NCATS CLINICAL AND TRANSLATIONAL SCIENCE AWARDS (CTSA) PROGRAM: COORDINATION, COMMUNICATION AND OPERATIONS SUPPORT (CCOS)

CTSA计划的使命是为更多的患者带来更多的治疗方法，更快。在其存在的20多年中，该计划已经发展成为60多个研究中心和核心资源，如试验创新网络。为了帮助管理和凝聚如此庞大的分布式结构，NCATS创建了一个协调中心(CC)，其使命是促进协作科学团队的工作，提供后勤支持，并确保整个网络中的信息无缝流动。目前的CTSA CC是领先创新与合作中心(CLIC)，于2017年授予。 新的CTSA协调、通信和业务支助(CCOS)代表了一种利用合同机制的新方法，该机制使NCATS能够更直接地控制协调委员会的优先事项，并能够灵活和快速地调整重点，以应对CTSA战略优先事项的变化。这种向合同的过渡将带来效率，并使我们能够提供我们认为CTSA所需要的：一个先进的卓越运营中心，将带来可重复使用的流程、卓越的技术以及将数据转化为知识的不懈关注。转型也带来了挑战，我们正在通过组建一个团队来应对这些挑战，团队拥有学术中心的翻译科学资质、CLIC的机构知识、承包商的卓越运营和高度相关的大型NIH研究财团协调中心管理经验。

The mission of the CTSA Program is to bring more therapies to more patients, faster. In its more than two decades of existence, the Program has grown to over 60 research Hubs and core resources such as the Trial Innovation Network. To help manage and bring cohesion to such a large and distributed structure, NCATS created a coordination center (CC) with the mission to facilitate the work of the collaborative scientific teams, provide logistical support, and ensure a seamless flow of information across the network. The current CTSA CC is the Center for Leading Innovation and Collaboration (CLIC), a grant awarded in 2017. The new CTSA CC, the Coordination, Communication and Operations Support (CCOS), represents a new approach that leverages a contract mechanism, which provides NCATS with more direct control over the priorities of the CC and the ability to pivot nimbly and rapidly to address changes in the strategic priorities for the CTSA. This transition to a contract will bring efficiencies and enable us to deliver what we believe the CTSAs need: a state-of-the-art operational center of excellence that will bring to bear reproducible processes, technological excellence, and a relentless focus on transforming data into knowledge. The transition also brings challenges, which we are addressing by assembling a team with the translational sciences credentials of an academic center, the institutional knowledge of CLIC, and the operational excellence of contractors with the highly relevant experience of managing coordinating centers for large NIH research consortia.