Mechanisms of intestinal and systemic iron homeostasis in early infancy

婴儿早期肠道和全身铁稳态的机制

• 批准号: nhmrc : 1069854
• 负责人: Dr David Frazer
• 金额: $ 32.4万
• 依托单位: Queensland Institute of Medical Research
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2014
• 资助国家: 澳大利亚
• 起止时间: 2014-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/mechanisms-intestinal-systemic-early-infancy/455413
• 关键词: Mechanisms; intestinal; systemic; iron; homeostasis

Iron is essential trace element for normal health. Iron requirements are particularly high during early postnatal life to meet the needs of the growing infant. To accommodate these needs, intestinal iron absorption is extremely high at this time. We have previously shown that the iron absorption mechanism during suckling differs from that in adults and this project explores that mechanism in more detail. These studies have important implications for infant nutrition and dietary supplementation.

铁是正常健康所必需的微量元素。在出生后早期，铁的需求量特别高，以满足成长中的婴儿的需要。为了适应这些需要，此时肠道铁的吸收率极高。我们之前已经证明，哺乳过程中的铁吸收机制与成人不同，本项目更详细地探索了这一机制。这些研究对婴儿营养和膳食补充有重要意义。