OREGON NODE - NATIONAL CLINICAL TRIALS NETWORK

俄勒冈节点 - 国家临床试验网络

• 批准号: 6889324
• 负责人: DENNIS MCCARTY
• 金额: $ 6.81万
• 依托单位: OREGON HEALTH & SCIENCE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-09-30 至 2005-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6889324
• 关键词: antidepressants; behavior therapy; behavioral /social science research tag; clinical research; clinical trials; community mental health services; cooperative study; drug abuse chemotherapy; drug abuse therapy; health care model; health services research tag; human subject; human therapy evaluation

This proposal calls for the creation of the Oregon Regional Node (OR- Node) of NIDA's national drug treatment clinical trials network on the basis of an Oregon consortium of the researchers, community treatment programs and the state policy group for substance abuse treatment. This consortium, "Oregon Bridging the Gap Between Practice and Research: Forging Partnerships with Community-Based Drug and Alcohol Treatment (Lamb, Greenlick, and McCarty). The proposed OR-Node is a partnership of three research and training organizations, more than 30 collaborating investigators, and the treatment provider community of the State of Oregon. The research group brings resources from the Oregon Health Sciences University, the Kaiser Permanente Center for Health Research, and the Oregon Research Institute. Investigators and operations personnel from these institutions will form the Regional Research and Training Center (RRTC) of OR-Node. Each of these centers of excellence provides senior research personnel to OR-NODE and each brings a special set of other resources to the partnership, such as the approaches and institutional settings, and provides treatment services to all segments of the Oregon population. The structure of the OR-Node operationalizes a full partnership arrangements among the research institutions and the treatment community. Three research concepts are offered in this proposal, selected to exhibit the full-range of research that can be carried out by the OR-Node researchers and the type of resources OR-Node offers to the national network. The research concepts are: a quantitative and qualitative assessment of the national network treatment programs developing and testing a model of diffusion of innovation among community-based treatment programs, a clinical trial of antidepressants as an adjuvant in behavioral treatment for drug abuse, and a project top enhance the recruitment and treatment of persons with mild or moderate mental retardation with drug abuse or dependency problems.

该提案要求在俄勒冈州研究人员、社区治疗方案和药物滥用治疗国家政策小组联合会的基础上，建立NIDA国家药物治疗临床试验网络的俄勒冈州区域节点。这个联盟，“俄勒冈州弥合实践和研究之间的差距：与社区为基础的药物和酒精治疗（兰姆，格林利克和麦卡蒂）锻造伙伴关系。拟议的OR节点是三个研究和培训组织，30多个合作研究人员和俄勒冈州的治疗提供者社区的合作伙伴关系。该研究小组带来了来自俄勒冈州健康科学大学、凯撒永久健康研究中心和俄勒冈州研究所的资源。这些机构的研究人员和操作人员将组成OR-Node的区域研究和培训中心（RRTC）。每个卓越中心都为OR-NODE提供高级研究人员，每个中心都为伙伴关系带来一套特殊的其他资源，如方法和机构设置，并为俄勒冈州人口的所有部分提供治疗服务。OR节点的结构在研究机构和治疗界之间实现了全面的伙伴关系安排。本提案中提供了三个研究概念，选择这些概念是为了展示OR-Node研究人员可以进行的全方位研究以及OR-Node向国家网络提供的资源类型。研究概念是：对国家网络治疗方案进行定量和定性评估，制定和测试在社区治疗方案中推广创新的模式，进行抗抑郁药作为药物滥用行为治疗辅助剂的临床试验，以及一个旨在加强招募和治疗有药物滥用或依赖问题的轻度或中度智力迟钝者的项目。