CVD KNOWLEDGE/MORBIDITY--SOCIOECONOMIC COHORT OUTCOMES

CVD 知识/发病率——社会经济队列结果

• 批准号: 6293649
• 负责人: Sharon K Davis
• 金额: $ 4.02万
• 依托单位: MOREHOUSE SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-03-15 至 2001-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6293649
• 关键词: behavioral /social science research tag; cardiovascular disorder epidemiology; clinical research; disease /disorder proneness /risk; health behavior; health education; human data; human morbidity; prognosis; socioeconomics

Evidence shows a growing disparity in the prevalence of modifiable risk factors and incidence of cardiovascular disease (C.D.) between upper and lower socioeconomic status (SES) individuals. Trends in knowledge about risk factors and risk reduction strategies parallel these findings. Research determining the differential association between level of C.D. knowledge and subsequent clinical health status has not been conducted. The purpose of this research is to elucidate the interrelationship by merging population-based, C.D. risk factor survey data with patient-level hospital data. The overall goal is to assess outcomes in the +/- association between level of C.D. knowledge and incidence and relative degree of morbidity among a cohort with and without major C.D. risk factors. The study population will be comprised of 2,560 adults, aged 21- 74 years, who took part in the final Stanford five-City (FCP cross- sectional survey in 1989/90. Analyses will be stratified according to SES (via years of formal education), controlling for age, gender, and ethnicity (Latino/Anglo). Sociodemographic, physiologic, and knowledge measurements are available on each participant. Morbidity estimates and clinical health status indicators are available via primary and secondary discharge diagnostic codes from public-use hospital discharge databases collected on all California hospital admissions for the entire study period. The FCP data will be merged with the hospital discharge data, matching on survey participant~s social security number which will be subsequently converted to a unique personal identifier. Baseline 1989/90 and 1991 through 1995 longitudinal outcomes will be assessed. There are three main aims, all of which have epidemiologic and C.D. health policy prevention implications: Aim 1: Characterize the distribution of hospitalized versus non- hospitalized SES sub-cohorts according to level of C.D. knowledge, physiologic risk factor prevalence, and clinical morbidity prevalence. Aim 2: Test the hypothesis that morbidity differences between hospitalized SES sub-cohorts will vary as a function of baseline level of C.D. knowledge and risk factor prevalence. Aim 3: Test the hypothesis that morbidity will rise among hospitalized lower SES sub-cohorts, resulting in widening health status disparities by the end of the study period. Parametric and nonparametric analytic methods will be used, including analysis of variance and covariance, and various regression techniques.

有证据表明，在可改变的风险的流行程度方面， 因素和心血管疾病发病率（C.D.）的上 社会经济地位（SES）较低的人。 知识趋势 风险因素和减少风险战略与这些调查结果相似。 确定慢性阻塞性肺疾病（C.D.） 知识和随后的临床健康状况尚未进行。 本研究的目的是阐明相互关系， 合并人口为基础，C.D.患者水平的危险因素调查数据 医院数据 总体目标是评估+/- C.D.水平之间的关联知识与关联 有和无严重C.D.的队列中的发病率程度风险 因素 研究人群将由2，560名21岁至21岁的成年人组成 74年，谁参加了最后的斯坦福大学五城（FCP跨- 1989/1990年进行了分区调查。 分析将根据SES分层 (via年的正规教育），控制年龄，性别， 种族（拉丁美洲人/盎格鲁人）。 社会人口、生理和知识 每个参与者都有测量数据。 Moreover估计， 通过初级和次级提供临床健康状态指标 公共医院出院数据库中的出院诊断代码 收集整个研究期间所有加州医院的入院数据 期 FCP数据将与出院数据合并， 匹配调查参与者的社会安全号码， 随后转换为唯一的个人标识符。 1989/90年基线 并将评估1991年至1995年的纵向结果。 有 三个主要目标，所有这些都有流行病学和C. D.卫生政策 预防影响： 目的1：描述住院与非住院患者的分布特征 根据C.D.水平的住院SES亚队列知识， 生理危险因素患病率和临床发病率。 目的2：检验住院患者之间的发病率差异 SES子队列将根据基线C.D.水平而变化。 知识和危险因素流行率。 目的3：检验住院患者的发病率将上升的假设 社会经济地位较低的子队列，导致健康状况差距扩大， 研究期结束时。 将使用参数和非参数分析方法，包括 方差和协方差分析，以及各种回归技术。