Religion and support for genomic healthcare: An exploratory study of the US public and faith leaders.

宗教和对基因组医疗保健的支持：对美国公众和信仰领袖的探索性研究。

• 批准号: 10708964
• 负责人: James M Dubois
• 金额: $ 47.39万
• 依托单位: WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-09-22 至 2025-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10708964
• 关键词: Address; Adoption; Adult; Attitude; Belief; Bible; Black Populations; Black race; COVID-19 vaccine; Cessation of life; Characteristics; Christianity; Communities; Data; Education; Educational Status; Ensure; Faith; Faith leader; Frequencies; Genes; Genetic; Genomics; Health Technology; Healthcare; Healthcare Activity; Healthcare Systems; Hispanic Populations; Human; Interview; Knowledge; Learning; Life; Measurement; Messenger RNA; Modeling; Morals; Muslim population group; Muslim religion; National Human Genome Research Institute; Participant; Persons; Play; Population; Prayers; Protestant; Public Health; Qualitative Research; RNA vaccine; Regression Analysis; Religion; Research; Research Methodology; Research Personnel; Risk; Role; Rural Population; Sample Size; Sampling; Scientist; Services; Shapes; Subgroup; Surveys; Technology; ethical, legal, and social implication; experience; follower of religion Jewish; genetic testing; health disparity; innovation; instrument; interest; new technology; prenatal; religious group; response; stakeholder perspectives; stem; stem cell therapy

Project Summary Religion is a primary driver of concerns with genomics and genomic healthcare (GGH). It is vital for research on the ethical, legal, and social implications (ELSI) of genomics to understand the role of religion in shaping public attitudes toward GGH. Ninety percent of the US public believes in some kind of higher power and 55% pray daily. The US public attends religious services at a rate 3 times higher than scientists in the US, who are at risk of misunderstanding the role religion plays in attitudes toward GGH. Further, Black, Hispanic, and rural populations attend religious services more frequently than the general US public. Concerns with GGH activities may lead to lower levels of engagement of GGH, which may in turn contribute to health disparities. This project aims to understand why higher levels of religious practice are associated with greater concerns with GGH activities. Additionally, this project will interview faith leaders to identify how public health genomics might engage faith communities in ways that are respectful and constructive. While some concerns with healthcare technologies may disappear with new information, others stem from worldviews, deep moral commitments, or mistrust of the healthcare system. Engaging religious communities is essential to identify which concerns can be addressed with information, which call for alternative responses, and what alternative responses might look like. Very few models exist for genomic public health engagement with religion, particularly models that directly address value-laden concerns.13,14 This project will achieve two specific aims: 1. Quantitatively examine which aspects of religion explain its influence on support for GGH activities. We will survey 4800 adults in the US to examine the association of religious variables with support for GGH activities such as prenatal genetic testing, gene editing, and mRNA vaccines. We will generate rich descriptive data and explore how and when diverse religious variables predict support for, or opposition to, GGH activities. 2. Explore how genomic public health can engage with religious communities in a way that is respectful and constructive. We will conduct in-depth interviews via Zoom with 180 faith leaders—30 from each of six groups: Evangelical, Mainline Protestant, Historically Black, and Catholic Christianity, Judaism, and Islam. These groups represent the largest religious groups in the US, comprising 90% of those with a religious affiliation. Interviews will explore several different issues: What are their views on GGH activities? Is diversity of opinion on these matters tolerated within their community? To what extent are concerns with GGH activities principled and to what extent might further information be helpful? How might genomic public health engage religious communities in a way that is both respectful and constructive?

项目摘要 宗教是基因组学和基因组医疗保健（GGH）关注的主要驱动力。这对于研究至关重要 关于基因组学的道德，法律和社会影响（ELSI），以了解宗教在塑造塑造中的作用 公众参加GGH。美国公众中有90％相信某种更高的力量和55％ 每天祈祷。美国公众参加宗教服务的速度是美国科学家的3倍 有误解宗教的角色有误解的风险。此外，黑色，西班牙裔和粗糙 人口比美国一般公众更频繁地参加宗教服务。对GGH的关注 活动可能导致GGH的参与度较低，这反过来可能导致健康差异。 该项目旨在了解为什么更高水平的宗教实践与更大的关注有关 进行GGH活动。 此外，该项目将采访信仰领导者，以确定公共卫生基因组学如何参与 信仰社区以尊重和建设性的方式。虽然对医疗保健有一些担忧 技术可能会随着新信息而消失，其他信息源于世界观，深厚的道德承诺， 或对医疗保健系统的不信任。参与宗教社区对于确定哪些问题至关重要 可以用信息来解决，这些信息需要替代响应，以及可能会有什么替代答复 看起来像。很少有用于基因组公共卫生与宗教参与的模型，特别是 直接解决具有价值的问题。13,14该项目将实现两个具体目标： 1。定量检查宗教的哪些方面解释了其对GGH活动的支持的影响。 我们将调查美国4800名成年人，以检查宗教变量的协会与GGH的支持 诸如产前基因检测，基因编辑和mRNA疫苗等活动。我们将产生丰富的描述性 数据并探讨潜水员的宗教变量如何以及何时预测对GGH活动的支持或反对。 2。探索基因组公共卫生如何以一种方式与宗教团体互动 尊重和建设性。我们将通过Zoom与180位信仰领袖进行深入的访谈，30 六个团体中的每一个：福音派新教，历史上黑人和天主教基督教，犹太教， 和伊斯兰教。这些群体是美国最大的宗教团体，完成了90％的人 宗教会员。访谈将探讨几个不同的问题：他们对GGH活动有何看法？是 在其社区中对这些事项的看法多样性？ GGH的关注程度在多大程度上 校长的活动以及在多大程度上可能会有所帮助？基因组公共卫生如何 以一种尊重和建设性的方式吸引宗教团体？