Upper Limb Musculoskeletal Disorders: Quantifying Risk

上肢肌肉骨骼疾病：量化风险

• 批准号: 7280459
• 负责人: ARUN GARG
• 金额: $ 47.95万
• 依托单位: UNIVERSITY OF WISCONSIN MILWAUKEE
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-09-30 至 2009-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7280459
• 关键词: Upper; Limb; Musculoskeletal; Disorders; Quantifying

DESCRIPTION (Provided by applicant): This proposal is a request for continuation of our multi-center, prospective cohort study that previously focused solely on Distal Upper Extremity (DUE) Disorders. The original study was in response to RFA OH-02-010 and involved 600+ workers in two diverse states. The study was funded for 4 years, ending September 2006. We are following 600+ workers in low (n=251), medium (n=249) and high (n=197) job physical exposure groups from 15+ different industries to improve generalizability of the study results. Preliminary analyses of the data suggest that our original objectives of the study will be met by September 2006. This proposed continuation application is for 3 additional years (seven years total). The main purposes of this continuing application are to: (1) continue monitoring upper limb disorders in this cohort for an additional 2.25 years to develop sufficient power to identify interactions within arid between job physical, individual and psychosocial factors, and (2) determine baseline prevalence rates and subsequent incidence rates over a 2.25 year period for specific shoulder disorders and symptoms for a broad range of exposures (initially classified as low, medium, and high). In addition to the original aims, this multi-center prospective cohort study will (1) study interactions within and between various risk factors (e.g. individual, psychosocial, and job physical factors) to better quantify risks for DUE musculoskeletal disorders (MSDs), (2) develop a comprehensive job analysis model including interactions for determining risk for DUE MSDs, (3) validate existing shoulder job analysis models (which are primarily based on posture), and (4) develop a comprehensive shoulder job analysis model for determining risk of shoulder MSDs. Job physical exposures primarily rely on measurements to quantify exposures to maximize objectivity and accuracy, while also utilizing methods that are practical and readily usable in industry [Research to Practice (r2p)]. All participants have health outcomes assessments by Certified Hand Therapists and qualified physicians. All subjects have: (i) baseline questionnaires, (ii) structured interviews, (iii) standardized physical examinations and (iv) nerve conduction studies (NCS). Changes in job physical exposures are monitored quarterly. Specific disorders and symptoms are assessed monthly on all participants using structured interviews and physical examinations. Those with paresthesias receive a follow-up NCS. Both Job Physical Exposure and Health Outcomes Assessment Teams are blinded to the other team. Multivariate logistic regression models and survival analyses will be utilized to explore relationships between risk factors (job physical, psychosocial and individual) and specific disorders, aggregate disorders and symptoms. In addition to quantifying ergonomic risk factors, interactions within and between various job physical, psychosocial and individual risk factors will be explored. This project is expected to result in DUE and shoulder job analysis models that have robust predictive capabilities for a broad range of jobs.

描述（由申请人提供）：该提案是延续我们多中心的前瞻性队列研究的请求，该研究以前仅着眼于远端上肢（应得的）疾病。最初的研究是针对RFA OH-02-010的回应，并涉及两个不同州的600多名工人。这项研究的资金为4年，截至2006年9月。我们关注了600多名低点（n = 251），中（n = 249）和高（n = 197）的工作身体暴露组，来自15个以上不同行业，以提高研究结果的普遍性。对数据的初步分析表明，我们的研究最初目标将在2006年9月之前实现。拟议的延续申请是另外3年（总计七年）。这种持续应用的主要目的是：（1）继续监测该队列中的上肢疾病，再进行2。25年的其他2.25年，以开发足够的能力，以确定在工作，个人和社会心理因素之间在工作中进行互动，（（2）确定在2.25年度的较高范围内，在2.25年的较高范围内，确定基线的流行率和随后的频率为较低的范围，并且是在较宽的范围内，并且是较宽的范围（以较宽的范围），并且在较宽的范围内（培养范围），并逐渐形成较大的范围（均为型号）。除了最初的目标外，这项多中心的前瞻性队列研究还将（1）研究在各种风险因素（例如个人，心理社会和工作身体因素）之间和之间的研究相互作用，以更好地量化适当的肌肉骨骼疾病（MSDS）（MSD）（MSD）的风险（2），（2）建立了对较高的工作分析的全面相互作用，包括对近MSD的互动（3）（3）（3）（3）（3）（3）（3）（3）（3）（3）（3）（3）（3）（3）（3）（3）（3）（3）（3）（3）（3）（3）（3）（3）（3）（3）（3）（3）（3） （4）开发一个综合的肩部工作分析模型，用于确定肩部MSD的风险。工作物理暴露主要依赖于测量来量化暴露以最大程度地提高客观性和准确性，同时还利用在行业中实用且易于使用的方法[实践研究（R2P）]。所有参与者都有经过认证的手动治疗师和合格医生的健康结果评估。所有受试者均具有：（i）基线问卷，（ii）结构化访谈，（iii）标准化的身体检查和（iv）神经传导研究（NCS）。每季度监控工作身体暴露的变化。使用结构化的访谈和身体检查，每月对所有参与者评估特定的疾病和症状。那些具有感觉的人会接受随访的NCS。工作身体曝光和健康成果评估团队都对另一个团队视而不见。多元逻辑回归模型和生存分析将用于探索风险因素（工作身体，社会心理和个人）与特定疾病，总体疾病和症状之间的关系。除了量化符合人体工程学的风险因素外，还将探索各种工作，心理社会和个人风险因素之间的相互作用。预计该项目将导致适当的和肩部的工作分析模型，这些模型具有强大的预测能力，可以为广泛的工作提供。