Training Program in Cellular and Molecular Biology and Genetics

细胞和分子生物学和遗传学培训计划

• 批准号: 10715032
• 负责人: CHARLES C QUERY
• 金额: $ 58.36万
• 依托单位: ALBERT EINSTEIN COLLEGE OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-07-01 至 2028-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10715032
• 关键词: Cellular biology; Genetic; Molecular Biology; Training Programs

PROJECT SUMMARY / ABSTRACT The CMBG program trains graduate students for the PhD degree in Cell & Molecular Biology and Genetics. The program includes 54 proposed faculty from 8 basic science departments and is the only graduate training program at the Albert Einstein College with a broad, interdisciplinary research emphasis designed to increase understanding of biological processes and lays the foundation for advances in disease diagnosis, treatment, and prevention. This application replaces a pre-existing program with support for 14 trainees (~7 appointed/year). Over the past 15 years, our CMBG program graduated 84 PhD students, including 25 under-represented minority students. More than 95% of graduates continued in science-related careers. Overall objectives are for students to perform significant basic science research projects, to acquire rigorous scientific background and experimental training, to develop and defend their PhD thesis in a timely manner, and to develop into independent scientists who make long-term contributions in the biomedical sciences. Training faculty are selected based on research excellence in Cell Biology, Molecular Biology, and Genetics, and on their commitment to mentor students and to provide an outstanding and safe training environment. All but ESI faculty members have substantial mentoring experience and funding; mechanisms are in place to assist junior faculty in mentoring students and to provide additional oversight for students in their labs. Trainees enter Einstein through a single Graduate School portal. They receive formal training in the responsible conduct of research and teaching. Students complete 3 research rotations in the first year and undertake rigorous coursework, including CMBG-foundation courses organized and taught by our Assoc. Directors and trainers. Students write a grant proposal-type qualifying exam based on their PhD research and defend it orally to an interdisciplinary faculty committee. Students are reviewed by the CMBG Advisory Committee after the first and second years and interviewed by the Program Director prior to appointment for a proposed 2 years of funding. CMBG program activities build a coherent training effort in which students participate until completion of the PhD. Trainees present their work yearly in an active work-in-progress series and host an annual student-invited exceptional seminar speaker. Annual program retreats include talks by senior students, posters, workshops, discussions of ethics and rigor, and presentations from CMBG alumni to provide career perspectives. At all events, our CMBG trainers, Advisory Committee, Director, and Assoc. Directors provide input on research directions, rigor of the experimental strategy, presentation skills, and publication strategies. The CMBG Advisory Committee provides additional oversight on trainees’ progress, with a committee member assigned to each trainee. These features make the program a vibrant, highly interactive community of faculty and students involved in key basic science questions relevant to human health. Students graduate with a required first-author publication (or submission), with the scientific background, research skills, and critical thought process necessary for an independent career in science.

项目总结/摘要 CMBG计划培养研究生获得细胞与分子生物学和遗传学博士学位。的 该计划包括来自8个基础科学部门的54名教师，是唯一的研究生培训 计划在阿尔伯特爱因斯坦学院与广泛的，跨学科的研究重点，旨在增加 了解生物过程，为疾病诊断、治疗和 预防该应用程序取代了先前存在的计划，支持14名学员（约7名任命/年）。 在过去的15年里，我们的CMBG项目毕业了84名博士生，其中包括25名代表性不足的少数民族 学生超过95%的毕业生继续从事与科学相关的职业。总体目标是为学生 进行重大的基础科学研究项目，获得严格的科学背景和实验 培训，及时开发和捍卫他们的博士论文，并发展成为独立的科学家 在生物医学领域做出长期贡献的人。培训教师是根据研究选择的 卓越的细胞生物学，分子生物学和遗传学，并致力于指导学生， 提供良好和安全的培训环境。除了ESI的教职员工外， 经验和资金;机制到位，以协助初级教师指导学生，并提供 对学生实验室的额外监督。学员通过一个单一的研究生院门户网站进入爱因斯坦。 他们接受正式培训，负责进行研究和教学。学生完成3项研究 在第一年的轮换，并进行严格的课程，包括CMBG基础课程组织 并由我们的副主任和培训师授课。学生根据以下内容编写助学金提案类型的资格考试： 他们的博士研究，并口头捍卫它到一个跨学科的教师委员会。学生由 第一年和第二年后，CMBG咨询委员会，并在 一个为期两年的资助计划。CMBG计划活动建立了一个连贯的培训工作，其中 学生参加，直到完成博士学位。学员每年在一个积极的工作进展中展示他们的工作 系列，并主办年度学生邀请的特殊研讨会发言人。年度计划务虚会包括会谈 由高年级学生，海报，研讨会，道德和严谨性的讨论，以及来自CMBG校友的演讲 提供职业前景。在所有活动中，我们的CMBG培训师，咨询委员会，董事和助理。 主任提供研究方向，实验策略的严谨性，演讲技巧， 出版战略。CMBG咨询委员会对学员的进度提供额外的监督， 每个学员都有一名委员会成员。这些特点使该计划充满活力，高度互动 参与与人类健康相关的关键基础科学问题的教师和学生社区。学生 毕业生与所需的第一作者出版物（或提交），与科学背景，研究技能， 和批判性思维过程所必需的一个独立的职业生涯在科学。