CVD KNOWLEDGE/MORBIDITY--SOCIOECONOMIC COHORT OUTCOMES

CVD 知识/发病率——社会经济队列结果

• 批准号: 2876594
• 负责人: Sharon K Davis
• 金额: $ 3.44万
• 依托单位: HARVARD MEDICAL SCHOOL
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-03-15 至 1999-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2876594
• 关键词: behavioral /social science research tag; cardiovascular disorder epidemiology; clinical research; disease /disorder proneness /risk; health behavior; health education; human data; human morbidity; prognosis; socioeconomics

Evidence shows a growing disparity in the prevalence of modifiable risk factors and incidence of cardiovascular disease (C.D.) between upper and lower socioeconomic status (SES) individuals. Trends in knowledge about risk factors and risk reduction strategies parallel these findings. Research determining the differential association between level of C.D. knowledge and subsequent clinical health status has not been conducted. The purpose of this research is to elucidate the interrelationship by merging population-based, C.D. risk factor survey data with patient-level hospital data. The overall goal is to assess outcomes in the +/- association between level of C.D. knowledge and incidence and relative degree of morbidity among a cohort with and without major C.D. risk factors. The study population will be comprised of 2,560 adults, aged 21- 74 years, who took part in the final Stanford five-City (FCP cross- sectional survey in 1989/90. Analyses will be stratified according to SES (via years of formal education), controlling for age, gender, and ethnicity (Latino/Anglo). Sociodemographic, physiologic, and knowledge measurements are available on each participant. Morbidity estimates and clinical health status indicators are available via primary and secondary discharge diagnostic codes from public-use hospital discharge databases collected on all California hospital admissions for the entire study period. The FCP data will be merged with the hospital discharge data, matching on survey participant~s social security number which will be subsequently converted to a unique personal identifier. Baseline 1989/90 and 1991 through 1995 longitudinal outcomes will be assessed. There are three main aims, all of which have epidemiologic and C.D. health policy prevention implications: Aim 1: Characterize the distribution of hospitalized versus non- hospitalized SES sub-cohorts according to level of C.D. knowledge, physiologic risk factor prevalence, and clinical morbidity prevalence. Aim 2: Test the hypothesis that morbidity differences between hospitalized SES sub-cohorts will vary as a function of baseline level of C.D. knowledge and risk factor prevalence. Aim 3: Test the hypothesis that morbidity will rise among hospitalized lower SES sub-cohorts, resulting in widening health status disparities by the end of the study period. Parametric and nonparametric analytic methods will be used, including analysis of variance and covariance, and various regression techniques.

有证据表明，可改变风险的流行率差距越来越大 上层和下层之间心血管疾病（C.D.）的影响因素和发病率 社会经济地位 (SES) 较低的个体。 有关知识的趋势 风险因素和风险降低策略与这些发现相似。 研究确定 C.D. 水平之间的差异关联。 尚未进行了解和随后的临床健康状况。 本研究的目的是通过以下方式阐明其相互关系： 基于人口的合并，C.D.患者层面的危险因素调查数据 医院数据。 总体目标是评估 +/- 内的结果 C.D.水平之间的关联知识、发生率和相关性 患有和不患有严重CD的队列中的发病程度风险 因素。 研究人群将包括 2,560 名成年人，年龄在 21 岁至 74年，谁参加了斯坦福五城（FCP跨界）决赛 1989/90 年度的分段调查。 分析将根据 SES 进行分层 （通过多年的正规教育），控制年龄、性别和 种族（拉丁裔/盎格鲁裔）。 社会人口学、生理学和知识 每个参与者都可以进行测量。 发病率估计和 临床健康状况指标可通过初级和次级获得 来自公共医院出院数据库的出院诊断代码 收集了整个研究期间所有加州住院患者的数据 时期。 FCP 数据将与出院数据合并， 匹配调查参与者的社会安全号码，这将是 随后转换为唯一的个人标识符。 1989/90 基线 并将评估 1991 年至 1995 年的纵向结果。 有 三个主要目标，所有这些目标都具有流行病学和 C.D.卫生政策 预防影响： 目标 1：描述住院患者与非住院患者的分布特征 根据 C.D. 级别住院 SES 分组知识， 生理危险因素的患病率和临床发病率。 目标 2：检验住院患者之间发病率差异的假设 SES 子队列将根据 C.D. 基线水平而变化。 知识和危险因素的流行情况。 目标 3：检验住院患者发病率将会上升的假设 社会经济地位较低的子群体，导致健康状况差距扩大 学习期结束。 将使用参数和非参数分析方法，包括 方差和协方差分析以及各种回归技术。