课题基金 / 基金详情

SELECTIVE AUTOPHAGIC DEGRADATION OF PEROXISOMES IN YEAST

SELECTIVE AUTOPHAGIC DEGRADATION OF PEROXISOMES IN YEAST
酵母中过氧化物酶体的选择性自噬降解
批准号：
2546693
负责人：
James Michael Cregg
金额：
$2.0万
依托单位：
OREGON HEALTH & SCIENCE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
1995
资助国家：
美国
项目状态：
已结题
起止时间：
1995-09-30 至 1998-09-29
来源：
https://reporter.nih.gov/project-details/2546693
关键词：
cooperative study electron microscopy gene complementation genetic library lysosomes molecular cloning mutant peroxisome protein sequence vesicle /vacuole yeasts

项目摘要

项目成果

James Michael Cregg的其他基金

相似基金

相关文献

中文摘要
翻译
点击翻译按钮获取中文摘要
英文摘要
DESCRIPTION: The proposed research involves investigating the molecular mechanisms which control the selective degradation of peroxisomes in Pichia pastoris. It is proposed to isolate mutants that are defective in the degradation of methanol degrading peroxisomes and to characterize these biochemically and cytologically. The peroxisome degrading genes will be isolated by functional complementation, sequenced and the amino acid sequence deduced. Mutant and wild type sequences will be compared to provide insight concerning function. The second aim of the proposed research is to isolate peroxisome biogenesis defective mutants via the development of new approaches for positive selection. The physiological characteristics of these mutants will be studied.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Improved Tools for Expression of Recombinant Genes in the Yeast Pichia pastoris
  • 批准号：
    8325621
  • 项目类别：
  • 资助金额：
    $20.0万
  • 财政年份：
    2011
  • 负责人：
    James Michael Cregg
  • 依托单位：
    BIOGRAMMATICS, INC.
Improved Tools for Expression of Recombinant Genes in the Yeast Pichia pastoris
  • 批准号：
    8126091
  • 项目类别：
  • 资助金额：
    $20.0万
  • 财政年份：
    2011
  • 负责人：
    James Michael Cregg
  • 依托单位：
    BIOGRAMMATICS, INC.
Novel peroxisomal genes in the yeast Pichia pastoris
Novel peroxisomal genes in the yeast Pichia pastoris
海外基金