Upper Limb Musculosketal Disorders: Quantifying Risk

上肢肌肉骨骼疾病：量化风险

• 批准号: 6775566
• 负责人: ARUN GARG
• 金额: $ 49.91万
• 依托单位: UNIVERSITY OF WISCONSIN MILWAUKEE
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-09-30 至 2006-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6775566
• 关键词: clinical research; cooperative study; disease /disorder proneness /risk; epidemiology; human subject; interview; limbs; longitudinal human study; musculoskeletal disorder; musculoskeletal disorder diagnosis; occupational hazard; occupational stressor; questionnaires

DESCRIPTION: This multi-center prospective cohort study will: (i) Determine baseline prevalence rates and subsequent incidence rates over a 3 year period for specific distal upper extremity disorders and symptoms for 3 levels of job physical exposures (low, medium, high), (ii) Quantify job and individual risk factors (e.g., force, posture, repetition, etc.), (iii) Validate existing job analysis methods (especially American Conference of Governmental Hygienists (ACGIH) Threshold Limit Value (TLV) for Hand Activity (HAL), Strain Index (SI) and Washington State Checklist), and (iv) develop a final model for determining MSD risks. A cohort of 600 workers (study drop-outs replaced) from 5 very different industries with a total worker population of over 10,000 in two diverse states will participate in the study to help ensure generalizability of the study results. To maximize objectivity and accuracy, job physical exposures will rely primarily on measurements to quantify exposures. To maximize clinical and epidemiological validity and reliability, all participants will have health outcomes assessments by Certified Hand Therapists and qualified physicians. These will include: baseline questionnaires, structured interviews and standardized physical examinations. Changes in job physical exposures will be monitored monthly. Specific disorders and symptoms will be assessed monthly using a symptom questionnaire on all, and structured interviews/physical examinations on those with symptoms. Senior physicians experienced in evaluating worker populations will provide electrodiagnostic testing (at baseline, and during monthly follow-up if new symptoms develop) to those workers with CTS-like symptoms. Job physical exposure and health outcomes assessment teams will be blinded to each other throughout the field observation phase. Multivariate logistic regression (MLR) models and survival analyses will be utilized to explore relationships between job physical risk factors and specific disorders, aggregate disorders and symptoms. In addition to quantifying ergonomic risk factors, interactions between various job, psychosocial and individual risk factors will be explored. This project is expected to result in the ability to improve the existing ergonomic job evaluation models that have robust predictive capabilities for a broad range of industries.

DESCRIPTION: This multi-center prospective cohort study will: (i) Determine baseline prevalence rates and subsequent incidence rates over a 3 year period for specific distal upper extremity disorders and symptoms for 3 levels of job physical exposures (low, medium, high), (ii) Quantify job and individual risk factors (e.g., force, posture, repetition, etc.), (iii) Validate existing job analysis methods (especially American Conference of Governmental Hygienists （ACGIH）手活动（HAL），应变指数（SI）和华盛顿州清单）的阈值极限值（TLV），以及（iv）开发用于确定MSD风险的最终模型。 来自5个截然不同的行业的600名工人（替代了研究辍学者）的队列将参与研究，以确保研究结果的普遍性。 为了最大程度地提高客观性和准确性，工作身体暴露将主要依赖于测量来量化暴露。 为了最大程度地提高临床和流行病学的有效性和可靠性，所有参与者将对经过认证的手动治疗师和合格医生进行健康结果。 这些将包括：基线问卷，结构化访谈和标准化的身体检查。 工作身体暴露的变化将每月监控。 特定的疾病和症状将每月使用症状问卷调查评估，并对患有症状的人进行结构化访谈/身体检查。 评估工人人群的高级医师将为那些患有类似CTS症状的工人提供电诊断测试（基线时，如果在新症状出现的情况下进行新症状）。 在整个现场观察阶段，工作的身体暴露和健康成果评估团队将彼此视而不见。 多元逻辑回归（MLR）模型和生存分析将用于探索工作物理风险因素与特定疾病，整体疾病和症状之间的关系。 除了量化符合人体工程学的风险因素外，还将探讨各种工作，社会心理和个人风险因素之间的相互作用。 预计该项目有望提高现有的符合人体工程学的工作评估模型，这些模型具有强大的预测能力，可为广泛的行业提供强大的预测能力。