Mechanisms for the extinction of drug-seeking

消除毒品寻求的机制

• 批准号: nhmrc : 630406
• 负责人: Prof Gavan Mcnally
• 金额: $ 33.92万
• 依托单位: The University of New South Wales
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2010
• 资助国家: 澳大利亚
• 起止时间: 2010-01-01 至 2013-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/mechanisms-extinction-drug-seeking/78434
• 关键词: Mechanisms; extinction; drug; seeking

Drug addiction imposes significant burdens on individual drug users, their families, and communities. This project uses an animal model to identify the brain regions and pathways which mediate extinction of drug seeking and therefore contribute to long-term abstinence from drug-seeking. The work will show how the brain inhibits drug-seeking and will contribute to the important goal of identifying new approaches to preventing relapse to drug-seeking.

吸毒成瘾给吸毒者个人、他们的家庭和社区带来了沉重的负担。该项目使用动物模型来确定介导药物寻求消失的大脑区域和途径，从而有助于长期戒断药物寻求。这项工作将展示大脑如何抑制药物寻求，并将有助于确定预防药物寻求复发的新方法的重要目标。