WUSTL Transdisciplinary Pre- and Postdoctoral Training Program in Obesity and Cardiovascular Disease

项目摘要/摘要 肥胖和心血管疾病的生物、行为、社会和环境风险因素的复杂性 疾病(CVD)需要团队科学，能够跨越学科特定竖井的边界 从跨学科的方法进行和评估研究，以预防和治疗肥胖和心血管疾病 生命的长短。努力促进受过多个领域和水平培训的科学家之间更好的合作 培训不仅是有价值的，而且对于解决这些复杂的问题也是必不可少的。因此，我们建议继续 华盛顿在肥胖和心血管疾病方面的创新的、跨学科的博士后和博士后培训计划 圣路易斯大学(WUSTL)。WUSTL是一个促进跨学科发展的优秀研究机构， 通过其独特的、大学式的、跨校园和院系的科学环境进行翻译研究。 该计划：1)招募和培训有才华的跨学科博士后和博士后实习生；2)提供实习生 与协作的、跨学科的指导团队；3)目标是未来科学劳动力的多样性；以及 4)提供关于肥胖/心血管疾病研究的道德和社会责任行为方面的培训。国际 肥胖权威人士Denise Wilfley博士(主任)和Samuel Klein医学博士(联席主任)领导了该项目， 由高素质的初级和联合导师提供支持，这些导师涵盖生物医学、认知和 行为科学和人口健康科学。我们的导师资金雄厚，并与 为每年培训4名博士后和4名博士后提供便利。结合博士后和博士后实习生 来自不同的背景(例如，遗传学、分子细胞生物学、心理学、社会工作、公共卫生和 神经科学)已经并将继续创造一个独特的动态培训环境。WUSTL 营养性肥胖研究中心，临床与翻译科学研究所，公共卫生研究所， 和糖尿病翻译研究中心提供基础设施和最先进的资源来支持 学员对变革性、转化性科学的参与度。学员完成的项目评估， 项目管理和协作指导团队确保学员实现短期和长期目标 生产力指标使他们能够成功地获得学术职位和独立补助金。 事实上，该项目的博士后毕业生在获得学术职位方面非常成功 并提供资金，对于我们的博士前实习生来说，继续他们在著名的 各就各位。多样性咨询委员会告知我们在招聘和保留高级人才方面的做法 来自不同背景的合格学员。我们的培训计划不仅在设计上有创新，而且 使用团队科学的方法，在优秀导师的指导下，我们的学员准备创造和 促进跨学科的科学方法，更有可能产生创新的解决方案 肥胖和心血管疾病的复杂问题，而不是以前由个别科学家在一个 单一学科领域。

PROJECT SUMMARY/ABSTRACT The complexities of biological, behavioral, social, and environmental risk factors for obesity and cardiovascular disease (CVD) necessitate team science, capable of crossing the boundaries of disciplinary-specific silos to conduct and evaluate research from a transdisciplinary approach to prevent and treat obesity and CVD across the lifespan. Efforts to facilitate greater collaboration among scientists trained across many fields and levels of training are not only valuable but also essential to solving such complex problems. Thus, we propose to continue an innovative, transdisciplinary pre- and postdoctoral training program in obesity and CVD at Washington University in St. Louis (WUSTL). WUSTL is an excellent research institution promoting transdisciplinary, translational research through its unique, collegial, scientific environment across campuses and departments. This program: 1) recruits and trains talented transdisciplinary pre- and postdoctoral trainees; 2) provides trainees with collaborative, transdisciplinary mentorship teams; 3) targets diversity in the future scientific workforce; and 4) provides training in the ethical and socially responsible conduct of obesity/CVD research. International authorities on obesity, Denise Wilfley, PhD (Director) and Samuel Klein, MD (Co-Director), lead the program, supported by highly- qualified, primary and co-mentors spanning 12 departments in the biomedical, cognitive and behavioral, and population health sciences. Our mentors are well-funded and have strong collaborative ties to facilitate the training of 4 pre- and 4 postdoctoral trainees each year. Combining pre- and postdoctoral trainees from diverse backgrounds (e.g., genetics, molecular cell biology, psychology, social work, public heath, and neurosciences) has created and will continue to create a uniquely dynamic training environment. The WUSTL Nutrition Obesity Research Center, Institute of Clinical and Translational Sciences, Institute for Public Health, and Center for Diabetes Translation Research provide infrastructure and state-of-the-art resources to support trainees' engagement in transformative, translational science. Program evaluations completed by trainees, program administration, and collaborative mentorship teams ensure trainees achieve short- and long-term indicators of productivity positioning them for success in obtaining academic positions and independent grants. Indeed, postdoctoral graduates of the program have been highly successful in obtaining academic positions and grant funding, and in the case of our predoctoral trainees, continuing their research training in prestigious positions. The Diversity Advisory Committee informs our approach in the recruitment and retention of highly qualified trainees from diverse backgrounds. Not only is our training program innovative in its design, but using a team science approach guided by stellar mentors, our trainees are prepared to create and contribute to transdisciplinary scientific approaches that are more likely to yield innovative solutions to the complex problems of obesity and CVD than research previously conducted by individual scientists within a single disciplinary field.