Cardiovascular Disease Preventive Intervention Program

心血管疾病预防干预计划

• 批准号: 7792490
• 负责人: Sharon K Davis
• 金额: $ 69.58万
• 依托单位: MOREHOUSE SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-05-15 至 2012-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7792490
• 关键词: Address; African American; Alabama; American; Area; Arts; Award; Basic Science; Behavioral; Biochemical; Biology; Biomedical Research; Biometry; Blood Vessels; Cardiovascular Diseases; Cardiovascular system; Centers for Disease Control and Prevention (U.S.); Centers of Research Excellence; Clinical Research; Clinical Sciences; Clinical Trials; Collaborations; Commit; Communities; Community Health; Complement; Development; Disease; Doctor of Philosophy; Education; Elements; Ensure; Environment; Epidemiologist; Epidemiology; Evaluation; Faculty; Fostering; Future; Gender; Genomics; Geographic Locations; Goals; Grant; Growth; Health; Hylobates Genus; Institutes; Institution; Intervention Studies; Knowledge; Leadership; Location; Master of Public Health; Medical; Medical Students; Mentors; Minority; Molecular; Molecular Genetics; Nature; Neurosciences; Phase; Physiological; Pilot Projects; Play; Population; Population Sciences; Positioning Attribute; Postdoctoral Fellow; Prevention Research; Preventive Intervention; Preventive Medicine; Primary Care Physician; Primary Health Care; Principal Investigator; Process; Productivity; Public Health; Public Health Practice; Qualifying; Recruitment Activity; Research; Research Activity; Research Institute; Research Personnel; Research Training; Resolution; Resources; Role; Science; Scientist; Series; Shapes; Source; South Carolina; Strategic Planning; Structure; Students; Surgeon; Technology; Training Programs; U-Series Cooperative Agreements; United States; United States National Institutes of Health; Universities; Vision; base; expectation; experience; genetic epidemiology; graduate student; health disparity; innovation; intervention program; medical schools; member; next generation; novel; organizational structure; population based; prevent; programs; research and development; role model; success; working group

DESCRIPTION (provided by applicant): It is postulated that the resolution of the problem of ethnic disparities in the burden of cardiovascular diseases will require a concerted, multi-disciplinary approach that includes investigators and practitioners dedicated to serving ethnic populations within their communities. This proposal seeks to establish a community-oriented Cardiovascular Disease Preventive Intervention Research Program (CPIP) at the Morehouse School of Medicine (MSM). This program is an essential step towards establishing a comprehensive research center of excellence in cardiovascular science that achieves the inter-disciplinary integration of basic science, clinical investigation and population-based research that is necessary to redress the problem of ethnic disparities in cardiovascular health. The long-term scientific objectives of the proposed program are two-fold: 1) to discover the etiologic basis for ethnic and geographic disparities in cardiovascular disease in the United States and 2) to pursue research that generates innovative, community-based preventive intervention programs that will reduce or eliminate these disparities. A complementary educational objective of the CPIP is to nurture the development of the next generation of cardiovascular investigators with a particular emphasis on expanding the ethnic and gender diversity of the research community. The primary objective of Phase I is to recruit a Program Director of the CPIP with a track record of scientific excellence in population-based cardiovascular science. The specific aims of Phase I are: To establish the administrative and search committee structure necessary to implement an effective recruitment plan for the CPIP Program Director. To establish an External Advisory Board composed of scientific leaders in cardiovascular research that will provide consultative input on the programmatic development of the CPIP and identification of the CPIP Program Director. To enhance a novel integrative approach to cardiovascular disease-related research by facilitating institution-wide, multi-disciplinary research collaborations within the MSM community as well as our regional partners.

描述（由申请人提供）： 据推测，解决心血管疾病负担中的种族差异问题将需要协调一致的多学科方法，其中包括致力于为社区内少数民族人口服务的调查人员和从业人员。 该提案旨在在莫尔豪斯医学院（MSM）建立一个面向社区的心血管疾病预防干预研究项目（CPIP）。 该计划是建立心血管科学卓越的综合研究中心的重要一步，实现了基础科学，临床研究和基于人群的研究的跨学科整合，这是解决心血管健康种族差异问题所必需的。 该计划的长期科学目标有两个方面：1）发现美国心血管疾病种族和地理差异的病因学基础; 2）进行研究，产生创新的，以社区为基础的预防干预计划，减少或消除这些差异。 CPIP的一个补充教育目标是培养下一代心血管研究者的发展，特别强调扩大研究界的种族和性别多样性。 第一阶段的主要目标是招募一名CPIP的项目主任，该项目主任在基于人群的心血管科学方面具有卓越的科学记录。 第一阶段的具体目标是： 建立必要的行政和招聘委员会结构，以实施CPIP项目总监的有效招聘计划。 建立一个由心血管研究领域的科学领导人组成的外部咨询委员会，为CPIP的项目开发和CPIP项目负责人的确定提供咨询意见。 通过促进MSM社区以及我们的区域合作伙伴内的机构范围内的多学科研究合作，增强心血管疾病相关研究的新综合方法。

项目成果

Associations of adiponectin and leptin with incident coronary heart disease and ischemic stroke in african americans: the jackson heart study.

• DOI: 10.3389/fpubh.2013.00016
• 发表时间: 2013
• 期刊: Frontiers in public health
• 影响因子: 5.2
• 作者: Bidulescu A;Liu J;Chen Z;Hickson DA;Musani SK;Samdarshi TE;Fox ER;Taylor HA;Gibbons GH
• 通讯作者: Gibbons GH

Circadian CLOCK gene polymorphisms in relation to sleep patterns and obesity in African Americans: findings from the Jackson heart study.

• DOI: 10.1186/s12863-017-0522-6
• 发表时间: 2017-06-23
• 期刊: BMC genetics
• 影响因子: 2.9
• 作者: Riestra P;Gebreab SY;Xu R;Khan RJ;Gaye A;Correa A;Min N;Sims M;Davis SK
• 通讯作者: Davis SK

Association of adiponectin with type 2 diabetes and hypertension in African American men and women: the Jackson Heart Study.

非裔美国人男女的脂联素与2型糖尿病和高血压的关联：杰克逊心脏研究。

• DOI: 10.1186/s12872-015-0005-5
• 发表时间: 2015-02-25
• 期刊: BMC cardiovascular disorders
• 影响因子: 2.1
• 作者: Davis SK;Gebreab SY;Xu R;Riestra P;Khan RJ;Sumner AE;Hickson D;Bidulescu A
• 通讯作者: Bidulescu A

Gender-specific associations between ADIPOQ gene polymorphisms and adiponectin levels and obesity in the Jackson Heart Study cohort.

• DOI: 10.1186/s12881-015-0214-x
• 发表时间: 2015-08-20
• 期刊: BMC medical genetics
• 作者: Riestra P;Gebreab SY;Xu R;Khan RJ;Bidulescu A;Correa A;Tekola-Ayele F;Davis SK
• 通讯作者: Davis SK

Associations of adiponectin with individual European ancestry in African Americans: the Jackson Heart Study.

• DOI: 10.3389/fgene.2014.00022
• 发表时间: 2014
• 期刊: Frontiers in genetics
• 影响因子: 3.7
• 作者: Bidulescu A;Choudhry S;Musani SK;Buxbaum SG;Liu J;Rotimi CN;Wilson JG;Taylor HA;Gibbons GH
• 通讯作者: Gibbons GH