Administration Core

摘要（核心A） 鉴于我们的多站点计划项目的复杂性，出色的管理结构至关重要。的 行政核心（核心A）的总体目标是促进智力、财务和后勤协同作用 包括所有项目、核心和分包商。除了促进研究者互动外，核心A还将 提供方案指导，评估科学进展，并提供行政和预算支持 整个计划。它还将为个别项目和核心领导人提供适当的咨询意见 财政监督。核心将由W. Sean Davidson，该项目的首席研究员 项目补助金，与项目协调员合作。该资源将通过以下方式实现其目标： 目标：1）为所有项目和核心提供行政和财政援助，2）促进整个计划 使用最新的多研究者会议技术进行通信，3）提供预算监督， 该计划，并确保遵守联邦法规，4）管理分包合同，以提供科学和 为人类研究提供生物统计支持，并为亚拉巴马大学的一名合作研究人员提供生物统计支持， 伯明翰，5）组织内部和外部咨询委员会会议，6）提供 与NHLBI的通信接口。该方案在上一个周期取得的显著成功表明， 核心A的设计和我们整合项目的方法的有效性。受益于此 经验，核心A是唯一有资格在第二个周期管理该计划。

SUMMARY (Core A) Given the complexity of our multi-site Program Project, an outstanding administrative structure is critical. The overarching goal of Administrative Core (Core A) is to promote intellectual, financial and logistical synergy across all projects, cores and subcontractors. In addition to facilitating investigator interactions, Core A will provide programmatic direction, evaluate scientific progress, and provide administrative and budgetary support to the entire Program. It will also provide individual Project and Core Leaders with appropriate advisory input and fiscal oversight. The core will be led by W. Sean Davidson, the Principal Investigator of this Program Project Grant, working with the Program Coordinator. The resource will meet its goals by pursuing the following objectives: 1) Provide administrative and fiscal assistance to all Projects and Cores, 2) facilitate program-wide communication using the latest in multi-investigator conferencing technology, 3) provide budgetary oversight of the Program and ensure compliance with federal regulations, 4) manage subcontracts to provide scientific and biostatistical support for human studies and for a collaborating investigator at the University of Alabama at Birmingham, 5) organize meetings of the internal and external advisory committees, and 6) provide a communication interface with the NHLBI. The Program’s remarkable success in the previous cycle illustrates the effectiveness of Core A’s design and our approach to integrating the Projects. Benefitting from this experience, Core A is uniquely qualified to manage the Program in a second cycle.