Bioinformatics

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Project Summary Bioinformatics Core Vision science, like many fields in biology, is benefitting tremendously from technological advances that make it possible to collect huge amounts of data about genes, proteins, lipids, and cellular structures in intact tissues of the eye and brain. Likewise, advances in functional imaging are making it easier to collect information about activity of neurons in the retina and brain as they are responding to visual images. While Berkeley scientists have tremendous expertise in collecting “big data” sets, many investigators and their labs lack the knowledge, resources, and time to organize, process, and analyze the data to reveal meaningful results. With the entry of a new Vision Science faculty member with great expertise in Bioinformatics and the availability of a great local labor pool of highly astute young expert Data Scientists, we have decided to establish a new Bioinformatics Core that will provide sorely needed to services to Vision Science faculty. The Aims of the Core are 1) to establish cloud-based pipelines for preprocessing, storage and retrieval of high-throughput single-cell transcriptomics and imaging data, 2) develop and maintain bioinformatic pipelines to support downstream analysis of new and publicly available datasets, and 3) provide advisory and training services on bioinformatic methods.