Cell & Tissue Imaging and Data Science Core

细胞

• 批准号: 10714515
• 负责人: Sarah F Hamm-Alvarez
• 金额: $ 19.92万
• 依托单位: UNIVERSITY OF SOUTHERN CALIFORNIA
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-09-30 至 2028-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10714515
• 关键词: Algorithmic Software; Artificial Intelligence; Biological; Center Core Grants; Confocal Microscopy; Consultations; Coupled; Data; Data Science Core; Development; Electron Microscopy; Equipment; Evaluation; Experimental Designs; Goals; Histology; Image; Image Analysis; Individual; Machine Learning; Methodology; Microscopic; Microscopy; Productivity; Research; Research Personnel; Research Project Grants; Resources; Services; Specimen; Technical Expertise; Techniques; Technology; Tissue imaging; Tissues; Vision research; advanced analytics; analytical tool; artificial intelligence algorithm; cell preparation; cellular imaging; cost; imaging modality; imaging science; imaging system; implementation tool; innovation; investigator training; light microscopy; live cell imaging; operation; tissue preparation; vision science

PROJECT SUMMARY: CELL & TISSUE IMAGING AND DATA SCIENCE CORE The Cell & Tissue Imaging and Data Science Core will enhance the activities and accomplishments of ongoing research projects by providing histology services, access to a range of advanced imaging equipment, and technical expertise for image analysis and implementation of artificial intelligence (AI) approaches. It will provide essential resources for microscopic evaluation of ocular tissues and extraction of biological data from images, thereby increasing the innovative capabilities of participating investigators for conducting productive vision research. The Core will provide equipment and technical expertise for performing histology, light/confocal and electron microscopy, live cell imaging, image analysis, and development/application of AI algorithms. The specific aims are to provide resources for: 1) performing histology of ocular tissue specimens; 2) enabling investigators to evaluate ocular tissues with the use of sophisticated light/confocal and electron microscopy and emerging imaging modalities; 3) training investigators and their research staff on the utility and operation of imaging equipment; 4) consultations on cell and tissue preparation and imaging for experimental design and appropriateness of techniques; 5) providing expertise and technical support for image analysis and development of AI methodologies.

项目总结：细胞和组织成像和数据科学核心 细胞与组织成像和数据科学核心将加强正在进行的活动和成就 通过提供组织学服务，获得一系列先进的成像设备， 图像分析和人工智能（AI）方法实施的技术专长。它将 为眼组织的显微镜评价和从眼组织中提取生物学数据提供必要的资源。 图像，从而提高参与调查人员的创新能力， 视觉研究该中心将提供进行组织学检查的设备和技术专长， 光学/共聚焦和电子显微镜，活细胞成像，图像分析，以及AI的开发/应用 算法其具体目的是提供资源：1）进行组织学的眼组织标本; 2)使研究人员能够使用复杂的光/共聚焦和电子技术来评估眼组织， 显微镜和新兴的成像方式; 3）培训研究人员及其研究人员的效用和 影像设备操作; 4）细胞和组织制备和实验成像咨询 技术的设计和适当性; 5）为图像分析提供专业知识和技术支持， AI方法论的发展。