Training Grant in CVD Genetic Epidemiology

CVD遗传流行病学培训补助金

• 批准号: 6769472
• 负责人: JAMES S PANKOW
• 金额: $ 10.75万
• 依托单位: UNIVERSITY OF MINNESOTA
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-07-16 至 2006-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6769472
• 关键词: Training; Grant; CVD; Genetic; Epidemiology

(Applicant?s Abstract) The genetic basis of cardiovascular diseases (CVD) and its related phenotypes is poorly defined. Advancements in the fields of molecular and statistical genetics have greatly enhanced our ability to understand the genetic etiology of complex diseases, like CVD. Several CVD genetic epidemiological studies have a wealth of well-characterized genotypic, environmental, and phenotypic data available. The Human Genome Project will have the sequence of human genomic DNA completed by 2003, an currently has abundance of data and resources to conduct analyses related to genetic and genomic contributions to CVD. There is a great demand for scientists that successfully integrate various types of data (genetic, environmental, and phenotypic). Genetic epidemiologist, rigorously trained in epidemiologic methods, statistics, and genetics are urgently needed to expand research opportunities in this emerging field. This five-year proposal, if awarded, will provide training for 3 pre-doctoral fellows and 1 post-doctoral fellowship positions. The demand for pre-doctoral fellowships, based on recent applicants to the Ph.D. program in the Division, is increasing. In addition, we currently have excellent pre-doctoral and post-doctoral candidates who would be eligible for a fellowship if the proposal is funded. The Program?s excellent facilities, large and diverse faculty, and broad research opportunities offer an outstanding training environment. The University of Minnesota two to three year fellowship program offers outstanding training opportunities in direct research experience in genetic epidemiology combined with a strong curriculum of formal course work and seminars. The participation of women and minorities is a high priority for fellowship training. The uniqueness of the training is the commitment of its faculty and the breadth and depth of existing research in family-based studies in CVD, and the combination of coursework in population, molecular, and statistical genetics. The need for qualified CVD genetic epidemiologists is urgent, and the training of scientists for research careers in CVD genetic epidemiology will help to further understanding of the complex genetic etiology of CVD. (End of Abstract)

（申请人的摘要） 心血管疾病（CVD）的遗传基础及其相关表型 定义不明确。分子和统计学领域的进展 遗传学极大地增强了我们理解遗传病因学的能力 复杂疾病，如心血管疾病。多项CVD遗传流行病学研究 具有丰富的特征明确的基因型、环境和表型 可用数据。人类基因组计划将拥有人类的序列 基因组 DNA 于 2003 年完成，目前拥有丰富的数据和 进行与遗传和基因组贡献相关的分析的资源 化学气相沉积。对成功整合的科学家的需求很大 各种类型的数据（遗传、环境和表型）。遗传 流行病学家，接受过流行病学方法、统计学和严格培训 迫切需要遗传学来扩大这一新兴领域的研究机会 场地。 这项为期五年的提案如果获得批准，将为 3 名博士生提供培训 研究员和1个博士后研究员职位。博士前的需求 奖学金，基于最近的博士学位申请者。该部门的计划， 正在增加。此外，我们目前拥有优秀的博士前和 有资格获得奖学金的博士后候选人，如果 提案得到资助。该计划的设施优良，规模宏大且多样化 师资力量和广泛的研究机会提供了出色的培训 环境。 明尼苏达大学提供两到三年的奖学金计划 遗传直接研究经验的出色培训机会 流行病学与强大的正式课程相结合 研讨会。妇女和少数族裔的参与是该组织的高度优先事项 联谊培训。培训的独特性在于其承诺 师资力量以及现有家庭研究研究的广度和深度 CVD 课程，以及人口、分子和疾病课程的结合 统计遗传学。需要合格的 CVD 遗传流行病学家 迫切需要对科学家进行 CVD 遗传研究职业培训 流行病学将有助于进一步了解复杂的遗传因素 CVD的病因学。 （摘要完）