HD2A RASC-Research and Evaluation Core

研究和评价核心：项目概要/摘要 虽然有效的初级预防、减少伤害、治疗和康复支持干预措施， 物质使用障碍和疼痛存在，但它们并不普遍。跨部门传播和 实施（D&I）需要科学的方法来选择和提供有效和高效的 在不同背景下的执行战略。研究收养支持中心的研究和 评价（R&E）核心，与行政、物质使用障碍执行支助协调一致 （SUD-IS）和Pain实施支持（Pain-IS）核心，利用集成的、多学科的、迭代的 提供快速评估、专家技术援助和推动长期采用的方法， 维持循证干预措施。R&E核心的首要目标是提升D&I HD 2A创新项目的能力和长期影响。我们通过以下方式实现这一目标： 标准化的基准信息和对数据、分析和研究翻译需求的按需支持， 所有这些都是为了通过基于科学的融资和政策来利用可持续的变化。我们将提供国家- 在D&I测量、框架、建模和测试/评估方面提供最先进的方法支持， 由R&E核心专家，他们在HHS的四个支柱上进行了广泛的工作。与其他 RASC核心，我们由3个动态阶段指导：1）通过3个阶段评估创新项目的基线D&I能力 2）协助创新项目提高D&I能力，同时支持协调数据 跨项目收集和报告;以及3）ADVANCE创新项目的可持续发展潜力， 扩大规模，并作为D&I研究方法资源，以HD 2A建模和经济 资源中心（MERC）和数据基础设施支持中心（DISC）。R&E核心的一个关键功能是 形成性评价，这是一个分阶段的评价，将纳入人类发展2A内部和整个人类发展2A的经验教训 受赠方，形成性评估报告（第1、3年）侧重于提供见解，以支持及时决策- 由受赠者和NIH进行决策和课程更正，以及最终报告（第5年），重点是为未来提供信息 这类举措。我们还将进行5个快速周转研究项目，旨在生产 解决HD 2A确定的执行或持续存在的持续或新出现的障碍的知识 受赠人。第一年的项目将侧重于保险和其他融资的作用 以及广泛采用阿片类药物使用障碍（MOUD）的报销障碍。 在HD 2A计划内外，我们大胆地寻求为成瘾提供知识和方法， 和疼痛干预领域，最终目标是实现转型和公平的公共卫生福利。

RESEARCH AND EVALUATION CORE: PROJECT SUMMARY/ABSTRACT Although effective primary prevention, harm reduction, treatment, and recovery support interventions for substance use disorders and pain exist, they are not widely available. Crosscutting dissemination and implementation (D&I) scientific methods are required to select and deliver effective and efficient implementation strategies under variable contexts. The Research Adoption Support Center’s Research and Evaluation (R&E) Core, in concert with the Administrative, Substance Use Disorder Implementation Support (SUD-IS) and Pain Implementation Support (Pain-IS) cores, utilizes an integrated, multidisciplinary, iterative approach to provide rapid assessment, expert technical assistance, and advance the long-term adoption and sustainment of evidence-based interventions. The overarching goal of the R&E Core is to elevate the D&I capability and translational long-term impact of the HD2A Innovation Projects. We achieve this via standardized baseline information and on-demand support for data, analytic, and research translation needs, all toward leveraging sustainable change through science-based financing and policies. We will provide state- of-the art methodological support in D&I measurement, frameworks, modeling, and testing/evaluation, guided by R&E Core experts who have conducted extensive work across the four HHS pillars. Aligned with other RASC cores, we are guided by 3 dynamic phases: 1) ASSESS Innovation Projects’ baseline D&I capacity via 3 methods; 2) ASSIST the Innovation Projects in increasing D&I capability, while supporting harmonized data collection and reporting across projects; and, 3) ADVANCE Innovation Projects’ potential for sustainment and scale-up, and serve as the D&I research methodology resource to the HD2A Modeling and Economic Resource Center (MERC) and Data Infrastructure Support Center (DISC). A key function of the R&E core is the formative evaluation, a phased evaluation that will incorporate lessons learned within and across HD2A grantees, with formative evaluation reports (Years 1, 3) focused on providing insight to support timely decision- making and course corrections by grantees and NIH, and a final report (Year 5) focused on informing future initiatives of this kind. We also will conduct 5 Rapid Turnaround Research Projects designed to produce knowledge to address persistent or emerging barriers to implementation or sustainment identified by HD2A grantees. The Year 1 project will focus on the role of insurance coverage and other financing and reimbursement barriers to the widespread adoption of medications for opioid use disorder (MOUD). Within and beyond the HD2A program, we boldly seek to contribute knowledge and methods to the addiction and pain intervention fields with the ultimate goal of transformational and equitable public health benefit.