2003 Gordon Research Conference - Biology of Aging

描述（由申请人提供）：资金要求提供部分支持的生物学老化戈登研究会议（GRC）;“老化：进化到干预”将在克拉里昂文图拉海滩酒店，文图拉，加利福尼亚州，2003年3月9日至14日举行。会议将由当选的共同主席John Tower博士、Eugenia Wang博士和Rudy Tanzi博士组织。本次会议的总体目标是汇集分子生物学，遗传学和生理学领域的领先老年学家，以促进对衰老机制的协同讨论和交流。在实验老年学的几个关键领域安排了最先进的会议。会议主题包括：衰老的进化，胰岛素样信号和寿命，线粒体和氧化应激，衰老疾病和健康，干细胞和组织修复，基因组不稳定性和衰老，衰老的激素控制。每一次会议的目的是将模型系统与人类健康研究相结合。这次会议的标题，“老龄化：演变到干预”是指通过每次会议达到两个主题。第一个是从进化的角度研究衰老。我们对寿命作为一种进化的生命史特征的理解已经取得了重大进展，这种理解指导并指导了对衰老的遗传学、分子生物学和生理学的分析。其次，该领域作为一个整体正在迅速发展，从一个主要的相关研究，以一个专注于实验和医疗干预到衰老过程。 请求提供资金，用于偿还约46名发言者和会议共同主席的会议费和差旅费。此外，还要求提供资金，以支持大约10名研究生、博士后研究员和新的初级教师的费用，他们将受益于会议并为会议做出贡献。戈登研究会议组织也提供了大量资金，并正在向私人基金会和工业界寻求更多资金。

DESCRIPTION (provided by applicant): Funds are requested to provide partial support for the Biology of Aging Gordon Research Conference (GRC) ;"Aging: Evolution to Intervention" to be held at Clarion Ventura Beach Hotel, Ventura, CA, Mar 9-14, 2003. The conference will be organized by the elected Co-Chairs Drs. John Tower, Eugenia Wang, and Rudy Tanzi. The overall aim of this conference is to bring together leading gerontologists in the fields of molecular biology, genetics and physiology to promote a synergistic discourse and exchange on the mechanisms of aging. State-of-the-art sessions are scheduled in several of the critical areas of experimental gerontology. Session topics include: Evolution of aging, Insulin-like signaling and life span, Mitochondria and oxidative stress, Aging diseases and healthspan, Stem cells and tissue repair, Genomic instability and aging, and Hormonal control of aging. Each session is designed to integrate model systems with studies of human health. The title of this meeting, "Aging: Evolution to Intervention" refers to two themes that reach through each session. The first is the study of aging from an evolutionary standpoint. Significant advances have been made in our understanding of life span as an evolved life history trait and this understanding has guided and informed analysis of the genetics, molecular biology and physiology of aging. Second, the field as a whole is rapidly evolving from one of primarily correlative studies to one focused on experimental and medical interventions into the aging process. Funds are requested to provide reimbursement for the conference fees and travel expenses of approximately 46 speakers plus the Conference Co-Chairs. In addition, funds are requested to support the expenses of approximately 10 graduate students, postdoctoral fellows, and new, junior faculty who would benefit from and contribute to the conference. Significant funding is also provided by the Gordon Research Conference Organization, and additional funds are being solicited from private foundations and industry.