WUSTL Transdisciplinary Pre- and Postdoctoral Training Program in Obesity and Cardiovascular Disease

WUSTL 肥胖与心血管疾病跨学科博士前和博士后培训项目

• 批准号: 9265118
• 负责人: Denise Ella Wilfley
• 金额: $ 50.16万
• 依托单位: WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-07-01 至 2021-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9265118
• 关键词: Cardiovascular Diseases; Obesity; Training Programs; post-doctoral training

 DESCRIPTION (provided by applicant): The complexities of biological, behavioral, social, and environmental risk factors for obesity and cardiovascular disease (CVD) necessitate team science, capable of crossing the boundaries of disciplinary-specific silos to conduct and evaluate research from a transdisciplinary approach to prevent and treat obesity and CVD across the lifespan. Efforts to facilitate greater collaboration among scientists trained across many fields and levels of training are not only valuable but essential to solving such complex problems. Thus, we propose an innovative, transdisciplinary pre- and postdoctoral training program in obesity and CVD at Washington University in St. Louis (WUSTL). WUSTL is a world-class research institution promoting transdisciplinary, translational research through its unique, collegial, scientific environment across campuses and departments. This program will: 1) recruit and train talented transdisciplinary pre- and postdoctoral trainees; 2) provide trainees with collaborative, transdisciplinary mentorship teams; 3) target diversity in the future scientific workforce; and 4) provide training in the ethical and socially responsible conduct of obesity/CVD research. International authorities on obesity, Denise Wilfley, PhD (Director) and Samuel Klein, MD (Co-Director), will lead the program, supported by highly- qualified, primary and co-mentors spanning 15 departments in the biomedical, cognitive and behavioral, and population health sciences. Primary mentors have been extremely successful in training productive scientists; over the last 10 years, 78% and 87% of past pre- and postdoctoral trainees, respectively, are in research careers or training. Of those in research, 67% and 72% have obtained external funding. Our mentors are well funded (93% with NIH funding) and have strong collaborative ties to facilitate the training of 4 pre- and 4 postdoctoral trainees. Combining pre- and postdoctoral trainees from diverse backgrounds (e.g., genetics, molecular cell biology, psychology, social work, public heath, neurosciences) creates a uniquely dynamic training environment. The WUSTL Nutrition Obesity Research Center, Institute of Clinical and Translational Sciences, Institute for Public Health, Diabetic Cardiovascular Disease Center, and Center for Diabetes Translation Research will provide infrastructure and state-of-the-art resources to support trainees' engagement in transformative, translational science. Program evaluations conducted by trainees, program administration and collaborative mentorship teams will ensure trainees achieve short- and long-term indicators of productivity positioning them for success in obtaining academic positions and independent grants. The Diversity Advisory Committee will assist in the recruitment and retention of highly qualified trainees from diverse backgrounds. Not only is our proposed training program innovative in its design, but using a team science approach guided by stellar mentors, our trainees will be prepared to create and contribute to transdisciplinary scientific approaches that are more likely to yield innovative solutions to the complex problems of obesity and CVD than research previously conducted by individual scientists within a single disciplinary field. (End of Abstract)

 描述(由申请人提供)：肥胖和心血管疾病(CVD)的生物、行为、社会和环境风险因素的复杂性要求团队科学，能够跨越学科特定筒仓的边界，从跨学科的方法来开展和评估研究，以预防和治疗肥胖和心血管疾病。努力促进在许多领域和培训水平上受过培训的科学家之间加强合作，对于解决这些复杂问题不仅是宝贵的，而且是必不可少的。因此，我们在圣路易斯的华盛顿大学(WUSTL)提出了一个创新的、跨学科的肥胖和心血管疾病博士后和前期培训计划。WUSTL是一家世界级的研究机构，通过其独特的、大学式的、跨校区和院系的科学环境，促进跨学科、转化性研究。该计划将：1)招募和培训有才华的跨学科博士前和博士后学员；2)为学员提供协作的、跨学科的指导团队；3)针对未来科学劳动力的多样性；以及4)提供有关肥胖/心血管疾病研究的伦理和社会责任方面的培训。负责肥胖问题的国际权威人士Denise Wilfley博士(主任)和Samuel Klein医学博士(联席主任)将领导这项计划，并由生物医学、认知和行为科学以及人口健康科学领域的15个部门的高素质初级和共同导师提供支持。初级导师在培养富有成效的科学家方面非常成功；在过去的10年里，过去的博士后和博士后学员中，分别有78%和87%的人从事研究或培训。在参与研究的人员中，67%和72%获得了外部资金。我们的导师资金充足(93%由NIH资助)，并有强大的合作关系，以促进4名博士后和4名博士后学员的培训。将来自不同背景(如遗传学、分子细胞生物学、心理学、社会工作、公共卫生、神经科学)的博士后和博士后学员结合在一起，创造了一个独特的动态培训环境。WUSTL营养肥胖研究中心、临床和翻译科学研究所、公共卫生研究所、糖尿病心血管疾病中心和糖尿病翻译研究中心将提供基础设施和最先进的资源，以支持学员参与变革性、转化性科学。由学员、项目管理和协作指导团队进行的项目评估将确保学员达到短期和长期生产力指标，为他们成功获得学术职位和独立资助奠定基础。多样性咨询委员会将协助招聘和留住来自不同背景的高素质受训人员。我们建议的培训计划不仅在设计上具有创新性，而且使用由优秀导师指导的团队科学方法，我们的受训人员将准备创造并为跨学科科学方法做出贡献，这些方法比以前由单个科学家在单一学科领域内进行的研究更有可能产生针对肥胖和心血管疾病复杂问题的创新解决方案。(摘要结束)