Cell & Tissue Imaging and Data Science Core

项目摘要：细胞与组织成像与数据科学核心 细胞与组织成像和数据科学核心将加强正在进行的活动和成就 通过提供组织学服务，获得一系列先进的成像设备，以及 图像分析和人工智能(AI)方法实施方面的技术专长。会的 为眼组织的显微评估和提取生物学数据提供必要的资源 图像，从而提高参与调查人员的创新能力，进行富有成效的 视觉研究。该中心将提供进行组织学检查的设备和技术专长， 光学/共聚焦显微镜和电子显微镜、活细胞成像、图像分析和人工智能的发展/应用 算法。具体目的是为以下方面提供资源：1)进行眼组织标本的组织学研究； 2)使研究人员能够使用复杂的光/共聚焦和电子技术来评估眼睛组织 显微镜和新出现的成像方式；3)培训调查人员及其研究人员关于实用和 影像设备操作；4)实验用细胞和组织制备及成像咨询 技术的设计和适当性；5)为图像分析和 发展人工智能方法论。

PROJECT SUMMARY: CELL & TISSUE IMAGING AND DATA SCIENCE CORE The Cell & Tissue Imaging and Data Science Core will enhance the activities and accomplishments of ongoing research projects by providing histology services, access to a range of advanced imaging equipment, and technical expertise for image analysis and implementation of artificial intelligence (AI) approaches. It will provide essential resources for microscopic evaluation of ocular tissues and extraction of biological data from images, thereby increasing the innovative capabilities of participating investigators for conducting productive vision research. The Core will provide equipment and technical expertise for performing histology, light/confocal and electron microscopy, live cell imaging, image analysis, and development/application of AI algorithms. The specific aims are to provide resources for: 1) performing histology of ocular tissue specimens; 2) enabling investigators to evaluate ocular tissues with the use of sophisticated light/confocal and electron microscopy and emerging imaging modalities; 3) training investigators and their research staff on the utility and operation of imaging equipment; 4) consultations on cell and tissue preparation and imaging for experimental design and appropriateness of techniques; 5) providing expertise and technical support for image analysis and development of AI methodologies.