Administrative Core

摘要 行政核心的目的是提供领导和行政管理 拟议的多学科P50孢子，旨在利用夏威夷大学的基础设施 癌症中心(UHCC)及其集水区的种族/民族多样性进行翻译研究 解决夏威夷和太平洋地区存在的癌症风险和结果方面的种族/族裔差异。这个 行政核心将建立在许多UCC资源的基础上，包括行政和科学资源，以促进 执行和协调本P50中的研究。这一核心也将密切协调P50 资源建设和职业发展活动与UCC实施的活动相比，因此效率更高 在机构层面上取得的成就。因此，这一核心具有主要的行政和综合职能 格兰特。P50将依靠一个内部咨询委员会(IAC)，该委员会由关键的高级基础和临床 关于癌症差异的研究人员，接受关于研究机会的投入，并促进与 潜在的协同作用的地方倡议。该方案还将受益于社区咨询的投入 委员会(CAB)由社区领导人和患者权益倡导者组成，他们在癌症差异和/或 生存，以及谁将就我们的活动对社区需求和期望的反应提供建议。 方案评估将在很大程度上依赖于由外部组成的外部咨询委员会(EAB)的投入 在孢子和/或癌症健康差异研究方面处于领先地位的调查人员，以及国家认可的 病人代言人。具体目标1将提供全面的科学和行政协调和联合 P50奖助金的领导力。具体目标2将是协调和整合P50活动和 UHCC。具体目标3将是计划和评估当前和未来的转译癌症差异研究 作为P50孢子计划的一部分。行政核心将在支持研究方面发挥重要作用 在P50中提出的方案。我们相信，每一位核心联合领导者和久经考验的 本节介绍的方法将提供基础和构建块来实现我们的 目标。

Abstract The purpose of the Administrative Core is to provide the leadership and administrative management for the proposed multidisciplinary P50 SPORE aimed at capitalizing on the infrastructure at the University of Hawai`i Cancer Center (UHCC) and the racial/ethnic diversity of its catchment area to conduct translational research addressing the racial/ethnic differences in cancer risks and outcomes that exist in Hawai`i and the Pacific. The Administrative Core will build upon a number of UHCC resources, both administrative and scientific, to foster the implementation and coordination of the research in this P50. This Core will also closely coordinate the P50 resource-building and career-development activities with those implemented by UHCC, so greater efficiency is achieved at the institutional level. Thus, this Core serves major administrative and integrative functions for the grant. The P50 will rely on an Internal Advisory Committee (IAC), consisting of key senior basic and clinical researchers on cancer disparities, to receive input on research opportunities and to facilitate coordination with potentially synergistic local initiatives. The program will also benefit from the input of a Community Advisory Board (CAB) composed of community leaders and patient advocates with experience in cancer disparities and/or survivorship, and who will advise on the responsiveness of our activities to community needs and expectations. Program evaluation will heavily rely on the input of an External Advisory Board (EAB) composed of outside investigators who are leaders in SPOREs and/or cancer health disparities research and a nationally-recognized patient advocate. Specific Aim 1 will be to provide the overall scientific and administrative coordination and joint leadership for the P50 grant. Specific Aim 2 will be to coordinate and integrate the P50 activities with those of UHCC. Specific Aim 3 will be to plan and evaluate current and future translational cancer disparities research as part of the P50 SPORE program. The Administrative Core will play an essential role in supporting the research program proposed in the P50. We believe that the skills and experience of each Core Co-Leader and the proven approaches described in this section will provide both the foundation and the building blocks to achieve our goals.