St. Jude Children's Research Hospital - Adolescent Medicine Trials Network for HIV/AIDS Interventions (ATN) Operations and Collaborations Center (UM2 Clinical Trial Optional)

圣裘德儿童研究医院 - 艾滋病毒/艾滋病干预青少年医学试验网络 (ATN) 运营和合作中心（UM2 临床试验可选）

• 批准号: 10599563
• 负责人: Aditya H Gaur
• 金额: $ 45.66万
• 依托单位: WESTAT, INC.
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-09-22 至 2029-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10599563
• 关键词: AIDS/HIV problem; Academia; Acquired Immunodeficiency Syndrome; Address; Adolescent; Adolescent Medicine; Adolescent Medicine Trials Network; African American population; Age; Area; Arkansas; Behavioral; Black Populations; Cities; Clinic; Clinical Research; Clinical Trials; Clinical Trials Design; Collaborations; Communities; County; Development; Diagnosis; Epidemic; Funding; General Population; Geography; HIV; HIV Infections; Health; Healthcare; Human Resources; Income; Individual; Infection; Infrastructure; Intervention; Intervention Studies; Investigation; Laboratories; Leadership; Minor; Mississippi; Missouri; Names; Persons; Pharmacy facility; Policies; Population; Poverty; Public Health; Radial; Research Infrastructure; Research Personnel; Risk; Saint Jude Children' s Research Hospital; Schools; Site; Strategic Planning; Tennessee; Thinking; Time; United States; Universities; Writing; Youth; base; clinical development; clinical research site; clinical trial implementation; community partnership; comorbidity; design; infection rate; innovation; interest; meetings; metropolitan; microbicide; novel; novel strategies; operation; pandemic disease; prevent; recruit; research facility; rural area; translational therapeutics; urban area; vaccine trial; virtual

ABSTRACT St. Jude Children's Research Hospital The Adolescent Medicine Trials Network for HIV/AIDS Interventions (ATN) aims over the 7-year funding cycle to develop and conduct innovative behavioral, community-based, translational, therapeutic, microbicide, and vaccine trials in youth ages 13-24 years at-risk for HIV and living with HIV, with a focus on the inclusion of minors. The ATN seeks investigators with innovative thinking and novel approaches to address the public health issues facing adolescents. The St. Jude Memphis Site Consortium (SMSC), based in Memphis located in the Shelby County of TN has (1) a well-established clinical and clinical research facility at St. Jude Children's Research Hospital (former ATN site), (2) A long-standing Connect to Protect Memphis Coalition (C2P Memphis) of over 25 stakeholders (Community Based organizations, Non for Profit Groups, Memphis Schools, etc.) invested in the interests of youth and (3) established partnerships including with academia (University of Tennessee) and the local Shelby County and Tennessee state health departments. Shelby County is an Ending the HIV Epidemic Priority jurisdiction. The SMSC closely collaborating with the Westat led ATN Operations and Collaborations Center (OCC) will participate in the development of clinical trials and provide the clinical research site(s), local laboratory capacity, and investigational pharmacy support to further the ATN Research agenda. Taking the clinical trials to youth at risk of HIV and those living with HIV who are not aware of their diagnosis will require using innovative approaches for recruitment which the SMSC has demonstrated in the past and looks forward to building on. The C2P Memphis Coalition and a separate youth community advisory board will over the project period be instrumental in providing input both for clinical trial design as well as youth engagement and retention approaches.

摘要圣裘德儿童研究医院 青少年医学试验网络艾滋病毒/艾滋病干预措施（ATN）在7年的资金周期中的目标 开发和进行创新的行为，基于社区，转化，治疗性，菌心和 13-24岁的艾滋病毒和艾滋病毒生活的青年疫苗试验，重点是纳入 未成年人。 ATN寻求以创新思维和新颖的方式向公众讲话的调查员 青少年面临的健康问题。位于孟菲斯的圣裘德孟菲斯网站财团（SMSC） 在田纳西州的谢尔比县（1）圣裘德儿童教育机构有一个完善的临床和临床研究机构 研究医院（前ATN站点），（2）一个长期连接以保护孟菲斯联盟（C2P） 孟菲斯（孟菲斯）超过25个利益相关者（基于社区的组织，非盈利群体，孟菲斯学校， 等等）投资于青年的利益和（3）建立的合作伙伴关系，包括与学术界（大学 田纳西州）以及当地的谢尔比县和田纳西州卫生部门。谢尔比县是 结束HIV流行优先管辖权。 SMSC与Westat Led ATN紧密合作 运营与合作中心（OCC）将参与临床试验的开发并提供 临床研究地点，地方实验室能力和研究性药房支持，以进一步 研究议程。将临床试验带给患有艾滋病毒风险的年轻人和患有艾滋病毒的人 他们的诊断将需要使用SMSC证明的创新方法进行招聘 过去，期待着建设。 C2P孟菲斯联盟和一个独立的青年社区 在整个项目期间，顾问委员会也将在提供临床试验设计的投入方面发挥作用 随着青年参与和保留的临近。