SCHEDULED, GRADUAL REDUCTION FOR SMOKING CESSATION

有计划、逐步减少戒烟

• 批准号: 2114904
• 负责人: ALBERT JEROME
• 金额: $ 9.98万
• 依托单位: PERSONAL IMPROVEMENT COMPUTER SYSTEMS
• 依托单位国家: 美国
• 财政年份: 1996
• 资助国家: 美国
• 起止时间: 1996-09-01 至 1998-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2114904
• 关键词: biomaterial development /preparation; clinical research; computer assisted instruction; computer program /software; human subject; questionnaires; self help; smoking cessation; statistics /biometry

DESCRIPTION: The overall goal of this project is to develop a second generation computerized self-help intervention for smoking cessation. The program, LifeSign-II, will incorporate significant enhancements to the current commercial program, LifeSign-I, that will result in a product that is simpler to use and more effective. The LifeSign program utilizes a credit-card sized hand-held computer to implement a scheduled, gradual reduction protocol to extinguish smoking. Modifications that will be developed and tested include: 1) providing a mechanism to adjust the pace of the withdrawal program according to input provided by users, and 2) making the program more sensitive to baseline smoking rates by dividing the baseline period into discrete segments. Withdrawal curves will then be implemented separately within each segment. This Phase I project will include development of a first generation prototype system and a 10-week feasibility study with 100 smokers. Smokers will be randomly assigned to one of two conditions: LifeSign-I or LifeSign-II. Criteria for feasibility will be statistically significant differences between groups on compliance with withdrawal program; degree of withdrawal symptoms and urges to smoke; and ratings of program speed. During Phase II, a second generation prototype will be developed and evaluated in a large-scale clinical trial.

描述：该项目的总体目标是开发第二代计算机自助戒烟干预。 该计划，生命体征-二，将纳入显着增强目前的商业计划，生命体征-一，这将导致一个产品，更简单的使用和更有效。 LifeSign计划利用一个信用卡大小的手持计算机来执行一个计划的、逐渐减少的方案来戒烟。 将开发和测试的修改包括：1）提供一种机制，根据用户提供的输入调整戒断计划的速度，2）通过将基线期划分为离散段，使计划对基线吸烟率更加敏感。 然后，将在每个部分中单独实施戒断曲线。 第一阶段项目将包括开发第一代原型系统和对100名吸烟者进行为期10周的可行性研究。 吸烟者将被随机分配到两个条件之一：生命体征-I或生命体征-II。 可行性标准将是组间在戒断方案依从性、戒断症状和吸烟冲动程度以及方案速度评级方面的统计学显著差异。 在第二阶段，将开发第二代原型，并在大规模临床试验中进行评估。