Postdoctoral Training in Cardiovascular Clinical Research

描述(由申请人提供)： 这一修订的NRSA应用程序的首要目标是为那些有潜力成为下一代思想领袖的未来临床心血管研究人员提供高质量的指导培训体验。拟议的培训计划将使我们能够吸引最好的博士后研究员进入临床研究，并确保这些研究员在完成培训后在学术界保持较高的保留率。通过实现该计划的目标，我们将解决培养学术临床研究人员的国家优先事项，这些研究人员可以在从长凳到床边的一系列研究优先事项中填补关键角色，包括翻译研究人员以及临床试验和结果研究人员。 NRSA心血管临床研究培训计划的三个目标是为学员提供：1)临床研究方法的教学培训，2)有指导的研究体验，以及3)成功学术生涯所需的“生存技能”的培训和体验。学员将在这个项目中花费至少两年的时间，并在项目期间100%地投入到项目中。我们正在申请6个博士后级别的实习生职位。对参与计划的导师进行关于良好指导的基本要素的正式培训将是我们计划的一个主要特点。将鼓励跨学科的共同指导。代表杜克大学5个系(内科、外科、麻醉学、儿科、行为医学/精神病学)的21名教职员工将作为导师参加这个项目。它们被组织成三个一般的研究轨道：转译(以患者为中心)、临床试验和结果。这三条路线将通过所选择的教学课程作业计划和为每个受训者创建的定制指导研究计划来区分。在每次研究金的过程中，将使用几种方法来监测进展情况，包括每个研究员与计划主任每季度举行一次会议。每一位研究员所期望的结果都被纳入其中 将用于评估进展的NRSA计划将包括在杜克大学研究会议和全国会议上的演讲、同行评议的出版物，以及至少一项支持学员奖学金后研究的拨款申请。项目主任和教职员工将特别重视帮助每个研究员在学术领域获得奖学金后的教职员工职位，以使他们的研究工作得以继续。项目毕业生还将受到年度联系的监督，以确保继续取得成功并建立稳定的学术生涯。拟议的NRSA计划将把杜克大学可用于临床研究的丰富资源组织成一个有重点的、有效的计划，以培训未来的临床心血管思想领袖。

DESCRIPTION (provided by applicant): The overarching goal of this revised NRSA application is to provide a high quality mentored training experience for those future clinical cardiovascular researchers who have the potential to become the thought leaders of the next generation. The proposed training program will allow us to attract the best post-doctoral fellows into clinical research and ensure a high rate of retention of these fellows in academics after completion of training. By achieving the goal of the program, we will address the national priority of developing academic clinical researchers who can fill vital roles along the gamut of research priorities from bench to bedside, and include translational researchers as well as clinical trialists and outcomes researchers. The three objectives of this NRSA training program in clinical cardiovascular research are to provide trainees with: 1) didactic training in the methods of clinical research, 2) a mentored research experience, and 3) training and experience in "survival skills" required for a successful academic career. Trainees will spend at least 2 years in this program and devote 100% effort to the program while they are in it. We are requesting 6 trainee slots at the post-doctoral level. Formal training of participating mentors on the essentials of good mentoring will be a major feature of our program. Interdisciplinary co-mentoring will be encouraged. Twenty-one faculty representing 5 Departments at Duke (Medicine, Surgery, Anesthesiology, Pediatrics, Behavioral Medicine/Psychiatry) will participate as mentors in this program. They are organized into three general research tracks: translational (patient-oriented), clinical trials, and outcomes. These three tracks will be distinguished by the program of didactic course work chosen and the customized mentored research program created for each trainee. During the course of each fellowship, several methods will be used to monitor progress, including quarterly meetings for each fellow with the Program Director. Outcomes expected from each fellow accepted into this NRSA program that will be used to assess progress will include presentations at Duke research conferences and at national meetings, peer-reviewed publications, and at least one grant application to support the trainee's post-fellowship research. Particular emphasis will be given by the Program Director and faculty to assisting each fellow to obtain a post-fellowship faculty position in academics that will allow continuation of their research work. Program graduates will also be monitored with annual contacts to ensure continued success and establishment of a stable academic career. The proposed NRSA program will organize the abundant resources available at Duke for clinical research into a focused and efficient program for training the clinical cardiovascular thought leaders of the future.