Mechanisms guiding pathfinding and positioning of cortical interneurons

指导皮质中间神经元寻路和定位的机制

• 批准号: nhmrc : 628517
• 负责人: A/Pr Julian Heng
• 金额: $ 41.45万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2010
• 资助国家: 澳大利亚
• 起止时间: 2010-01-01 至 2012-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/mechanisms-guiding-pathfinding-cortical-interneurons/98189
• 关键词: Mechanisms; guiding; pathfinding; positioning; cortical

Brain disorders place an economic and social burden on Australia and the personal costs of these illnesses are immeasurable. Several brain abnormalities are caused from the failure of neurons to position themselves in the correct location when the brain develops. Our study aims to discover how neurons move and what factors influence this process. It provides an understanding of normal brain development, as well as providing insight into what may go wrong in the formation of brain diseases.

脑部疾病给澳大利亚带来了经济和社会负担，这些疾病的个人成本是不可估量的。一些大脑异常是由神经元在大脑发育时无法将自己定位在正确的位置引起的。我们的研究旨在发现神经元如何运动以及哪些因素影响这一过程。它提供了对正常大脑发育的理解，并提供了对大脑疾病形成过程中可能出现的问题的见解。