St. Jude Children's Research Hospital - Adolescent Medicine Trials Network for HIV/AIDS Interventions (ATN) Operations and Collaborations Center (UM2 Clinical Trial Optional)

圣犹大儿童研究医院 青少年医学艾滋病毒/艾滋病干预试验网络(ATN)的目标是在7年的资金周期内 开发和实施创新的行为、社区、转化、治疗、杀微生物剂和 针对13-24岁艾滋病毒高危人群和艾滋病毒携带者的疫苗试验，重点是纳入 未成年人。ATN寻找具有创新思维和新颖方法的调查人员向公众发表讲话 青少年面临的健康问题。总部设在孟菲斯的圣裘德·孟菲斯网站联盟(SMSC)位于 在田纳西州的谢尔比县，圣犹大儿童医院有(1)完善的临床和临床研究机构 研究医院(前ATN站点)，(2)保护孟菲斯联盟的长期连接(C2P 超过25个利益相关者(基于社区的组织、非营利性组织、孟菲斯学校、 等)投资于青年的利益和(3)建立了伙伴关系，包括与学术界的伙伴关系(哥伦比亚大学 田纳西州)以及当地的谢尔比县和田纳西州卫生部门。谢尔比县是一个 结束艾滋病疫情优先管辖。SMSC与Westat领导的ATN密切合作 运营与协作中心(OCC)将参与临床试验的开发并提供 临床研究地点(S)、当地实验室能力和研究药房支持，以促进ATN 研究议程。对艾滋病毒高危青年和艾滋病毒携带者进行临床试验 他们的诊断将需要使用SMSC已经证明的创新的招聘方法 并期待在过去的基础上再接再厉。C2P孟菲斯联盟和一个单独的青年社区 咨询委员会将在项目期间发挥重要作用，为临床试验设计提供投入 随着青年参与度和留存时间的临近。

ABSTRACT St. Jude Children's Research Hospital The Adolescent Medicine Trials Network for HIV/AIDS Interventions (ATN) aims over the 7-year funding cycle to develop and conduct innovative behavioral, community-based, translational, therapeutic, microbicide, and vaccine trials in youth ages 13-24 years at-risk for HIV and living with HIV, with a focus on the inclusion of minors. The ATN seeks investigators with innovative thinking and novel approaches to address the public health issues facing adolescents. The St. Jude Memphis Site Consortium (SMSC), based in Memphis located in the Shelby County of TN has (1) a well-established clinical and clinical research facility at St. Jude Children's Research Hospital (former ATN site), (2) A long-standing Connect to Protect Memphis Coalition (C2P Memphis) of over 25 stakeholders (Community Based organizations, Non for Profit Groups, Memphis Schools, etc.) invested in the interests of youth and (3) established partnerships including with academia (University of Tennessee) and the local Shelby County and Tennessee state health departments. Shelby County is an Ending the HIV Epidemic Priority jurisdiction. The SMSC closely collaborating with the Westat led ATN Operations and Collaborations Center (OCC) will participate in the development of clinical trials and provide the clinical research site(s), local laboratory capacity, and investigational pharmacy support to further the ATN Research agenda. Taking the clinical trials to youth at risk of HIV and those living with HIV who are not aware of their diagnosis will require using innovative approaches for recruitment which the SMSC has demonstrated in the past and looks forward to building on. The C2P Memphis Coalition and a separate youth community advisory board will over the project period be instrumental in providing input both for clinical trial design as well as youth engagement and retention approaches.