All Digital Home Use System for Mole Monitoring

用于鼹鼠监测的全数字家庭使用系统

• 批准号: 6735761
• 负责人: Eric R. Craine
• 金额: $ 7万
• 依托单位: WESTERN RESEARCH COMPANY, INC.
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-09-01 至 2005-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6735761
• 关键词: bioimaging /biomedical imaging; clinical research; computer assisted diagnosis; computer program /software; computer system design /evaluation; diagnosis design /evaluation; digital imaging; early diagnosis; human subject; image processing; neoplasm /cancer diagnosis; neoplastic transformation; patient oriented research; pigmented nevus; preneoplastic state; self care; skin neoplasms

DESCRIPTION (provided by applicant): The incidence of skin cancer and melanoma continues to rise rapidly in the United States. The best defense against often-fatal melanoma is early detection of the disease, a task that is aided by early detection of new or changed pigmented moles. The medical community relies heavily upon patient input to assess these early stage changes. A major education effort to make people aware of the problem, and the need for aggressive skin self-screening has been very successful at raising awareness and interesting individuals in participating in such screening. Nonetheless, this activity has proven difficult to accomplish effectively, even for highly motivated individuals. We propose development of a highly refined, all digital, completely portable, low cost imaging tool which can dramatically improve the ability of people to assist in finding new and changed pigmented moles at home. Currently available imaging systems for home use, while very effective, require use of a film-based image and tie the patient to a nearby imaging service. Recent improvements in consumer grade digital cameras, and their widespread proliferation, suggest that product availability, ease of use, greater privacy and higher patient compliance may be attainable for personal skin imaging through development of an all digital personal skin screening system. The goal of this Phase I project is to create and evaluate such a tool, and to prepare for a Phase II clinical study, which will address the efficacy of this type of skin monitoring.

描述(由申请人提供)： 皮肤癌和黑色素瘤的发病率在美国持续快速上升。对往往致命的黑色素瘤的最好防御是及早发现这种疾病，这项任务辅之以及早发现新的或变化的色素痣。医学界在很大程度上依赖患者的意见来评估这些早期变化。一项重大的教育努力使人们意识到这个问题，并需要积极的皮肤自我筛查，这在提高人们的意识和参与此类筛查的有趣个人方面非常成功。尽管如此，事实证明，这项活动很难有效完成，即使是对积极性很高的人来说也是如此。我们建议开发一种高度精致的、全数字的、完全便携的、低成本的成像工具，它可以极大地提高人们在家里帮助寻找新的和变化的色素痣的能力。目前可用的家用成像系统虽然非常有效，但需要使用基于胶片的图像，并将患者与附近的成像服务捆绑在一起。消费级数码相机的最新改进及其广泛的普及表明，通过开发全数字个人皮肤筛选系统，个人皮肤成像可以获得产品可用性、易用性、更大的隐私和更高的患者依从性。这个第一阶段项目的目标是创建和评估这种工具，并为第二阶段临床研究做准备，该研究将解决这种类型的皮肤监测的有效性。