to stabilize and adapt movement. There is some evidence for such a connection between the auditory and motor systems in activities of daily living, yet the empirical work is insufficient and indirect. The objective of the project is to address this gap by investigating the functional connection between gait dynamics and stepping sounds. In each of the three proposed studies, the delay and amplitude of self-produced footstep sounds will be manipulated while young healthy adults are performing a self-paced treadmill walking task. To this end, a gait real-time analysis interactive lab will be programmed. The apparatus consists of an instrumented treadmill and virtual reality sound projection capability. The overall hypothesis is that walking cadence will change proportionally to the magnitude and sign of the manipulation of footstep sounds. Furthermore, the statistical persistence of inter-step intervals will decrease as a function of feedback alteration. Next to these motor responses, the proposed project will investigate associated cortical responses by using mobile brain imaging. One study will use fNIRS to focus on measures associated with attentional demand. A second study will use a combination of mobile EEG and EMG to investigate cortico-spinal synchronization. The third study will evaluate whether repetitive sessions of so-called stealth walking hold potential for improving gait dynamics and variability. The study will involve five visits to the lab. Participants’ task will be to step so as to minimize the otherwise augmented feedback from the their footstep sounds. Change in gait parameters from pre- to post-training will be compared to a control group.

当人们与物体互动时，比如开门，他们的动作会发出声音， 与行动的成功有关。同样，当人们走路时，他们的脚步声会发出声音， 是可以听到的这些声音可能被用作反馈以稳定和适应运动。那里 是一些证据，证明在日常活动中听觉和运动系统之间存在这种联系。 生活，但经验的工作是不够的和间接的。该项目的目标是弥补这一差距 通过研究步态动力学和脚步声之间的功能联系。的每一个中 三个拟议的研究，延迟和幅度的自产脚步声将被操纵 而年轻健康的成年人正在执行自定步调的跑步机行走任务。为此，步态实时 分析互动实验室将被编程。该装置包括一个装有仪表的跑步机， 虚拟现实声音投影能力。总的假设是，步行节奏将改变 与脚步声操纵的幅度和符号成比例。而且 步间间隔的统计持续性将作为反馈改变的函数而降低。旁边 这些运动反应，拟议的项目将调查相关的皮质反应，通过使用 移动的脑成像。一项研究将使用fNIRS来关注与注意力需求相关的措施。 第二项研究将使用移动的EEG和EMG的组合来研究皮质脊髓 同步第三项研究将评估重复的所谓隐形行走是否能保持 改善步态动力学和可变性的潜力。该研究将涉及五次实验室访视。 参与者的任务将是逐步减少来自他们的反馈， 脚步声。将步态参数从训练前到训练后的变化与对照组进行比较。